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This book explores various approaches to designing and developing biocompatible coatings and the range of applications they offer.
Surface chemistry has a major influence on the biocompatibility of materials, and applying a suitable coating can provide a cost-effective way to ensure the compatibility of medical devices and biomaterials without compromising their physical properties. Biocompatible coatings mimic naturally occurring coatings but may offer additional functionalities, such as lubrication, resistance to abrasion, or bacterial inhibition. This book explores various approaches to designing and developing biocompatible coatings and the range of applications they offer. The editors have brought together a wealth of expertise, providing, for the first time, a comprehensive volume addressing the current needs in medicine. Consideration is given to the next generation of coating systems and industry case studies are also presented.
The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications.The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices.With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings. - Provides an extensive review of coating types and surface modifications for biomedical applications - Chapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatings - Presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices
Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. - Presents diverse insights from experts in government, industry and academia - Delivers a comprehensive overview of testing and interpreting medical device performance - Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market
The fields of Mechanical Engineering, Composite Materials, and Smart Manufacturing find themselves at the heart of a pivotal predicament. As these industries grapple with the demands for efficiency, sustainability, and innovation, a need arises for a unified exploration of the transformative solutions within these domains. At this crucial moment, researchers, academics, and practitioners worldwide need to focus on understanding and solving the complex issues that are hindering progress. Trends and Applications in Mechanical Engineering, Composite Materials and Smart Manufacturing delves into solutions that propel industries, economies, and societies into a future defined by progress and resilience. At its core, this book strives to examine the disciplines of mechanical engineering, composite materials, and smart manufacturing. With the collaborative efforts of diverse experts, it attempts to create a comprehensive resource that not only identifies emerging trends but also unveils their impact on the real world. By acting as a driving force for advancing current research, bridging knowledge gaps, and presenting innovative solutions, the publication contributes significantly to the collective understanding of these disciplines. The goal is to empower scholars, educators, and professionals with the knowledge and insights required to sculpt the future of these increasingly complex industries.
Despite advances in alternative materials, metals are still the biomaterial of choice for a number of clinical applications such as dental, orthopedic and cardiac implants. However, there are a number of intrinsic problems associated with implanting metal in the biological environment, such as wear, corrosion, biocompatibility and toxicity, which must be addressed. Modern technology has enabled scientists to modify metal surfaces or apply special coatings to metals to improve their performance safety. Surface Coating and Modification of Metallic Biomaterials will discuss the most important modification techniques and coatings for metals, first covering the fundamentals of metals as a biomaterial and then exploring surface modification techniques and coatings. - An expansive overview of surface modification techniques for biomedical use - In-depth exploration of issues arising from metal biomaterial use - Includes examples of applications in a clinical setting
Superhydrophobic Polymer Coatings: Fundamentals, Design, Fabrication, and Applications offers a comprehensive overview of the preparation and applications of polymer coatings with superhydrophobicity, guiding the reader through advanced techniques and scientific principles. Sections present detailed information on the fundamental theories and methods behind the preparation of superhydrophobic polymer coatings and demonstrate the current and potential applications of these materials, covering a range of novel and marketable uses across industry, including coatings with properties such as foul resistance and self-cleaning, anti-icing and ice-release, corrosion inhibition, antibacterial, anti-reflection, slip and drag reduction, oil-water separation, and advanced medical applications. This book is a highly valuable resource for academic researchers, scientists and advanced students working on polymer coatings or polymer surface modifications, as well as professionals across polymer science, polymer chemistry, plastics engineering, and materials science. The detailed information in this book will also be of great interest to scientists, R&D professionals, product designers and engineers who are looking to develop products with superhydrophobic coatings. - Presents in-depth information on the advanced methods required in the preparation of superhydrophobic polymer coatings - Covers the latest advances in the design of polymer coatings with superhydrophobic properties, including nanofabrication - Explains cutting-edge industrial and medical applications, including self-cleaning coatings, corrosion inhibition, anti-icing and ice-release, and oil-water separation
Medical Coatings and Deposition Technologies is an important new addition to the libraries of medical device designers and manufacturers. Coatings enable the properties of the surface of a device to be controlled independently from the underlying bulk properties; they are often critical to the performance of the device and their use is rapidly growing. This book provides an introduction to many of the most important types of coatings used on modern medical devices as well as descriptions of the techniques by which they are applied and methods for testing their efficacy. Developers of new medical devices and those responsible for producing them will find it an important reference when deciding if a particular functionality can be provided by a coating and what limitations may apply in a given application. Written as a practical guide and containing many specific coating examples and a large number of references for further reading, the book will also be useful to students in materials science & engineering with an interest in medical devices. Chapters on antimicrobial coatings as well as coatings for biocompatibility, drug delivery, radiopacity and hardness are supported by chapters describing key liquid coating processes, plasma-based processes and chemical vapor deposition. Many types of coatings can be applied by more than one technique and the reader will learn the tradeoffs given the relevant design, manufacturing and economic constraints. The chapter on regulatory considerations provides important perspectives regarding the marketing of these coatings and medical devices.
This book highlights some of the most important structural, chemical, mechanical and tribological characteristics of DLC films. It is particularly dedicated to the fundamental tribological issues that impact the performance and durability of these coatings. The book provides reliable and up-to-date information on available industrial DLC coatings and includes clear definitions and descriptions of various DLC films and their properties.
Development of new surfaces and coatings has resulted in scientific and technological progress. Coatings technology offers the possibility of producing advanced surface with tailored physicochemical and biological properties to meet requirements for food, biomedical, and environmental applications. This e-book gathers recently published papers that have attracted considerable attention and consideration, providing updates on this research topic. Specifically, this book collects new information on designed surfaces, coatings, and materials based on metals, polymers, ceramics, and composites. Some research describes the techniques for the preparation and characterization of gel, functional surfaces, and coatings, and their potential application in drug delivery or films for food preservation. Other studies outline different surface preparation processes or novel techniques for modifying the surface features for load-bearing implant applications. One paper focuses on the synthesis of stimuli-responsive hydrogels for new perspectives such as active coatings for cotton–cellulose fabric. A review is devoted to probiotic microencapsulation technology. The collection delivers scientific findings to both academic and industrial readers.