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A comprehensive and practical account of how to set up and run a successful IUI and ovulation induction program.
For many years, it has been known that pituitary gonadotropins are in control of menstrual cycle dynamics and ovulation. Over thirty years ago, the introduction of medications that were capable of inducing ovarian function through indirect or direct gonadotropin stimulation revolutionized the treatment of reproductive disorders in both men and women. This book covers all aspects of ovulation induction that a clinician needs to know including all known current stimulation protocols and induction strategies. It is directed at all gynaecologists, infertility professionals, both medical and paramedical including postgraduate students.
Ovarian Stimulation Protocols is a concise handbook that aims to deliver everything the reader needs to know for performing a risk-free ovarian stimulation for assisted reproductive technique (ART) and get a favorable outcome. Review of crucial issues such as the significance of monitoring ovarian stimulation, advantages and disadvantages of ovarian hyperstimulation versus minimal stimulation, and the use of various drug regimens and stimulation protocols for various patient sub-sets, will help clinicians in selecting the better or more appropriate protocols. The contributors of this book have leading scientific and clinical backgrounds, with years of experience to support their views. The book serves as a handy practical guide, targeting and settling clinical dilemma that ART practitioners commonly experience in their clinics, while providing a window to the newer developments. ​
The new edition of this infertility manual has been fully revised to provide clinicians with the latest advances in the diagnosis and management of infertility. Divided into seven sections, the book provides step by step guidance on each stage of the process, from initial examination and identifying the causes of infertility in both females and males, to ovarian stimulation and assisted reproduction techniques. The final section is dedicated to laboratory management covering topics such as follicular fluid screening and oocyte assessment, culture systems, and cryopreservation. The fourth edition includes new chapters on molecular mechanisms such as endometrial receptivity, and implantation; and current trends such as the embryoscope and assisted hatching. The comprehensive text is further enhanced by case studies, clinical photographs, diagrams, flowcharts and tables. Key points Fully revised, new edition providing latest advances in diagnosis and management of infertility Fourth edition features new chapters on molecular mechanisms and current trends Highly illustrated with clinical images, flowcharts and tables Previous edition (9788184486179) published in 2009
Over the past decade, there have been major advances in our understanding of ovarian physiology. These advances, together with the introduction of new medical technologies, have revolutionised the management of infertility. Patients may expect a pregnancy rate that is no different from that of normal fertile women of the same age, as a result of treatment. Moreover, new techniques of monitoring have greatly reduced the rate of treatment-induced complications such as multiple pregnancy and hyperstimulation. This book presents the current strategies of management for women whose infertility is caused by ovulatory disturbances. Detailed descriptions are given of the optimal method of assessing of an anovulatory woman, the selection of the appropriate treatment and the practical details of its administration. There is also a full discussion about the complications of the treatment and the strategies to avoid. The book is intended for all practising gynaecologists involved in the management of subfertile patients, in both the developing and the developed world.
Practical Guide to Ovulation Induction is considered a basis of success for the assisted reproductive technologies. There are several chemicals available for the same but the precise guidelines and understanding about these chemicals, their precise indications and side-effects are not fully understandable in most literature available. The authors have tried to cover each and every aspect of ovulation induction in this book including ovulation induction for intrauterine insemination and in vitro fertilization, in polycystic ovarian syndrome patients and also in poor responders, down regulation options, monitoring of the stimulated cycles, ovulation trigger and luteal support. It is a crisp, precise and a concise book covering the entire subject with clear understanding and a quick reference for busy practitioners too. Book jacket.
Manual of Ovulation Induction and Ovarian Stimulation Protocols encompasses all aspects of ovulation induction and current stimulation protocols in detail. This detailed text provides the reader with a reliable overview of the principles involved and the management required for ovulation induction in the treatment of infertility. This book is comprised of 68 chapters which cover the tailoring of ovarian stimulation regimens to a patient’s medical history and previous response to treatment. Both the clinical and sonographic findings in evaluating ovulatory function and dysfunction are discussed in detail. Methods for monitoring folliculogenesis, which in turn allows the ART specialist to accurately predict the number, as well as the timing of the high quality of oocyte retrieval, are discussed in detail. The book features discussion on basic and clinical research evidence, which is accumulating to propose the future use of recombinant FSH and LH in order to achieve controlled ovarian stimulation. The inclusion of the most current research in this second edition makes Manual of Ovulation Induction and Ovarian Stimulation Protocols a valuable book for gynaecologists, infertility specialists, and healthcare professionals dealing with IVF. Key Points Includes current research and future implications 60+ full colour images and illustrations New edition. First published 2005
One of the world's most widely read gynecology texts for nearly 50 years, Speroff ’s Clinical Gynecologic Endocrinology and Infertility provides a complete explanation of the female endocrine system and offers practical guidance for evaluation and treatment of common disorders. In this fully revised ninth edition, the editorial and author team from Yale School of Medicine have assumed the reins of Dr. Speroff’s landmark work, retaining the clear, concise writing style and illustrations that clarify and explain complex concepts. This classic text remains indispensable for students, residents, and clinicians working in reproductive endocrinology and infertility, bringing readers up to date with recent advances that have occurred in this fast-changing field.
The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
VOLUME 1: INFERTILITY SECTION 1: ANATOMY AND PHYSIOLOGY 1. Anatomy of the Reproductive System 2. Regulation and Physiology of Menstrual Cycle 3. Oogenesis and Folliculogenesis 4. Spermatogenesis 5. Fertilization and Embryogenesis 6. Implantation 7. Embryo Endometrial Crosstalk and Endometrial Receptivity SECTION 2: REPRODUCTIVE ENDOCRINOLOGY 8. Synthesis and Metabolism of Steroid Hormones 9. Puberty and Aberrations 10. Amenorrhea 11. Endocrine Disorders Affecting Reproduction 12. Hirsutism 13. Luteal Phase Defect 14. Anovulation 15. Declining Fertility SECTION 3: COMBINED TOPICS 16. Evaluation of Infertility 17. Immunology and Infertility 18. Cytogenetics and Subfertility 19. Obesity and Infertility 20. Unexplained Infertility 21. Fertility Preservation 22. Counseling in Infertility 23. Assisted Reproductive Technology in Patients with Chronic Medical Disorders SECTION 4: MALE INFERTILITY 24. Etiopathogenesis of Male Infertility 25. Clinical and Endocrinological Evaluation of Infertile Male 26. Sexual Dysfunction in Male Infertility 27. Ultrasound in Male Infertility 28. Medical Management of Male Infertility 29. Azoospermia: Evaluation and Management 30. Varicocele and Infertility 31. Spinal Cord Injuries and Male Infertility 32. Algorithms for Genetic Evaluation of Infertile Males SECTION 5: FEMALE FACTOR INFERTILITY 33. Uterine Factors in Infertility 34. Tubal Factors in Infertility 35. Infections and Infertility 36. Tuberculosis and Infertility 37. Sonoendocrinology and Cycle Monitoring Assisted Reproduction Technology 38. Transvaginal Ultrasound and Doppler in Infertility 39. Polycystic Ovary Syndrome 40. Assessment of Ovarian Reserve 41. Endometriosis 42. Endoscopy in Infertility 43. Reconstructive Surgeries Enhancing Fertility SECTION 6: INTRAUTERINE INSEMINATION 44. Intrauterine Insemination 45. Optimizing Success in Intrauterine Insemination SECTION 7: OVARIAN STIMULATION 46. Drugs for Ovarian Stimulation 47. Ovulation Induction and Ovarian Stimulation Protocols 48. Role of Adjuvants in Ovarian Stimulation 49. Gonadotropinreleasing Hormone Analogs 50. Monitoring of Ovarian Stimulation 51. Ovulation Trigger 52. Individualized Controlled Ovarian Stimulation 53. In Vitro Fertilization Lite 54. Role of Luteinizing Hormone in Ovarian Stimulation 55. Anesthesia in Assisted Reproductive Techniques 56. Oocyte Retrieval. 57. Embryo Transfer 58. Troubleshooting in Assisted Reproductive Technology 59. Luteal Phase Support SECTION 8: DILEMMA IN ART 60. Poor Responder 61. Recurrent Implantation Failure 62. Empty Follicle Syndrome 63. Role of Aneuploidy Screening in Preimplantation Embryos 64. Preimplantation Genetic Testing of Embryos 65. Epigenetics and Assisted Reproductive Technology SECTION 9: COMPLICATIONS IN ART 66. Ovarian Hyperstimulation Syndrome 67. Ectopic Pregnancy 68. Multipleorder Births SECTION 10: THIRD PARTY REPRODUCTION 69. Oocyte and Sperm Donation 70. Surrogacy in Assisted Reproductive Technology 71. Assisted Reproductive Technology Guidelines 72. Adoption 73. LGBTQ and Fertility 74. Transgender Population and Fertility SECTION 11: OUTCOME FOLLOWING ASSISTED REPRODUCTIVE TECHNIQUE 75. Maternal and Fetal Outcomes Following Assisted Reproductive Technique 76. Early Pregnancy Scan 77. Recurrent Pregnancy Loss: From Diagnostic Dilemmas to Clinical Decisions SECTION 12: RECENT ADVANCES 78. Bioengineered Human Endometrium In Vitro. 79. Recent Trends in A...