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Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially Neurotoxic: Palytoxin, and Methods for assessing the presence of marine neurotoxins. - Focuses on the human nervous system and the effects marine toxins have on its function - Provides the latest information on established and potential neurotoxins - Includes updates on food related toxins
This paper provides an extensive review of different aspects of five shellfish-poisoning syndromes (paralytic, diarrhoeic, amnesic, neurologic and azapiracid), as well as one fish-poisoning syndrome (ciguatera fish poisoning), and discusses in detail the causative toxins produced by marine organisms, chemical structures and analytical methods of the toxins, habitat and occurrence of the toxin-producing organisms, case studies and existing regulations. Based on this analysis, risk assessments are carried out for each of the toxins, and recommendations are elaborated to improve the management of these risks in order to reduce the harmful effect of these toxins on public health.
Food Quality: Balancing Health and Disease, Volume Thirteen in the Handbook of Food Bioengineering series, provides essential information for researchers, scientists and students on the relationship between the quality of foods and disease at the biological level. It presents different technological approaches to detect food properties and their capabilities for balancing health and disease to deliver high-quality products to consumers. This volume explores the dynamic potential of how food bioengineering can improve traditional foods through modern methods to make a positive impact on human health and foster innovation. - Provides information on how bioavailability of nutrients and food formulation can be used to prevent or improve disease - Includes the most recent research methods of metabolomics and genomics to detect best outcomes - Includes innovative applications for anti-aging effects and curative properties in foods - Presents research examples on how both human gut microbiota and food components control the way certain organisms develop and react in different environmental conditions
Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors. Nanobiosensors - From Design to Applications will prove a source of inspiration for research on biosensors, their local level development and consequently using for practical application in different industries such as food, biomedical diagnosis, pharmaceutics, agriculture, drug discovery, forensics, etc. * Discusses the latest technology and advances in the field of nanobiosensors and their applications in human diseases, drug detection, toxins * Offers a broad and comprehensive view of cutting-edge research on advanced materials such as carbon materials, nitride based nanomaterials, metal and metal oxide based nanomaterials for the fast-developing nanobiosensors research * Goes to a wide scientific and industry audience Nanobiosensors - From Design to Applications is a resource for polymer chemists, spectroscopists, materials scientists, physical chemists, surface chemists, and surface physicists.
Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. - New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology - Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe - Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology - Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology
This paper provides an extensive review of different aspects of five shellfish-poisoning syndromes (paralytic, diarrhoeic, amnesic, neurologic and azapiracid), as well as one fish-poisoning syndrome (ciguatera fish poisoning). It discusses in detail the causative toxins produced by marine organisms, chemical structures and analytical methods, habitat and occurrence of the toxin-producing organisms, case studies and existing regulations. Based on this analysis, risk assessments are carried out for each of the toxins, and recommendations are elaborated to improve the management of these risks in order to reduce the harmful effects of these toxins on public health. Contents Chapter 1: Introduction; Chapter 2: Paralytic Shellfish Poisoning (PSP); Chemical structures and properties, Methods of analysis, Source organism(s) and habitat, Occurrence and accumulation in seafood, Toxicity of PSP toxins, Prevention of PSP intoxication, Cases and outbreaks of PSP, Regulations and monitoring; Chapter 3: Diarrhoeic Shellfish Poisoning (DSP); Chemical structures and properties, Methods of analysis, Source organism(s) and habitat, Occurrence and accumulation in seafood, Toxicity of DSP toxins, Prevention of DSP intoxication, Cases and outbreaks of DSP, Regulations and monitoring; Chapter 4: Amnesic Shellfish Poisoning (ASP); Chemical structures and properties, Methods of analysis, Source organism(s) and habitat, Occurrence and accumulation in seafood, Toxicity of ASP toxins, Prevention of ASP toxins, Prevention of ASP intoxication, Cases and outbreaks of ASP, Regulations and monitoring; Chapter 5: Neurologic Shellfish Poisoning (NSP); Chemical structures and properties, Methods of analysis, Source organism(s) and habitat, Occurrence and accumulation in seafood, Toxicity of NSP toxins, Prevention of NSP intoxication, Cases and outbreaks of NSP, Regulations and monitoring; Chapter 6: Azaspiracid Shellfish Poisoning (AZP); Chemical structures and properties, Methods of analysis, Source organism(s) and habitat, Occurrence and accumulation in seafood, Toxicity of AZP toxins, Prevention of AZP intoxication, Cases and outbreaks of AZP, Regulations and monitoring; Chapter 7: Ciguatera Fish Poisoning (CFP); Chemical structures and properties of ciguatoxins, Methods of analysis, Source organism(s), habitat and distribution, Occurrence and accumulation in seafood, Toxicity of CFP toxins, Prevention of CFP intoxication, Cases and outbreaks of CFP, Regulations and monitoring; Chapter 8: Risk Assessment; Risk assessment for paralytic shellfish poisoning (PS), Risk assessment for diarrhoeic shellfish poisoning (DSP), Risk assessment for Amnesic shellfish poisoning (ASP), Risk assessment for neurologic shellfish poisoning (NSP), Risk assessment for azaspiracid shellfish poisoning (AZP), Risk assessment for ciguatera fish poisoning (CFP); Chapter 9: Conclusions and Recommendations; Conclusions, Recommendations.
Biomarkers in Toxicology is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This book includes both vertebrate and non-vertebrate species models for toxicological testing and development of biomarkers. Divided into several key sections, this reference volume contains chapters devoted to topics in molecular-cellular toxicology, as well as a look at the latest cutting-edge technologies used to detect biomarkers of exposure and effects. Each chapter also contains several references to the current literature and important resources for further reading. Given this comprehensive treatment, Biomarkers in Toxicology is an essential reference for all those interested in biomarkers across several scientific and biomedical fields. - Written by international experts who have evaluated the expansive literature to provide you with one resource covering all aspects of toxicology biomarkers - Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure and effect of chemicals of different classes - Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation and much more
Harmful Algal Blooms: A Compendium Desk Reference erläutert die Grundlagen der schädlichen Algenblüte (HAB) und bietet die notwendigen technischen Informationen, wenn es um unerwartete oder unbekannte schädliche Ereignisse in Zusammenhang mit Algen geht. Dieses Fachbuch behandelt die Gründe für die schädliche Algenblüte, erfolgreiche Management- und Monitoring-Programme, Kontroll-, Präventions- und Minderungsstrategien, die wirtschaftlichen Folgen, Gesundheitsrisiken sowie die Folgen für die Nahrungskette und Ökosysteme. Darüber hinaus bietet es ausführliche Informationen zu den häufigsten HAB-Arten. Harmful Algal Blooms: A Compendium Desk Reference ist ein unschätzbares Referenzwerk für Manager, Einsteiger in das Fachgebiet, Praktiker mit eingeschränkten Zugang zu wissenschaftlicher Literatur und alle, die schnell Zugriff auf Informationen benötigen, insbesondere vor dem Hintergrund neuartiger oder unerwarteter HAB-Ereignisse. Die drei Herausgeber gehören zu den weltweit führenden Forschern auf dem Fachgebiet. Führende Experten haben ebenfalls zu diesem Fachbuch beigetragen, das sich zu einem wichtigen Referenzwerk des Fachgebiets entwickeln wird, zumal das Thema immer mehr an Bedeutung gewinnt.
Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. - Emphasizes the integration of chromatographic methods and sample preparation - Explains how liquid chromatography is used in different industrial sectors - Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) - Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making
With the ever-increasing incidence of harmful cyanobacterial algal blooms, this monograph has added urgency and will be essential reading for all sorts of researchers, from neuroscientists to cancer research specialists. The volume contains the proceedings of the 2005 International Symposium on Cyanobacterial Harmful Algal Blooms, and has been edited by H. Kenneth Hudnell, of the US Environmental Protection Agency. It contains much of the most recent research into the subject.