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The blood cold chain is a series of interconnected activities involving equipment, personnel and processes critical for the safe storage and transportation of blood from collection to transfusion. This publication contains information in relation to: storage and transportation of blood and blood components; blood storage equipment, relating to refrigerators, plasma freezers and platelet agitators; other blood cold chain devices; equipment installation; organising the cold blood chain; preventative maintenance, care and repair of equipment; monitoring and evaluation; and guidelines for the development of training programmes.
The safe storage and transportation of blood and blood products is an important part of strategy for blood safety. This publication provides minimum performance specifications and product informaation on equipment evaluated by WHO and also basic information on the blood cold chain and guidelines on its management.
This text helps readers to build a solid understanding of the key concepts in the management and operation of supply chains involving chilling, refrigeration or freezing. Emphasis is placed on environmental—particularly temperature—control as important in avoiding irreversible damage to product quality and safety and the resulting loss of profit and consumer confidence. The authors explain the important issues arising within the supply chain of perishable goods from production to consumption: topics that include planning and design, instrumentation and methods of implementation, and process monitoring and control. Reminding the student that cold supply chains are essential for the supply of products more various than foods, product-specific studies and examples are included for handling bananas and vaccines. The importance of product traceability and automation are highlighted. Cold Chain Management is a self-contained guide for graduate and final-year undergraduate students specializing in the study of supply chains, and their instructors. Researchers interested in logistics will find this book instructive when they wish to consider the particular problems associated with cold chains and anyone looking to begin a business in which refrigeration or freezing will be necessary will be well-served by reading this text.
Best Practices in Infection Prevention and Control: An International Perspective, Second Edition, a copublication of Joint Commission International and the Society for Healthcare Epidemiology of America (SHEA), is an essential infection prevention and control (IPC) resource for health care organizations. This fully updated edition provides thorough analysis of JCI's and other IPC requirements, as well as case studies, tips, and tools for increasing IPC compliance and patient safety.
"Blood transfusion is a life-saving intervention that has an essential role in patient management within health care systems. All Member States of the World Health Organization (WHO) endorsed World Health Assembly resolutions WHA28.72 (1) in 1975 and WHA58.13 (2) in 2005. These commit them to the provision of adequate supplies of safe blood and blood products that are accessible to all patients who require transfusion either to save their lives or promote their continuing or improving health." --Preface.
This book explores the economic and broader societal rationale for using unmanned aerial vehicle (UAV) or “drone†? technologies as a complement to the current transport and logistics systems in several use cases in East Africa. The specific use cases examined include medical goods deliveries, food aid delivery, land mapping and risk assessment, agriculture, and transport and energy infrastructure inspection. Across these applications, the case for using UAVs is examined within the context of logistics objectives—total operating costs, speed, availability, and flexibility—as well as human, or societal, objectives. In the public health use case, as more low- and middle-income countries explore opportunities to improve efficiency and performance in their health supply chains and diagnostics networks, they face myriad choices about how best to use UAVs to improve product availability and public health outcomes and to reach the last mile. The high-level findings from this analysis are that, if examining commodity categories individually and looking exclusively at costs, delivery with UAVs in general is still more expensive for most categories. Although the cost is still higher, the most cost-effective use case examples include the transport of laboratory samples to selected destinations and delivery of life-saving items and blood. However, “layering†? several use cases can provide efficiencies and cost savings by allocating fixed costs across a greater number of flights and maximizing capacity and time utilization. From the perspective of public decision-makers, the cost effectiveness of UAVs cannot be analyzed without looking at the public health benefits, which may be substantial. Drone application in the other use cases examined in this book, such as mapping, risk assessment, and agriculture, is relatively more common than cargo drone operations, and the existing pilot initiatives in East Africa have delivered impressive results for speed and quality (precision). Food aid delivery by drones is still mostly at a planning, rather than implementation, stage. Drone applications are rapidly evolving, and several use cases could gain impact and scale over the coming years.
The thalassemia syndromes are a diverse group of hereditary anemias caused by decreased or absent production of one type of globin chain. Genetic counseling, prenatal diagnosis, and newborn screening are all issues of importance in these inherited disorders. This book provides a comprehensive overview of thalassemia, including information on its mechanisms and treatment modalities. Chapters elucidate the mechanism of disordered synthesis of hemoglobin in thalassemia and present recent studies of the genetic mechanisms that underlie this abnormal biosynthetic process.