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This book explores cutting-edge research on the discovery and application of marine bioactive molecules for biomedical and pharmacotherapeutic purposes. The book begins by delving into the bioprospection of marine sponge microbiomes for bioactive metabolites using advanced metagenomics tools. It then explores metagenome mining approaches for the discovery of marine microbial natural products. The use of marine-derived fungi as a source of anticancer secondary metabolites is also discussed. The book then turns to the biomedical applications of marine-derived biomaterials, including marine biopolymers in tissue engineering and regenerative medicine. Marine-derived pharmaceuticals and polymeric nanostructures for cancer treatment are also examined. Next, the book looks at the use of marine microbial sources for the synthesis of metallic nanomaterials, prospects, current development, and challenges in nanomedicine. The book continues by exploring the treasure trove of natural polymers for tissue engineering in the marine environment. It also discusses the immunomodulatory and therapeutic potential of marine-derived astaxanthin, current developments, and prospects. Finally, the book concludes by exploring the recent progress in marine-derived nutraceuticals and marine phytoplankton bioactive compounds and their applications in medicine.
In recent years, the exploration of marine ecosystems has unveiled a plethora of bioactive compounds with remarkable therapeutic potential. The oceans, covering over 70% of the Earth’s surface, are a rich source of biodiversity, harbouring organisms that have evolved unique biochemical pathways to survive in extreme conditions. These marine metabolites, produced by marine microorganisms, invertebrates, and algae, have demonstrated significant pharmacological activities, ranging from antimicrobial and anti-inflammatory to anticancer and neuroprotective properties. Marine Metabolites in Disease Management compiles and synthesizes current research on the role of marine-derived compounds in the prevention and treatment of various diseases. This work is a collaborative effort, bringing together insights from leading researchers and clinicians who have dedicated their careers to the study of marine natural products. Through their contributions, the gap between marine biotechnology and clinical applications is bridged, providing a comprehensive resource for researchers, healthcare professionals, and policymakers.
This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R and D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
The book entitled “Biodiversity of Marine Microbes” aims at highlighting the significance of marine microbes as primary producers, their contribution in complex ecological processes and their roles in biogeochemical cycles and ecosystem functioning. The book includes five research papers covering the diversity and composition of marine microbial communities representing all three domains of life in various marine environments, including coastal eutrophic areas, ice waters, and lagoons. One paper examines the diversity and succession of bacterial and archaeal communities from coastal waters in mesocosm experiments. The combination of classical tools with novel technological advances implemented in the methods of the papers offered an opportunity to answer fundamental questions and shed light on the complex and diverse life of marine microbes.
Seaweed Polysaccharides: Isolation, Biological, and Biomedical Applications examines the isolation and characterization of algal biopolymers, including a range of new biological and biomedical applications. In recent years, significant developments have been made in algae-based polymers (commonly called polysaccharides), and in biomedical applications such as drug delivery, wound dressings, and tissue engineering. Demand for algae-based polymers is increasing and represent a potential—very inexpensive—resource for these applications. The structure and chemical modification of algal polymers are covered, as well as the biological properties of these materials – including antithrombic, anti-inflammatory, anticoagulant, and antiviral aspects. Toxicity of algal biopolymers is also covered. Finally, the book introduces and explains real world applications of algal-based biopolymers in biomedical applications, including tissue engineering, drug delivery, and biosensors. This is the first book to cover the extraction techniques, biomedical applications, and the economic perspective of seaweed polysaccharides. It is an essential text for researchers and industry professionals looking to work with this renewable resource. - Provides comprehensive coverage of the research currently taking place in biomedical applications of algae biopolymers - Includes practical guidance on the isolation, extraction, and characterization of polysaccharides from sustainable marine sources - Covers the extraction techniques, biomedical applications, and economic outlook of seaweed polysaccharides
Recent Advances in Micro- and Macroalgal Processing A comprehensive review of algae as novel and sustainable sources of algal ingredients, their extraction and processing This comprehensive text offers an in-depth exploration of the research and issues surrounding the consumption, economics, composition, processing and health effects of algae. With contributions from an international team of experts, the book explores the application of conventional and emerging technologies for algal processing. The book includes recent developments such as drying and milling technologies along with advancements in sustainable greener techniques. The text also highlights individual groups of compounds including polysaccharides, proteins, polyphenols, carotenoids, lipids and fibres from algae. The authors provide insightful reviews of the traditional and more recent applications of algae/algal extracts in food, feed, pharmaceutical and cosmetics products. Offering a holistic view of the various applications, the book looks at the economic feasibility, market trends and considerations, and health hazards associated with algae for industrial applications. This important book: Provides a comprehensive overview of algal biomolecules and the role of emerging processing technologies Explores the potential biological and health benefits of algae and their applications in food, pharmaceuticals and cosmetic products Includes a current review of algal bioactives and processing technologies for food and ingredient manufacturers Contains contributions from leading academic and industrial experts Written for food scientists, allied researchers and professional food technologists, Recent Advances in Micro- and Macroalgal Processing: Food and Health Perspectives offers a guide to the novel processing and extraction techniques for exploring and harnessing the immense potential of algae.
This novel and informative book discusses the various aspects of seafood quality. The book is divided into 7 broad sections, each tackling a different aspect. The first section covers the general aspects relevant to the nutritional quality of the fish and the various extraction protocols for macro-/ micro-nutrients. The second section provides insights into handling and the principles of thermal and non-thermal processing techniques for commercially important fishery products. The quality standards and safety concerns in the seafood industry and consumption are discussed in this section. The freshness indices of the processed products including biochemical, microbiological and toxicological characteristics are also included. The third section discusses the physico-chemical characteristics and quality parameters of potable water/ ice. The fourth section includes the quality assessment of various toxicants related to seafood products. The fifth section deals with the specific aspects such as principle, instrument and procedures of conventional and novel analytical instruments relevant to the seafood industry. The sixth section deals with the seafood waste management including solid and liquid seafood wastes. Presently, there is a great awareness regarding environmental sustainable processing/ preservation techniques. The final chapter discusses the bioactive compounds from under-utilized marine sources showing pharmaceutical/ nutraceutical applications.
With an account of over 6.000 recent and 15.000 fossil species, phylum Bryozoa represents a quite large and important phylum of colonial filter feeders. This volume of the series Handbook of Zoology contains new findings on phylogeny, morphology and evolution that have significantly improved our knowledge and understanding of this phylum. It is a comprehensive book that will be a standard for many specialists but also newcomers to the field of bryozoology.