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For 1,600 years Dioscorides (ca. AD 40–80) was regarded as the foremost authority on drugs. He knew mild laxatives and strong purgatives, analgesics for headaches, antiseptics for wounds, emetics to rid one of ingested poisons, chemotherapy agents for cancer treatments, and even oral contraceptives. Why, then, have his works remained obscure in recent centuries? Because of one small oversight (Dioscorides himself thought it was self-evident): he failed to describe his method for organizing drugs by their affinities. This omission led medical authorities to use his materials as a guide to pharmacy while overlooking Dioscorides' most valuable contribution—his empirically derived method for observing and classifying drugs by clinical testing. Dioscorides' De materia medica, a five-volume work, was written in the first century. Here revealed for the first time is the thesis that Dioscorides wrote more than a lengthy guide book. He wrote a great work of science. He had said that he discovered the natural order and would demonstrate it by his arrangement of drugs from plants, minerals, and animals. Until John M. Riddle's pathfinding study, no one saw the genius of his system. Botanists from the eighteenth century often attempted to find his unexplained method by identifying the sequences of his plants according to the Linnean system but, while there are certain patterns, there remained inexplicable incoherencies. However, Dioscorides' natural order as set down in De materia medica was determined by drug affinities as detected by his acute, clinical ability to observe drug reactions in and on the body. So remarkable was his ability to see relationships that, in some cases, he saw what we know to be common chemicals shared by plants of the same and related species and other natural product drugs from animal and mineral sources. Western European and Islamic medicine considered Dioscorides the foremost authority on drugs, just as Hippocrates is regarded as the Father of Medicine. They saw him point the way but only described the end of his finger, despite the fact that in the sixteenth century alone there were over one hundred books published on him. If he had explained what he thought to be self-evident, then science, especially chemistry and medicine, would almost certainly have developed differently. In this culmination of over twenty years of research, Riddle employs modern science and anthropological studies innovatively and cautiously to demonstrate the substance to Dioscorides' authority in medicine.
"Traditional Chinese medicine has been practiced in various forms for more than a thousand years. Practitioners may heal patients with herbal remedies, acupuncture, massage, exercise, and modified diets. Even today, herbal medicines are of particular importance; Chinese pharmacies containing a vast array of remedies can be found in cities and towns the world over. This book is an interdisciplinary and cultural history of the concept of "pharmacy," both the drugs themselves and the trade in medicine, during the Ming and Qing dynasties of early modern China. This was a time of change for traditional Chinese medicine and for Chinese science as a whole. Many historians have argued that sixteenth-century China was a high point of scientific inquiry, followed by a period of intellectual decline. Though political and intellectual shifts led to a crisis of authority over pharmaceutical knowledge in the sixteenth through eighteenth centuries, Bian argues that this period of supposed intellectual decline was in fact characterized by numerous efforts to further refine and spread the pharmacological knowledge amassed in the Ming dynasty. She draws on a wide range of primary sources, but particularly through the study of bencao (pronounced "pen ts'ao"), a genre of encyclopaedic works, often called matteria medica or pharmacopoeia in the West, that collect information on medicinal substances. As the early modern Chinese Empire expanded and print culture became more widespread, the pursuit of medical remedies became a significant commercial enterprise. The author connects theory and practice of pharmacy during the Ming and Qing dynasties to broader developments in intellectual history, book culture, commerce, and taxation"--
Compound Remedies examines the equipment, books, and remedies of colonial Mexico City’s Herrera pharmacy—natural substances with known healing powers that formed part of the basis for modern-day healing traditions and home remedies in Mexico. Paula S. De Vos traces the evolution of the Galenic pharmaceutical tradition from its foundations in ancient Greece to the physician-philosophers of medieval Islamic empires and the Latin West and eventually through the Spanish Empire to Mexico, offering a global history of the transmission of these materials, knowledges, and techniques. Her detailed inventory of the Herrera pharmacy reveals the many layers of this tradition and how it developed over centuries, providing new perspectives and insight into the development of Western science and medicine: its varied origins, its engagement with and inclusion of multiple knowledge traditions, the ways in which these traditions moved and circulated in relation to imperialism, and its long-term continuities and dramatic transformations. De Vos ultimately reveals the great significance of pharmacy, and of artisanal pursuits more generally, as a cornerstone of ancient, medieval, and early modern epistemologies and philosophies of nature.
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs' activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. - Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes - Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis - Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine - Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues - References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
This is the first detailed analysis of an immensely popular 13th c. Arabic guide for pharmacists, from a time in which Jewish physicians and pharmacists worked alongside Muslim and Christian practioners. "Minh j al-dukk n" ("How to manage a pharmacy"), by Ab l-Mun al-K h n al- A r (fl. 1260) is the first attempt to explore the full spectrum of pharmacy in the medieval Arabic world: identification of the materia medica and methods of preparation; pharmacy's place within the sciences and particularly its relationship with medicine; the social position of the pharmacist and his role in the marketplace and the hospital; the economics of pharmacy; legal aspects of pharmacy; and the image of the pharmacist in literature and drama. The result is a full and nuanced picture of a section of society usually invisible.
This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. There are stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners.