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Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
Established by Congress in 1901, the National Bureau of Standards (NBS), now the National Institute of Standards and Technology (NIST), has a long and distinguished history as the custodian and disseminator of the United States' standards of physical measurement. Having reached its centennial anniversary, the NBS/NIST reflects on and celebrates its first century with this book describing some of its seminal contributions to science and technology. Within these pages are 102 vignettes that describe some of the Institute's classic publications. Each vignette relates the context in which the publication appeared, its impact on science, technology, and the general public, and brief details about the lives and work of the authors. The groundbreaking works depicted include: A breakthrough paper on laser-cooling of atoms below the Doppler limit, which led to the award of the 1997 Nobel Prize for Physics to William D. Phillips The official report on the development of the radio proximity fuse, one of the most important new weapons of World War II The 1932 paper reporting the discovery of deuterium in experiments that led to Harold Urey's1934 Nobel Prize for Chemistry A review of the development of the SEAC, the first digital computer to employ stored programs and the first to process images in digital form The first paper demonstrating that parity is not conserved in nuclear physics, a result that shattered a fundamental concept of theoretical physics and led to a Nobel Prize for T. D. Lee and C. Y. Yang "Observation of Bose-Einstein Condensation in a Dilute Atomic Vapor," a 1995 paper that has already opened vast new areas of research A landmark contribution to the field of protein crystallography by Wlodawer and coworkers on the use of joint x-ray and neutron diffraction to determine the structure of proteins
Born in Italy to a well-to-do Jewish family, Emilio Segrè (1905-1989) became Enrico Fermi’s first graduate student in 1928, contributed to the discovery of slow neutrons and was appointed director of the University of Palermo’s physics laboratory in 1936. While visiting the Radiation Laboratory in Berkeley, California in 1938, he learned that he had been dismissed from his Palermo post by Mussolini’s Fascist regime. Ernest O. Lawrence hired him to work on the cyclotron at Berkeley with Luis Alvarez, Edwin McMillan, and Glenn Seaborg. Segrè was one of the first to join Oppenheimer at Los Alamos, where he became a group leader on the Manhattan Project. In 1959, he won the Nobel Prize in physics for the discovery of the antiproton. He was a professor of physics at UC Berkeley from 1946 until 1972. “[A] readable, absorbing, interesting autobiography... A valuable contribution by a person who witnessed the development of much of modern nuclear physics. Segrè’s description of the historic neutron experiments performed in Rome during the mid-1930s by Enrico Fermi’s group, of which Segrè was a member, is of inestimable worth.” — Glenn T. Seaborg, Physics Today “A Mind Always in Motion is Emilio Segrè’s account — published four years after his death in 1989 — of his personal life and his life in physics... It is absorbing, moving in places and frequently revealing. Segrè noted in his preface, ‘I have not sought to display manners and tact I never had, and I have tried to treat myself no better than any one else.’ He ably succeeded in these purposes.” — Daniel J. Kevles, Nature “For general readers with an interest in the history of nuclear physics, Segrè... is among the most personable witnesses.” — Publishers Weekly
This text presents the history of the development of fibre optic technology, explaining the scientific challenges that needed to be overcome, the range of applications and future potential for this fundamental communications technology.
In November 1891, wealthy former abolitionist and Chicago politician Amos Throop founded a thoroughly undistinguished small college in Pasadena, California, which he named after himself. Millikan’s School is the history of this institution that stands today at the pinnacle of world academics, with 300 full-time faculty, nearly 1,000 undergraduate, 1,250 graduate students and 39 Caltech and alumni Nobel Prize recipients. Although Amos Throop — the name of the college was changed to Caltech in 1920 — could not have realized the importance of geography, the fact that Pasadena lay at the foot of Mount Wilson, was central to its success: astronomer George Ellery Hale built his telescope there in 1902, the finest at that time in the world. Later Hale joined the board of trustees of the struggling school and persuaded Arthur Amos Noyes, former president of MIT and the nation’s leading physical chemist, to join him in Pasadena. The third member of Caltech’s founding troika was renowned physicist Robert A. Millikan from the University of Chicago. The dedication of Caltech in 1920 and the proclamation of what it stood for in science and education set the stage for Millikan, who functioned as the school’s president, to bring the best and the brightest from all over the world — Theodore von Kármán in aeronautics, Thomas Hunt Morgan in biology, Paul Sophus Epstein in physics, Beno Gutenberg in seismology, Linus Pauling in chemistry — to Pasadena to work in an ever larger number of areas in science and technology. The book also covers the funding, planning and construction of the 200-inch telescope on Palomar Mountain, Willy Fowler’s work in nuclear astrophysics and the wartime rocket experiments that grew into the Jet Propulsion Laboratory (JPL), today the world leader in deep-space exploration. “Millikan’s School presents an interesting and thoroughly reliable account of the astonishing change over a period of a few years of a small technical school in Pasadena, California, into one of the world’s leading scientific institutions. “ — Linus Pauling “In Millikan’s School, Judith Goodstein tells the remarkable story of the rise of Caltech... She details how Millikan, aided by Hale and Arthur Amos Noyes, America’s leading physical chemist and another of Hale’s inspired acquisitions, took a former trade school and forged from it a ‘grandiose university among the orange groves’... It would be impossible, while reading Goodstein’s lively account, not to be impressed by the energy, drive and boundless enthusiasm of men like Millikan, Hale and Noyes... [who] had the bare-faced audacity to set about building an institute to rival the cream of the universities of Europe and America.” — Marcus Chown, New Scientist “[Goodstein’s] story is first and foremost the tale of three men: the astronomer George Ellery Hale, the chemist Alfred Noyes, and the physicist Robert Millikan. It is the story of their attempts to transform an undistinguished little school founded in 1891... into a world-class scientific establishment... [A] useful book.” — Tony Rothman, Science “In Millikan’s School, the story of Throop [University]’s transformation into Caltech is told with precision... Judith Goodstein’s history offers a quick tour of the landmarks of science in the mid-20th Century and a glance at how pure science puts itself at the service of government, commerce and the military... Goodstein... approaches her subject with a healthy sense of humor and an acute sense of academic politics. She tells a wonderful story about how Caltech lost to Princeton in a bidding war over the services of Albert Einstein, for example... To her credit, Goodstein asks the hard question: ‘What is the best way to do science?’... Millikan’s School offers enough hard data to enable us to come to our own conclusions.” — Jonathan Kirsch, Los Angeles Times “A cleanly written, scientifically well informed account of one of the world’s foremost institutions for science and technology.” — Ed Regis, Nature “Relying on archival material, published secondary sources, and interviews with institute scientists, Goodstein presents a highly readable account of Caltech’s beginnings at the turn of the century... substantive, informative, and a good read.” — Rebecca S. Lowen, Technology and Culture “As a history of science, this book is well crafted. Orderly in its flow, it is not only a tribute to Millikan, but also places him within the development of physics as a field.” — Andrew Rolle, Southern California Quarterly “A fascinating history that speaks to issues far larger than Cal Tech itself... This well-written and honest account (witness the many cited instances of anti-Semitism in the scientific world) is both a good read and a sobering reminder that big science and top schools are not brought by storks.” — Carroll Pursell, History of Education Quarterly “The author focuses on the personalities and the research fields of the principal scientific figures... The [...] emphasis on personalities, and capsule surveys of relevant scientific fields produce a book that can be apprehended by a wide audience.” — Roger Geiger, Isis “This chronicle offers glimpses of the passion and drive that have motivated a roster of distinguished scientists.” — Publishers Weekly “A lively tale... [Goodstein’s] individual profiles are lean and candid; her background on subjects as diverse as nuclear astrophysics, seismology, aeronautical design, quantum mechanics and rocket fuel are crisp and understandable... With a light style... and meticulous documentation, Goodstein has produced a tale worthy of her subject... “ — Marshall Robinson, Foundation News “A distinguished and uniquely American institution has found its chronicler and its chronicle in Judith Goodstein’s thorough but compact story of Millikan ‘s School. The emergence of Caltech as a powerhouse of science and engineering and a makeweight in the technological advancement of 20th century industry is both beautifully and reliably presented.” — Harry Woolf, Institute for Advanced Study, Princeton University