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Enter a wonderful world filled with real magic, mystery … and danger. As if being small for his age and also having S. Horten as his name isnt bad enough, now 10-year-old Stuart is forced to move far away from all his friends.But on his very first day in his new home, Stuarts swept up in an extraordinary adventure: the quest to find his great-uncle Tony--a famous magician who literally disappeared off the face of the earth--and Tonys marvelous, long-lost workshop. Along the way, Stuart reluctantly accepts help from the annoying triplets next door… and encounters trouble from another magician whos also desperate to get hold of Tonys treasures. A quirky, smart, charming page-turner, Hortens Miraculous Mechanisms will enchant young readers--as well as teachers, librarians, and parents. Long-listed for the Carnegie Medal (2012) and the Guardian Childrens Fiction Prize (2011)
Neuroscientists investigate the mechanisms of spatial memory. Molecular biologists study the mechanisms of protein synthesis and the myriad mechanisms of gene regulation. Ecologists study nutrient cycling mechanisms and their devastating imbalances in estuaries such as the Chesapeake Bay. In fact, much of biology and its history involves biologists constructing, evaluating, and revising their understanding of mechanisms. With In Search of Mechanisms, Carl F. Craver and Lindley Darden offer both a descriptive and an instructional account of how biologists discover mechanisms. Drawing on examples from across the life sciences and through the centuries, Craver and Darden compile an impressive toolbox of strategies that biologists have used and will use again to reveal the mechanisms that produce, underlie, or maintain the phenomena characteristic of living things. They discuss the questions that figure in the search for mechanisms, characterizing the experimental, observational, and conceptual considerations used to answer them, all the while providing examples from the history of biology to highlight the kinds of evidence and reasoning strategies employed to assess mechanisms. At a deeper level, Craver and Darden pose a systematic view of what biology is, of how biology makes progress, of how biological discoveries are and might be made, and of why knowledge of biological mechanisms is important for the future of the human species.
This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.
"Compliant Mechanisms" beschreibt eine besonders exakte, flexible und zuverlässige Entwurfsmethode im Maschinenbau, vorgestellt von einem international anerkannten Experten. Einem allgemeinen Überblick folgt die Erläuterung fortgeschrittener, moderner, zum Teil hochspezialisierter Anwendungen.
''Many contributors have submitted for publication in Machinery's columns most of the mechanical movements described.''.
The mechanical philosophy first emerged as a leading player on the intellectual scene in the early modern period—seeking to explain all natural phenomena through the physics of matter and motion—and the term mechanism was coined. Over time, natural phenomena came to be understood through machine analogies and explanations and the very word mechanism, a suggestive and ambiguous expression, took on a host of different meanings. Emphasizing the important role of key ancient and early modern protagonists, from Galen to Robert Boyle, this book offers a historical investigation of the term mechanism from the late Renaissance to the end of the seventeenth century, at a time when it was used rather frequently in complex debates about the nature of the notion of the soul. In this rich and detailed study, Domenico Bertoloni Melifocuses on strategies for discussing the notion of mechanism in historically sensitive ways; the relation between mechanism, visual representation, and anatomy; the usage and meaning of the term in early modern times; and Marcello Malpighi and the problems of fecundation and generation, among the most challenging topics to investigate from a mechanistic standpoint.
The advancement of social theory requires an analytical approach that systematically seeks to explicate the social mechanisms that generate and explain observed associations between events. These essays, written by prominent social scientists, advance criticisms of current trends in social theory and suggest alternative approaches. The mechanism approach calls attention to an intermediary level of analysis in between pure description and story-telling, on the one hand, and grand theorizing and universal social laws, on the other. For social theory to be of use for the working social scientist, it must attain a high level of precision and provide a toolbox from which middle range theories can be constructed.
Mechanics of Mechanisms and Machines provides a practical approach to machine statics, kinematics, and dynamics for undergraduate and graduate students and mechanical engineers. The text uses a novel method for computation of mechanism and robot joint positions, velocities, accelerations; and dynamics and statics using matrices, graphs, and generation of independent equations from a matroid form. The computational methods presented can be used for industrial and commercial robotics applications where accurate and quick mechanism/robot control is key. The book includes many examples of linkages, cams, and geared mechanisms, both planar and spatial types, having open or multiple cycles. Features • Presents real-world examples to help in the design process of planar and spatial mechanisms • Serves as a practical guide for the design of new products using mechanical motion analysis • Analyzes many applications for gear trains and auto transmissions, robotics and manipulation, and the emerging field of biomechanics • Presents novel matrix computational methods, ideal for the development of efficient computer implementations of algorithms for control or simulation of mechanical linkages, cams, and geared mechanisms • Includes mechanism animations and result data tables as well as comparisons between matrix-based equation results implemented using Engineering Equation Solver (EES) and results for the same mechanisms simulated using SolidWorks.
A new "textual studies" and archival approach to the investigation of works of new media and electronic literature that applies techniques of computer forensics to conduct media-specific readings of William Gibson's electronic poem "Agrippa," Michael Joyce's Afternoon, and the interactive game Mystery House.
Machines have always gone hand-in-hand with the cultural development of m- kind throughout time. A book on the history of machines is nothing more than a specific way of bringing light to human events as a whole in order to highlight some significant milestones in the progress of knowledge by a complementary persp- tive into a general historical overview. This book is the result of common efforts and interests by several scholars, teachers, and students on subjects that are connected with the theory of machines and mechanisms. In fact, in this book there is a certain teaching aim in addition to a general historical view that is more addressed to the achievements by “homo faber” than to those by “homo sapiens”, since the proposed history survey has been developed with an engineering approach. The brevity of the text added to the fact that the authors are probably not com- tent to tackle historical studies with the necessary rigor, means the content of the book is inevitably incomplete, but it nevertheless attempts to fulfil three basic aims: First, it is hoped that this book may provide a stimulus to promote interest in the study of technical history within a mechanical engineering context. Few are the co- tries where anything significant is done in this area, which means there is a general lack of knowledge of this common cultural heritage.