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A convenient compact textbook that fits snugly into your scrubs pocket. Developed at McMaster University, the birthplace of evidence-based medicine (EBM) and one of the world's top universities, in cooperation with over 300 highly renowned scientists from North America and Poland.
Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second Edition provides readers with a comprehensive examination on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." The book covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance and a discussion of their associated acute and chronic harm and toxicity. This second edition addresses drugs new to the scene, with completely updated and revised chapters. Written by international experts in the field, this multi-authored book is an essential reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. - Includes chapters written by international experts in the field - Presents a comprehensive overview on the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance - Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies - Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene, including amphetamines and the synthetic cannabinoid receptors in 'spice' and 'K2'
Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. - First edition won Best Book in Medical Science Award from the Association of American Publishers - Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias - A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references
This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.
The new edition of this comprehensive guide to internal medicine for trainees, has been fully revised to provide the latest information and advances in the field. Each section covers the pathophysiology, signs and symptoms, investigation techniques, diagnosis and treatment options of clinical syndromes and diseases in a different organ system of the body, including the central nervous system, respiratory system, endocrine system, skin, blood, kidneys and much more. Topics have been thoroughly updated and new chapters on general physical examination and examination of the neurological, respiratory and gastrointestinal systems, have been added to the fourth edition. Clinical photographs, illustrations and tables further enhance the practical text. Key points Fully revised, new edition providing trainees with the latest advances in internal medicine Covers numerous diseases and disorders in all organ systems Fourth edition includes new chapters on physical examination Previous edition (9780729540810) published in 2015
- Chapters have been rearranged and often split to work towards one chapter-one lecture model so that the text is linked to curriculum objectives which appeals to both students and faculty. - Narrative length has been reduced while ensuring the original flow and explanation of concepts is not affected. - Updated Learning Objectives (e.g. Applied physiology of the Renal System) and Glossary of Terms in the beginning of every chapter. - Short, easy-to-read, masterfully edited chapters and a user-friendly full-color design facilitates better learning and retention. - Features expanded clinical coverage including obesity, metabolic and cardiovascular disorders, Alzheimer's disease, and other degenerative diseases. - Complex Concepts/Processes are summarized in flowcharts/flow diagram for better understanding. - Contains more than 1000 carefully crafted diagrams and drawings ensures better understanding of Physiology. - Offers Clinically Oriented perspective - bridging basic physiology with pathophysiology, including cellular and molecular mechanism important for Clinical medicine. - Updated throughout based on the Guyton and Hall Textbook of Physiology 14th edition to reflect the latest knowledge in the field. - The information of the book has been updated to include all areas of the new MCI curriculum (these are either embedded within the existing chapters or as several new chapters at the end of the book).
The Book of Echo is concise yet comprehensive, focused on the adult echocardiography. It is written to be the echo book that echocardiographer, echocardiography fellows, cardiologist, cardiology fellows, and cardiac technicians read without having to navigate through large books looking for practical or diagnostic clue. The book has 20 chapters with more than 600 illustrations covering basic technical aspect to more advanced diagnostic techniques. All provided information are in accord with the latest available echocardiography guidelines. Topics include basics physics, image acquisition and optimization techniques, echocardiography enhancing agent, stress echocardiography, echocardiographic diagnosis, introduction to congenital heart disease, and interventional echocardiography.
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
Written by Nicholas J Talley, Simon O’Connor and Brad Frankum, this engaging and instructive text provides practical pathways to diagnosis and up-to-date strategies for implementing evidence-based treatments for prevalent conditions. Learn how to: identify what is clinically important understand and investigate disease create an effective strategy for treatment use technological diagnostic tools. This new edition of Essentials of Internal Medicine 4e describes established and trusted diagnostic techniques to equip students and trainees with the skills to succeed in their profession. The visually dynamic text offers a framework of knowledge covering core facts and addressing difficult-to-master topics such as: holistic approach to patient treatment the importance of diagnosis the physician's role in public health the physician as scholar. Contributions from expert clinicians leading the advancement of medicine globally Need-to-know ‘clinical pearls’ throughout each chapter Memory jog lists and tables Multiple choice questions with end-of-chapter answers and extensive explanations Enhanced eBook version included with purchase
Prepared by residents and attending physicians at Massachusetts General Hospital, this pocket-sized looseleaf is one of the best-selling references for medical students, interns, and residents on the wards and candidates reviewing for internal medicine board exams. In bulleted lists, tables, and algorithms, Pocket Medicine provides key clinical information about common problems in internal medicine, cardiology, pulmonary medicine, gastroenterology, nephrology, hematology-oncology, infectious diseases, endocrinology, and rheumatology. This Fifth Edition is fully updated and includes a sixteen-page color insert with key and classic abnormal images. If you purchased a copy of Sabatine: Pocket Medicine 5e, ISBN 978-1-4511-8237-8, please make note of the following important correction on page 1-36: Oral anticoagulation ( Chest 2012;141: e531S; EHJ 2012;33:2719; Circ 2013;127:1916)- All valvular AF as stroke risk very high- Nonvalv. AF: stroke risk 4.5%/y; anticoag (R) 68% ̄ stroke; use a risk score to guide Rx: CHADS2: CHF (1 point), HTN (1), A ge >= 75 y (1), DM (1), prior Stroke/TIA (2)CHA2DS2-VASc: adds 65-74 y (1) >=75 y (2), vasc dis. [MI, Ao plaque, or PAD (1)]; ? (1)score 32 (R) anticoag; score 1 (R) consider anticoag or ASA (? latter reasonable if risk factor age 65-74 y, vasc dis. or ?); antithrombotic Rx even if rhythm control [SCORE CORRECTED]- Rx options: factor Xa or direct thrombin inhib (non-valv only; no monitoring required) or warfarin (INR 2-3; w/ UFH bridge if high risk of stroke); if Pt refuses anticoag, considerASA + clopi or, even less effective, ASA alone ( NEJM 2009;360:2066)Please make note of this correction in your copy of Sabatine: Pocket Medicine 5e immediately and contact LWW's Customer Service Department at 1.800.638.3030 or 1.301.223.2300 so that you may be issued a corrected page 1-36. You may also download a PDF of page 1-36 by clicking HERE. All copies of Pocket Medicine, 5e with the ISBN: 978-1-4511-9378-7 include this correction.