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Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. - Contributions from leading international authorities in the field - Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system - Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator
A fascinating account of football culture in Egypt through its ultras groups The history of Cairo’s football fans is one of the most poignant narratives of the 25 January 2011 Egyptian uprising. The Ultras Al-Ahly and the Ultras White Knights fans, belonging to the two main teams, Al-Ahly F.C. and Zamalek F.C respectively, became embroiled in the street protests that brought down the Mubarak regime. In the violent turmoil since, the Ultras have been locked in a bitter conflict with the Egyptian security state. Tracing these social movements to explore their role in the uprising and the political dimension of soccer in Egypt, Ronnie Close provides a vivid, intimate sense of the Ultras’ unique subculture. Cairo’s Ultras: Resistance and Revolution in Egypt’s Football Culture explores how football communities offer ways of belonging and instill meaning in everyday life. Close asks us to rethink the labels ‘fans’ or ‘hooligans’ and what such terms might really mean. He argues that the role of the body is essential to understanding the cultural practices of the Cairo Ultras, and that the physicality of the stadium rituals and acerbic chants were key expressions that resonated with many Egyptians. Along the way, the book skewers media clichés and retraces revolutionary politics and social networks to consider the capacity of sport to emancipate through performances on the football terraces.
For half a century, Madeleine L'Engle has touched many lives through her books. This biography, written with L'Engle's authorization, chronicles her life, philosophy, and spiritual journey, and gives an intimate look into the life of one of America's most prolific writers.
'Harry Leslie Smith is a vital and powerful voice speaking across generations about the struggle for a just society' Jeremy Corbyn THIS A CALL TO ARMS FOR THE MANY, NOT THE FEW: DON'T LET THE PAST BECOME OUR FUTURE Harry Leslie Smith is a great British stalwart. A survivor of the Great Depression, a Second World War veteran, a lifelong Labour supporter and a proud Yorkshire man, Harry's life has straddled two centuries. As a young man, he witnessed a country in crisis with no healthcare, no relief for the poor, and a huge economic gulf between the North and South. Now in his nineties, Harry wanders through the streets of his youth and wonders whether anything has actually changed. Britain is at its most dangerous juncture since Harry's youth - the NHS and social housing are in crisis, whilst Brexit and an unpopular government continue to divide the country - but there is hope. Just as Clement Attlee provided hope in 1945, Labour's triumphant comeback of June 2017 is a beacon of light in this season of discontent. Britain has overcome adversity before and will do so again - a new nation will be forged from the ashes of grave injustice. Moving and passionate, Don't Let My Past be Your Future interweaves memoir and polemic in a call to arms. Above all, this book is a homage to the boundless grace and resilience of the human spirit.
Much of the progress in the diagnosis, classification, and treatment of childhood hematological disorders has come from a partnership between clinicians and scientists. Indeed, access to molecular techniques is now an integral part of the practice of modern pediatric hematology. The aim of Pediatric Hematology: Methods and Protocols is to provide a collection of scientific protocols that cover the major aspects of the discipline. Most clinicians will be familiar with the difficulties inherent in establishing the underlying diagnosis in genetic marrow failure syndromes. A particular concern is failure to diagnose those associated with DNA repair defects. In Chapter 1, Dokal and colleagues present simple protocols for the molecular investigation of Fanconi anemia and dyskeratosis congenita. Molecular diagnosis is also important in children with congenital pure red cell aplasia, owing to the highly variable phenotype of this condition. In Chapter 2, Ball describes relevant protocols for the investigation of Diamond–Blackfan anemia. Hereditary hemoglobinopathy is a major cause of death and morbidity throughout the world. This area has seen great advances in screening and antenatal diagnosis. In Chapter 3, Old details protocols for the molecular diagnosis of most forms of hemoglobinopathy. High-quality, accurate molecular testing on small amounts of material has been fundamental to progress in antenatal diagnostics. The introduction to his comprehensive chapter includes a discussion of the general principles that underpin these studies. In contrast to hemoglobinopathy, severe hemophilia is uncommon.