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This book presents detailed descriptions of how to set up and use several classical cardiac preparations from scratch, including whole heart, atrial, ventricular, and papillary muscles and in vivo small animal preparations. It describes methods for monitoring contraction and contractility.
Measurement of Cardiac Function presents detailed descriptions of how to set up and use several classical cardiac preparations from scratch. The preparations include whole heart, atrial, ventricular, and papillary muscles and in vivo small animal preparations. Methods for monitoring contraction and contractility are fully described. Flow charts and step-by-step instructions make it easy to understand, even for the first time investigator. This book examines the most widely used tools in experimental cardiology and provides you with the recipe-setting up the technique, procurement of equipment, sample data and calculations, problems and trouble shooting, adapting to other species, modifications, and applicability. Undoubtedly, this text will be a great asset to cardiovascular physiologists, pharmacologists, experimental cardiologists, and students of physiology and pharmacology.
First Published in 1997, Measurement of Cardiovascular Function answers the crucial need for a straightforward guide for cardiac researchers to develop techniques from scratch in the laboratory. The techniques detailed represent major models and methods used in assessing cardiac function in physiological and pathological conditions. The book presents in-depth descriptions of several sophisticated cardiac preparations and includes chapters on the lipid-perfused heart, metabolic measurements, models of arrhythmia, blood pressure monitoring, and models of hypertension. This book examines the most widely used tools in experimental cardiology and provides you with the recipe-setting up the technique, procurement of equipment, sample data and calculations, problems and trouble shooting, adapting to other species, modifications, and applicability. Undoubtedly, this text will be a great asset to cardiovascular physiologists, pharmacologists, experimental cardiologists, and students of physiology and pharmacology.
Measurement of Cardiovascular Function answers the crucial need for a straightforward guide for cardiac researchers to develop techniques from scratch in the laboratory. The techniques detailed represent major models and methods used in assessing cardiac function in physiological and pathological conditions. The book presents in-depth descriptions of several sophisticated cardiac preparations and includes chapters on the lipid-perfused heart, metabolic measurements, models of arrhythmia, blood pressure monitoring, and models of hypertension. This book examines the most widely used tools in experimental cardiology and provides you with the recipe-setting up the technique, procurement of equipment, sample data and calculations, problems and trouble shooting, adapting to other species, modifications, and applicability. Undoubtedly, this text will be a great asset to cardiovascular physiologists, pharmacologists, experimental cardiologists, and students of physiology and pharmacology.
Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice.
This authoritative, practical book presents diagnostic and therapeutic measurements useful in all areas of cardiology. It provides specific instruction on the range of numeric values that can be expected from individual tests and the significance of any variations from the norm. The book covers measurement procedures and interpretation of test results for circulatory and cardiac function, exercise hemodynamics and the electrocardiogram, ambulatory monitoring, electrophysiology, and autonomic function. It also has chapters on clinical chemistry, cardiac catheterization, echocardiography, nuclear cardiology, cardiovascular changes in pregnancy, acute myocardial infarction, cardiac surgery, and myoplasty. With its expert, comprehensive coverage of measurements in cardiology and interpretation of results, the book has special value for today s physicians and residents as a practical, reliable aid to diagnosis and therapeutic assessment. Includes bibliographic references and index.
The ultrasound velocity tomography allows measurement of cardiac geometries for various phases in the cardiac cycle. The present tomograph makes reconstruc tions at intervals of 20 ms. Because of a lack of clear (intramural) landmarks (except the roots of the papillairy muscle), it is difficult to pinpoint spatial trajectories of particular points in the heart. Therefore, a second method was developed of injecting radiopaque markers in the heart and following their motion patterns during the cardiac cycle with help of a biplane X-ray equipment. The data obtained with both methods can be implemented in our finite element model of the heart to compute intramural stresses and strains. The results obtained sofar with the extended Darcy equation to account for the interaction of blood rheology and tissue mechanics look promising. Further testing with more sophisticated subjects than mentioned in Figure 9 is required before it will be implemented in our finite element model of the heart. We conclude that analysis of regional cardiac function, including regional myocardial blood flow, requires still a major research effort but the results obtained sofar justify, to our opinion, a continuation in this direction. Acknowledgement The authors acknowledge Dr. C. Borst and coworkers for doing the animal experiments and prof. Van Campen and dr. Grootenboer for their participation is some aspects of this work.
This book offers a comprehensive overview of the basic physiology of the cardiac and pulmonary systems, tools for cardiopulmonary monitoring, and related issues in the management of specific conditions. The volume is divided into three main parts. The first part examines the functional basis of normal and abnormal physiology, organized into cardiac and pulmonary units and followed by a “combined” interactive component. The next section discusses cardiopulmonary monitoring tools and variables and is also divided into cardiac (e.g, echocardiography, heart rate, cardiac output), pulmonary (e.g, lung volume, pleural pressure, electrical impedance tomography), and combined tools such as radiology/MRI and tissue perfusion tests. The third section concerns the management and application of specific clinical problems such as pulmonary hypertension, cardiac shunts, cardiogenic shock, and ECMO with an emphasis on the physiological basics. /div Cardiopulmonary Monitoring: Basic Physiology, Tools, and Bedside Management for the Critically Ill is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, critical care, emergency medicine, anesthesiology, and radiology.
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.