Download Free Mathematical Modeling And Numerical Simulation Of Controlled Drug Release Book in PDF and EPUB Free Download. You can read online Mathematical Modeling And Numerical Simulation Of Controlled Drug Release and write the review.

Numerical analysis of matter transfer is an area that pharmacists find difficult, but which is a technique frequently used in preparing controlled drug release and oral dosage forms. This book provides clear and straightforward information enabling the reader to carry out numerical analysis of matter transfer - a vital processs when looking at the formulation of oral dosage forms with controlled drug release. The drug is dispersed in a polymeric matrix either biodegradable or not, the basis of which is the transfer of the liquid and the drug through dosage form. Information on this diffusion is found either through mathematical treatment when the problem is simple, or through numerical analysis for more complex problems. Professor Vergnaud demonstrates and clarifies these, modelling the process of drug delivery by using numerical analysis and computerization. A simulation of the process is provided, together with a determination of the effects of all parameters, and the author uses both mathematical and numerical models to predict the preparation of new dosage forms able to fulfil specific conditions.
Exploring how to apply in vitro/in vivo correlations for controlled release dosage forms, Bioavailability of Drug Delivery Systems: Mathematical Modeling clearly elucidates this complex phenomena and provides a guide for the respective mathematical modeling. The book introduces mathematical modeling methods for calculating the profiles of plasma le
This book provides the most valuable and updated research on computational and mathematical models in biological systems from influential researchers around the world and contributes to the development of future research guidelines in this topic. Topics include (but are not limited to): modeling infectious and dynamic diseases; regulation of cell function; biological pattern formation; biological networks; tumor growth and angiogenesis; complex biological systems; Monte Carlo methods; Control theory, optimization and their applications
Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS
Demand for better reliability from drug delivery systems has caused designers and researchers to move away from trial-and-error approaches and toward model-based methods of product development. Developing such models requires cross-disciplinary physical, mathematical, and physiological knowledge. Combining these areas under a single cover, Under
The main objective of the development of drug delivery devices is to successfully deliver the drug to the desired sites of therapeutic action while reducing adverse side effects. In this paper, mathematical models have been developed for controlled drug delivery from cylindrical shaped devices consisting of disks, which is covered by erodible polymer and membrane. The use of polymers is necessary to provide controlled long term delivery of drugs. These implants need not be removed after drug delivery from the body because these are erodible. A model is presented for delivered of the drug from the device to the body. This model provides design of drug delivery device for eroding tumour or chemotherapy to cancerous regions and many such diseases. The results have been obtained for steady state release time and life time of the device. It has been observed that life time increases by adjusting some parameters.
This book provides an up-to-date overview of research articles in applied and industrial mathematics in Italy. This is done through the presentation of a number of investigations focusing on subjects as nonlinear optimization, life science, semiconductor industry, cultural heritage, scientific computing and others. This volume is important as it gives a report on modern applied and industrial mathematics, and will be of specific interest to the community of applied mathematicians. This book collects selected papers presented at the 9th Conference of SIMAI. The subjects discussed include image analysis methods, optimization problems, mathematics in the life sciences, differential models in applied mathematics, inverse problems, complex systems, innovative numerical methods and others. Sample Chapter(s). Chapter 1: Multichannel Wavelet Scheme for Color Image Processing (759 KB). Contents: Existence and Uniqueness for a Three Dimensional Model of Ferromagnetism (V Berti et al.); Wave Propagation in Continuously-Layered Electromagnetic Media (G Caviglia & A Morro); Mathematical Models for Biofilms on the Surface of Monuments (F Clarelli et al.); Conservation Laws with Unilateral Constraints in Traffic Modeling (R M Colombo et al.); On a Model for the Codiffusion of Isotopes (E Comparini et al.); Multiscale Models of Drug Delivery by Thin Implantable Devices (C D''Angelo & P Zunino); A Mathematical Model of Duchenne Muscular Dystrophy (G Dell''Acqua & F Castiglione); A Dissipative System Arising in Strain-Gradient Plasticity (L Giacomelli & G Tomassetti); Material Symmetry and Invariants for a 2D Fiber-Reinforced Network with Bending Stiffness (G Indelicato); Kinetic Treatment of Charge Carrier and Phonon Transport in Graphene (P Lichtenberger et al.); Mathematical Models and Numerical Simulation of Controlled Drug Release (S Minisini & L Formaggia); A Lattice Boltzmann Model on Unstructured Grids with Application in Hemodynamics (G Pontrelli et al.); Toward Analytical Contour Dynamics (G Riccardi & D Durante); Thermo-Mechanical Modeling of Ground Deformation in Volcanic Areas (D Scandura et al.); and other papers. Readership: Researchers in applied and computational mathematics.