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This book is a highly readable and entertaining account of the co-evolution of the patent system and the life science industries since the mid-19th century. The pharmaceutical industries have their origins in advances in synthetic chemistry and in natural products research. Both approaches to drug discovery and business have shaped patent law, as have the lobbying activities of the firms involved and their supporters in the legal profession. In turn, patent law has impacted on the life science industries. Compared to the first edition, which told this story for the first time, the present edition focuses more on specific businesses, products and technologies, including Bayer, Pfizer, GlaxoSmithKline, aspirin, penicillin, monoclonal antibodies and polymerase chain reaction. Another difference is that this second edition also looks into the future, addressing new areas such as systems biology, stem cell research, and synthetic biology, which promises to enable scientists to OC inventOCO life forms from scratch.
This text examines the international agreements governing trade in genetic resources - crucial resources for world agriculture, food security and large industries such as pharmaceuticals. Intellectual Property Rights (IPRs) in these resources are critical for those involved in the trade, including industry and developing countries. The book analyzes the Convention on Biological Diversity (CBD), World Trade Organization agreements and other agreements. It explains how they can be integrated into an equitable training regime.
This volume examines scientific practice through studies of research tools in an array of twentieth-century life sciences. The contributors draw upon and extend the multidisciplinary perspectives in current science studies to understand the processes through which scientific researchers constructed the right--and, in some cases, the wrong--tools for the job. The articles portray the crafting or accessing of specific materials, techniques, instruments, models, funds, and work arrangements involved in doing scientific work. They demonstrate the historical and local contingencies of scientific problem construction and solving by highlighting the articulation between the tools and jobs. Indeed, the very "rightness" of the tools is contingently constructed, maintained, lost, and refashioned. The cases examined include evolutionary biology laboratory systems (James R. Griesemer), the plasmid prep procedure in molecular biology (Kathleen Jordan and Michael Lynch), models in the human ecology of African pastoralists (Peter Taylor), the micromanometer in metabolic studies (Frederic L. Holmes), genetics research and the role played by Planaria (Gregg Mitman and Anne Fausto-Sterling) and by corn (Barbara A. Kimmelman), quantitative data in field biology (Yrj Haila), taxidermy in natural history (Susan Leigh Star), technical standardization in bacteriology (Patricia Peck Gossell), and the discipline of immunology as the tool for stabilizing conceptual definitions in the field (Peter Keating, Alberto Cambrosio, and Michael Mackenzie). Originally published in 1992. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Rich with archival detail and compelling characters, Life on Display uses the history of biological exhibitions to analyze museums’ shifting roles in twentieth-century American science and society. Karen A. Rader and Victoria E. M. Cain chronicle profound changes in these exhibitions—and the institutions that housed them—between 1910 and 1990, ultimately offering new perspectives on the history of museums, science, and science education. Rader and Cain explain why science and natural history museums began to welcome new audiences between the 1900s and the 1920s and chronicle the turmoil that resulted from the introduction of new kinds of biological displays. They describe how these displays of life changed dramatically once again in the 1930s and 1940s, as museums negotiated changing, often conflicting interests of scientists, educators, and visitors. The authors then reveal how museum staffs, facing intense public and scientific scrutiny, experimented with wildly different definitions of life science and life science education from the 1950s through the 1980s. The book concludes with a discussion of the influence that corporate sponsorship and blockbuster economics wielded over science and natural history museums in the century’s last decades. A vivid, entertaining study of the ways science and natural history museums shaped and were shaped by understandings of science and public education in the twentieth-century United States, Life on Display will appeal to historians, sociologists, and ethnographers of American science and culture, as well as museum practitioners and general readers.
Recent scholarship has revealed that pioneering Victorian scientists endeavored through voluminous writing to raise public interest in science and its implications. But it has generally been assumed that once science became a profession around the turn of the century, this new generation of scientists turned its collective back on public outreach. Science for All debunks this apocryphal notion. Peter J. Bowler surveys the books, serial works, magazines, and newspapers published between 1900 and the outbreak of World War II to show that practicing scientists were very active in writing about their work for a general readership. Science for All argues that the social environment of early twentieth-century Britain created a substantial market for science books and magazines aimed at those who had benefited from better secondary education but could not access higher learning. Scientists found it easy and profitable to write for this audience, Bowler reveals, and because their work was seen as educational, they faced no hostility from their peers. But when admission to colleges and universities became more accessible in the 1960s, this market diminished and professional scientists began to lose interest in writing at the nonspecialist level. Eagerly anticipated by scholars of scientific engagement throughout the ages, Science for All sheds light on our own era and the continuing tension between science and public understanding.
Many of the scientific breakthroughs of the twentieth century were first reported in the journal Nature. A Century of Nature brings together in one volume Nature's greatest hits—reproductions of seminal contributions that changed science and the world, accompanied by essays written by leading scientists (including four Nobel laureates) that provide historical context for each article, explain its insights in graceful, accessible prose, and celebrate the serendipity of discovery and the rewards of searching for needles in haystacks.
Explores how science and technology have helped to shape America during the twentieth century in areas such as agriculture, transportation, medicine, and education.
Refiguring Life begins with the history of genetics and embryology, showing how discipline-based metaphors have directed scientists' search for evidence. Keller continues with an exploration of the border traffic between biology and physics, focusing on the question of life and the law of increasing entropy. In a final section she traces the impact of new metaphors, born of the computer revolution, on the course of biological research. Keller shows how these metaphors began as objects of contestation between competing visions of the life sciences, how they came to be recast and appropriated by already established research agendas, and how in the process they ultimately came to subvert those same agendas. Refiguring Life explains how the metaphors and machinery of research are not merely the products of scientific discovery but actually work together to map out the territory along which new metaphors and machines can be constructed. Through their dynamic interaction, Keller points out, they define the realm of the possible in science. Drawing on a remarkable spectrum of theoretical work ranging from Schroedinger to French psychoanalyst Jacques Lacan, Refiguring Life fuses issues already prominent in the humanities and social sciences with those in the physical and natural sciences, transgressing disciplinary boundaries to offer a broad view of the natural sciences as a whole. Moving gracefully from genetics to embryology, from physics to biology, from cyberscience to molecular biology, Evelyn Fox Keller demonstrates that scientific inquiry cannot pretend to stand apart from the issues and concerns of the larger society in which it exists.
Humorous, illustrated novel by the “father of science fiction illustration”.