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Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
NEW YORK TIMES BESTSELLER • From the author of the #1 New York Times bestseller On Tyranny comes an impassioned condemnation of America's pandemic response and an urgent call to rethink health and freedom. On December 29, 2019, historian Timothy Snyder fell gravely ill. Unable to stand, barely able to think, he waited for hours in an emergency room before being correctly diagnosed and rushed into surgery. Over the next few days, as he clung to life and the first light of a new year came through his window, he found himself reflecting on the fragility of health, not recognized in America as a human right but without which all rights and freedoms have no meaning. And that was before the pandemic. We have since watched American hospitals, long understaffed and undersupplied, buckling under waves of ill patients. The federal government made matters worse through willful ignorance, misinformation, and profiteering. Our system of commercial medicine failed the ultimate test, and thousands of Americans died. In this eye-opening cri de coeur, Snyder traces the societal forces that led us here and outlines the lessons we must learn to survive. In examining some of the darkest moments of recent history and of his own life, Snyder finds glimmers of hope and principles that could lead us out of our current malaise. Only by enshrining healthcare as a human right, elevating the authority of doctors and medical knowledge, and planning for our children’s future can we create an America where everyone is truly free.
"Yes, women are the greatest evil Zeus has made, and men are bound to them hand and foot with impossible knots by God."—Semonides, seventh century B.C. Men put women on a pedestal to worship them from afar—and to take better aim at them for the purpose of derision. Why is this paradoxical response to women so widespread, so far-reaching, so all-pervasive? Misogyny, David D. Gilmore suggests, is best described as a male malady, as it has always been a characteristic shared by human societies throughout the world. Misogyny: The Male Malady is a comprehensive historical and anthropological survey of woman-hating that casts new light on this age-old bias. The turmoil of masculinity and the ugliness of misogyny have been well documented in different cultures, but Gilmore's synoptic approach identifies misogyny in a variety of human experiences outside of sex and marriage and makes a fresh and enlightening contribution toward understanding this phenomenon. Gilmore maintains that misogyny is so widespread and so pervasive among men that it must be at least partly psychogenic in origin, a result of identical experiences in the male developmental cycle, rather than caused by the environment alone. Presenting a wealth of compelling examples—from the jungles of New Guinea to the boardrooms of corporate America—Gilmore shows that misogynistic practices occur in hauntingly identical forms. He asserts that these deep and abiding male anxieties stem from unresolved conflicts between men's intense need for and dependence upon women and their equally intense fear of that dependence. However, misogyny, according to Gilmore, is also often supported and intensified by certain cultural realities, such as patrilineal social organization; kinship ideologies that favor fraternal solidarity over conjugal unity; chronic warfare, feuding, or other forms of intergroup violence; and religious orthodoxy or asceticism. Gilmore is in the end able to offer steps toward the discovery of antidotes to this irrational but global prejudice, providing an opportunity for a lasting cure to misogyny and its manifestations.
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An intellectual history of scurvy in the eighteenth century Scurvy—a disease usually associated with long stretches of maritime travel—generated extraordinary sensations. Eyes dazzled, skin was morbidly sensitive, emotions veered between disgust and delight. In this book, Jonathan Lamb presents an intellectual history of scurvy unlike any other, probing its cultural impact during the eighteenth-century age of geographic and scientific discovery. Drawing on historical accounts from scientists and voyagers as well as major literary works, Lamb explains the medical knowledge surrounding scurvy and the debates about its cause, prevention, and attempted cures. He argues that a “culture” of scurvy arose in the colony of Australia, which was prey to the disease in its early years, and identifies a literature of scurvy in the works of such figures as Herman Melville, Samuel Taylor Coleridge, Francis Bacon, and Jonathan Swift. Masterful and illuminating, Scurvy shows how eighteenth-century journeys of discovery not only ventured outward to the ends of the earth, but were also an inward voyage into the realms of sensation and passion.
A sweeping global history that looks beyond European urban centers to show how slavery, colonialism, and war propelled the development of modern medicine. Most stories of medical progress come with ready-made heroes. John Snow traced the origins of LondonÕs 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence NightingaleÕs contributions to the care of soldiers in the Crimean War revolutionized medical hygiene, transforming hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge, especially when it comes to the science of infectious disease. Reexamining the foundations of modern medicine, Jim Downs shows that the study of infectious disease depended crucially on the unrecognized contributions of nonconsenting subjectsÑconscripted soldiers, enslaved people, and subjects of empire. Plantations, slave ships, and battlefields were the laboratories in which physicians came to understand the spread of disease. Military doctors learned about the importance of air quality by monitoring Africans confined to the bottom of slave ships. Statisticians charted cholera outbreaks by surveilling Muslims in British-dominated territories returning from their annual pilgrimage. The field hospitals of the Crimean War and the US Civil War were carefully observed experiments in disease transmission. The scientific knowledge derived from discarding and exploiting human life is now the basis of our ability to protect humanity from epidemics. Boldly argued and eye-opening, Maladies of Empire gives a full account of the true price of medical progress.
Against the backdrop of unprecedented concern for the future of health care, 'The Cambridge History of Medicine' surveys the rise of medicine in the West from classical times to the present. Covering both the social and scientific history of medicine, this volume traces the chronology of key developments and events.