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This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
Provides readers with a systematic review of the origins, history, and statistical foundations of Propensity Score Analysis (PSA) and illustrates how it can be used for solving evaluation and causal-inference problems.
Matched sampling is often used to help assess the causal effect of some exposure or intervention, typically when randomized experiments are not available or cannot be conducted. This book presents a selection of Donald B. Rubin's research articles on matched sampling, from the early 1970s, when the author was one of the major researchers involved in establishing the field, to recent contributions to this now extremely active area. The articles include fundamental theoretical studies that have become classics, important extensions, and real applications that range from breast cancer treatments to tobacco litigation to studies of criminal tendencies. They are organized into seven parts, each with an introduction by the author that provides historical and personal context and discusses the relevance of the work today. A concluding essay offers advice to investigators designing observational studies. The book provides an accessible introduction to the study of matched sampling and will be an indispensable reference for students and researchers.
Motivation is key to substance use behavior change. Counselors can support clients' movement toward positive changes in their substance use by identifying and enhancing motivation that already exists. Motivational approaches are based on the principles of person-centered counseling. Counselors' use of empathy, not authority and power, is key to enhancing clients' motivation to change. Clients are experts in their own recovery from SUDs. Counselors should engage them in collaborative partnerships. Ambivalence about change is normal. Resistance to change is an expression of ambivalence about change, not a client trait or characteristic. Confrontational approaches increase client resistance and discord in the counseling relationship. Motivational approaches explore ambivalence in a nonjudgmental and compassionate way.
An observational study is an empiric investigation of effects caused by treatments when randomized experimentation is unethical or infeasible. Observational studies are common in most fields that study the effects of treatments on people, including medicine, economics, epidemiology, education, psychology, political science and sociology. The quality and strength of evidence provided by an observational study is determined largely by its design. Design of Observational Studies is both an introduction to statistical inference in observational studies and a detailed discussion of the principles that guide the design of observational studies. Design of Observational Studies is divided into four parts. Chapters 2, 3, and 5 of Part I cover concisely, in about one hundred pages, many of the ideas discussed in Rosenbaum’s Observational Studies (also published by Springer) but in a less technical fashion. Part II discusses the practical aspects of using propensity scores and other tools to create a matched comparison that balances many covariates. Part II includes a chapter on matching in R. In Part III, the concept of design sensitivity is used to appraise the relative ability of competing designs to distinguish treatment effects from biases due to unmeasured covariates. Part IV discusses planning the analysis of an observational study, with particular reference to Sir Ronald Fisher’s striking advice for observational studies, "make your theories elaborate." The second edition of his book, Observational Studies, was published by Springer in 2002.
A review and analysis of 1000 studies on alcoholism and psychosocial treatment. The author evaluates the major conceptual approaches to alcoholism, analyzes the methodological strategies of comparative outcome research and suggests administrative solutions to matching clients and treatments.
The contributors to Best Practices in Quantitative Methods envision quantitative methods in the 21st century, identify the best practices, and, where possible, demonstrate the superiority of their recommendations empirically. Editor Jason W. Osborne designed this book with the goal of providing readers with the most effective, evidence-based, modern quantitative methods and quantitative data analysis across the social and behavioral sciences. The text is divided into five main sections covering select best practices in Measurement, Research Design, Basics of Data Analysis, Quantitative Methods, and Advanced Quantitative Methods. Each chapter contains a current and expansive review of the literature, a case for best practices in terms of method, outcomes, inferences, etc., and broad-ranging examples along with any empirical evidence to show why certain techniques are better. Key Features: Describes important implicit knowledge to readers: The chapters in this volume explain the important details of seemingly mundane aspects of quantitative research, making them accessible to readers and demonstrating why it is important to pay attention to these details. Compares and contrasts analytic techniques: The book examines instances where there are multiple options for doing things, and make recommendations as to what is the "best" choice—or choices, as what is best often depends on the circumstances. Offers new procedures to update and explicate traditional techniques: The featured scholars present and explain new options for data analysis, discussing the advantages and disadvantages of the new procedures in depth, describing how to perform them, and demonstrating their use. Intended Audience: Representing the vanguard of research methods for the 21st century, this book is an invaluable resource for graduate students and researchers who want a comprehensive, authoritative resource for practical and sound advice from leading experts in quantitative methods.