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Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.
A philosopher refutes our culturally embedded acceptance of death, arguing instead for the desirability of anti-aging science and radical life extension. Ingemar Patrick Linden’s central claim is that death is evil. In this first comprehensive refutation of the most common arguments in favor of human mortality, he writes passionately in favor of antiaging science and radical life extension. We may be on the cusp of a new human condition where scientists seek to break through the arbitrarily set age limit of human existence to address aging as an illness that can be cured. The book, however, is not about the science and technology of life extension but whether we should want more life. For Linden, the answer is a loud and clear “yes.” The acceptance of death is deeply embedded in our culture. Linden examines the views of major philosophical voices of the past, whom he calls “death’s ardent advocates.” These include the Buddha, Socrates, Plato, Lucretius, and Montaigne. All have taught what he calls “the Wise View,” namely, that we should not fear death. After setting out his case against death, Linden systematically examines each of the accepted arguments for death—that aging and death are natural, that death is harmless, that life is overrated, that living longer would be boring, and that death saves us from overpopulation. He concludes with a “dialogue concerning the badness of human mortality.” Though Linden acknowledges that The Case Against Death is a negative polemic, he also defends it as optimistic, in that the badness of death is a function of the goodness of life.
A comprehensive overview of managing and assessing safety and functionality of ageing offshore structures and pipelines A significant proportion, estimated at over 50%, of the worldwide infrastructure of offshore structures and pipelines is in a life extension phase and is vulnerable to ageing processes. This book captures the central elements of the management of ageing offshore structures and pipelines in the life extension phase. The book gives an overview of: the relevant ageing processes and hazards; how ageing processes are managed through the life cycle, including an overview of structural integrity management; how an engineer should go about assessing a structure that is to be operated beyond its original design life, and how ageing can be mitigated for safe and effective continued operation. Key Features: Provides an understanding of ageing processes and how these can be mitigated. Applies engineering methods to ensure that existing structures can be operated longer rather than decommissioned unduly prematurely. Helps engineers performing these tasks in both evaluating the existing structures and maintaining ageing structures in a safe manner. The book gives an updated summary of current practice and research on the topic of the management of ageing structures and pipelines in the life extension phase but also meets the needs of structural engineering students and practicing offshore and structural engineers in oil & gas and engineering companies. In addition, it should be of value to regulators of the offshore industry.
An innovative resource for materials properties, their evaluation, and industrial applications The Handbook of Materials Selection provides information and insight that can be employed in any discipline or industry to exploit the full range of materials in use today-metals, plastics, ceramics, and composites. This comprehensive organization of the materials selection process includes analytical approaches to materials selection and extensive information about materials available in the marketplace, sources of properties data, procurement and data management, properties testing procedures and equipment, analysis of failure modes, manufacturing processes and assembly techniques, and applications. Throughout the handbook, an international roster of contributors with a broad range of experience conveys practical knowledge about materials and illustrates in detail how they are used in a wide variety of industries. With more than 100 photographs of equipment and applications, as well as hundreds of graphs, charts, and tables, the Handbook of Materials Selection is a valuable reference for practicing engineers and designers, procurement and data managers, as well as teachers and students.
In this book two of the world's leading medical researchers explains how melatonin works. It already prevents jet-lag and research suggests it controls the aging process, fights disease, boosts the immune system, lowers cholesterol & relieves stress.
Discusses various aspects of aging and includes suggestions on how to slow the aging process and improve your health.
A leading scientist and an expert on human longevity explain how new discoveries in the fields of genomics, biotechnology, and nanotechnology could radically extend the human life expectancy and enhance physical and mental abilities, and introduce a cutting-edge program designed to enhance the immune system and slow the aging process on a cellular level. Reprint.
When Dr. Michael A. Smith hears this common question, his answer is always a resounding "Yes" In The Supplement Pyramid, Dr. Smith covers the many reasons why even the healthiest diets fall short in terms of supplying the optimal amount of nutrients we need not just to survive, but also to thrive. With such a staggering amount of supplement choices on the market, it's hard to know where to start. The Supplement Pyramid provides the road map. With its three-tiered plan-foundational, personalization, and optimization levels-The Supplement Pyramid helps you design a nutritional regimen to meet your personal needs. Step-by-step instructions and detailed medical quizzes, along with useful information about blood testing, will help you develop an ideal personalized menu of supplements from which to choose. Knowing which supplements to take is only half the battle. Purchasing high-quality products is essential for success, and therefore The Supplement Pyramid covers all of the information you need to know to be sure you are making the best investment in your health. Written in easy-to-understand language and providing a wealth of vital information, this book puts all the questions to rest so you can move toward an optimal personalized supplement regimen. Book jacket.
Over 19,000 total pages ... Public Domain U.S. Government published manual: Numerous illustrations and matrices. Published in the 1990s and after 2000. TITLES and CONTENTS: ELECTRICAL SCIENCES - Contains the following manuals: Electrical Science, Vol 1 - Electrical Science, Vol 2 - Electrical Science, Vol 3 - Electrical Science, Vol 4 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 1 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 2 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 3 - Instrumentation And Control, Vol 1 - Instrumentation And Control, Vol 2 Mathematics, Vol 1 - Mathematics, Vol 2 - Chemistry, Vol 1 - Chemistry, Vol 2 - Engineering Symbology, Prints, And Drawings, Vol 1 - Engineering Symbology, Prints, And Drawings, Vol 2 - Material Science, Vol 1 - Material Science, Vol 2 - Mechanical Science, Vol 1 - Mechanical Science, Vol 2 - Nuclear Physics And Reactor Theory, Vol 1 - Nuclear Physics And Reactor Theory, Vol 2. CLASSICAL PHYSICS - The Classical Physics Fundamentals includes information on the units used to measure physical properties; vectors, and how they are used to show the net effect of various forces; Newton's Laws of motion, and how to use these laws in force and motion applications; and the concepts of energy, work, and power, and how to measure and calculate the energy involved in various applications. * Scalar And Vector Quantities * Vector Identification * Vectors: Resultants And Components * Graphic Method Of Vector Addition * Component Addition Method * Analytical Method Of Vector Addition * Newton's Laws Of Motion * Momentum Principles * Force And Weight * Free-Body Diagrams * Force Equilibrium * Types Of Force * Energy And Work * Law Of Conservation Of Energy * Power – ELECTRICAL SCIENCE: The Electrical Science Fundamentals Handbook includes information on alternating current (AC) and direct current (DC) theory, circuits, motors, and generators; AC power and reactive components; batteries; AC and DC voltage regulators; transformers; and electrical test instruments and measuring devices. * Atom And Its Forces * Electrical Terminology * Units Of Electrical Measurement * Methods Of Producing Voltage (Electricity) * Magnetism * Magnetic Circuits * Electrical Symbols * DC Sources * DC Circuit Terminology * Basic DC Circuit Calculations * Voltage Polarity And Current Direction * Kirchhoff's Laws * DC Circuit Analysis * DC Circuit Faults * Inductance * Capacitance * Battery Terminology * Battery Theory * Battery Operations * Types Of Batteries * Battery Hazards * DC Equipment Terminology * DC Equipment Construction * DC Generator Theory * DC Generator Construction * DC Motor Theory * Types Of DC Motors * DC Motor Operation * AC Generation * AC Generation Analysis * Inductance * Capacitance * Impedance * Resonance * Power Triangle * Three-Phase Circuits * AC Generator Components * AC Generator Theory * AC Generator Operation * Voltage Regulators * AC Motor Theory * AC Motor Types * Transformer Theory * Transformer Types * Meter Movements * Voltmeters * Ammeters * Ohm Meters * Wattmeters * Other Electrical Measuring Devices * Test Equipment * System Components And Protection Devices * Circuit Breakers * Motor Controllers * Wiring Schemes And Grounding THERMODYNAMICS, HEAT TRANSFER AND FLUID FUNDAMENTALS. The Thermodynamics, Heat Transfer, and Fluid Flow Fundamentals Handbook includes information on thermodynamics and the properties of fluids; the three modes of heat transfer - conduction, convection, and radiation; and fluid flow, and the energy relationships in fluid systems. * Thermodynamic Properties * Temperature And Pressure Measurements * Energy, Work, And Heat * Thermodynamic Systems And Processes * Change Of Phase * Property Diagrams And Steam Tables * First Law Of Thermodynamics * Second Law Of Thermodynamics * Compression Processes * Heat Transfer Terminology * Conduction Heat Transfer * Convection Heat Transfer * Radiant Heat Transfer * Heat Exchangers * Boiling Heat Transfer * Heat Generation * Decay Heat * Continuity Equation * Laminar And Turbulent Flow * Bernoulli's Equation * Head Loss * Natural Circulation * Two-Phase Fluid Flow * Centrifugal Pumps INSTRUMENTATION AND CONTROL. The Instrumentation and Control Fundamentals Handbook includes information on temperature, pressure, flow, and level detection systems; position indication systems; process control systems; and radiation detection principles. * Resistance Temperature Detectors (Rtds) * Thermocouples * Functional Uses Of Temperature Detectors * Temperature Detection Circuitry * Pressure Detectors * Pressure Detector Functional Uses * Pressure Detection Circuitry * Level Detectors * Density Compensation * Level Detection Circuitry * Head Flow Meters * Other Flow Meters * Steam Flow Detection * Flow Circuitry * Synchro Equipment * Switches * Variable Output Devices * Position Indication Circuitry * Radiation Detection Terminology * Radiation Types * Gas-Filled Detector * Detector Voltage * Proportional Counter * Proportional Counter Circuitry * Ionization Chamber * Compensated Ion Chamber * Electroscope Ionization Chamber * Geiger-Müller Detector * Scintillation Counter * Gamma Spectroscopy * Miscellaneous Detectors * Circuitry And Circuit Elements * Source Range Nuclear Instrumentation * Intermediate Range Nuclear Instrumentation * Power Range Nuclear Instrumentation * Principles Of Control Systems * Control Loop Diagrams * Two Position Control Systems * Proportional Control Systems * Reset (Integral) Control Systems * Proportional Plus Reset Control Systems * Proportional Plus Rate Control Systems * Proportional-Integral-Derivative Control Systems * Controllers * Valve Actuators MATHEMATICS The Mathematics Fundamentals Handbook includes a review of introductory mathematics and the concepts and functional use of algebra, geometry, trigonometry, and calculus. Word problems, equations, calculations, and practical exercises that require the use of each of the mathematical concepts are also presented. * Calculator Operations * Four Basic Arithmetic Operations * Averages * Fractions * Decimals * Signed Numbers * Significant Digits * Percentages * Exponents * Scientific Notation * Radicals * Algebraic Laws * Linear Equations * Quadratic Equations * Simultaneous Equations * Word Problems * Graphing * Slopes * Interpolation And Extrapolation * Basic Concepts Of Geometry * Shapes And Figures Of Plane Geometry * Solid Geometric Figures * Pythagorean Theorem * Trigonometric Functions * Radians * Statistics * Imaginary And Complex Numbers * Matrices And Determinants * Calculus CHEMISTRY The Chemistry Handbook includes information on the atomic structure of matter; chemical bonding; chemical equations; chemical interactions involved with corrosion processes; water chemistry control, including the principles of water treatment; the hazards of chemicals and gases, and basic gaseous diffusion processes. * Characteristics Of Atoms * The Periodic Table * Chemical Bonding * Chemical Equations * Acids, Bases, Salts, And Ph * Converters * Corrosion Theory * General Corrosion * Crud And Galvanic Corrosion * Specialized Corrosion * Effects Of Radiation On Water Chemistry (Synthesis) * Chemistry Parameters * Purpose Of Water Treatment * Water Treatment Processes * Dissolved Gases, Suspended Solids, And Ph Control * Water Purity * Corrosives (Acids And Alkalies) * Toxic Compound * Compressed Gases * Flammable And Combustible Liquids ENGINEERING SYMBIOLOGY. The Engineering Symbology, Prints, and Drawings Handbook includes information on engineering fluid drawings and prints; piping and instrument drawings; major symbols and conventions; electronic diagrams and schematics; logic circuits and diagrams; and fabrication, construction, and architectural drawings. * Introduction To Print Reading * Introduction To The Types Of Drawings, Views, And Perspectives * Engineering Fluids Diagrams And Prints * Reading Engineering P&Ids * P&Id Print Reading Example * Fluid Power P&Ids * Electrical Diagrams And Schematics * Electrical Wiring And Schematic Diagram Reading Examples * Electronic Diagrams And Schematics * Examples * Engineering Logic Diagrams * Truth Tables And Exercises * Engineering Fabrication, Construction, And Architectural Drawings * Engineering Fabrication, Construction, And Architectural Drawing, Examples MATERIAL SCIENCE. The Material Science Handbook includes information on the structure and properties of metals, stress mechanisms in metals, failure modes, and the characteristics of metals that are commonly used in DOE nuclear facilities. * Bonding * Common Lattice Types * Grain Structure And Boundary * Polymorphism * Alloys * Imperfections In Metals * Stress * Strain * Young's Modulus * Stress-Strain Relationship * Physical Properties * Working Of Metals * Corrosion * Hydrogen Embrittlement * Tritium/Material Compatibility * Thermal Stress * Pressurized Thermal Shock * Brittle Fracture Mechanism * Minimum Pressurization-Temperature Curves * Heatup And Cooldown Rate Limits * Properties Considered * When Selecting Materials * Fuel Materials * Cladding And Reflectors * Control Materials * Shielding Materials * Nuclear Reactor Core Problems * Plant Material Problems * Atomic Displacement Due To Irradiation * Thermal And Displacement Spikes * Due To Irradiation * Effect Due To Neutron Capture * Radiation Effects In Organic Compounds * Reactor Use Of Aluminum MECHANICAL SCIENCE. The Mechanical Science Handbook includes information on diesel engines, heat exchangers, pumps, valves, and miscellaneous mechanical components. * Diesel Engines * Fundamentals Of The Diesel Cycle * Diesel Engine Speed, Fuel Controls, And Protection * Types Of Heat Exchangers * Heat Exchanger Applications * Centrifugal Pumps * Centrifugal Pump Operation * Positive Displacement Pumps * Valve Functions And Basic Parts * Types Of Valves * Valve Actuators * Air Compressors * Hydraulics * Boilers * Cooling Towers * Demineralizers * Pressurizers * Steam Traps * Filters And Strainers NUCLEAR PHYSICS AND REACTOR THEORY. The Nuclear Physics and Reactor Theory Handbook includes information on atomic and nuclear physics; neutron characteristics; reactor theory and nuclear parameters; and the theory of reactor operation. * Atomic Nature Of Matter * Chart Of The Nuclides * Mass Defect And Binding Energy * Modes Of Radioactive Decay * Radioactivity * Neutron Interactions * Nuclear Fission * Energy Release From Fission * Interaction Of Radiation With Matter * Neutron Sources * Nuclear Cross Sections And Neutron Flux * Reaction Rates * Neutron Moderation * Prompt And Delayed Neutrons * Neutron Flux Spectrum * Neutron Life Cycle * Reactivity * Reactivity Coefficients * Neutron Poisons * Xenon * Samarium And Other Fission Product Poisons * Control Rods * Subcritical Multiplication * Reactor Kinetics * Reactor
The first International Conference on Ageing Studies and Lifetime Extension of Materials was held on th July 12-14 , 1999 at St. Catherine's College, Oxford, United Kingdom. Over 230 delegates attended during the three days and heard nearly ninety papers, together with over thirty poster presentations. Sixteen of these papers were keynotes from invited speakers eminent in their field of research. The proceedings were organised into six separate sessions: observation and understanding of real-time and accelerated ageing; experimental techniques; modelling and theoretical studies; lifetime prediction and validation; lifetime extension; and material design for ageing. In doing this, it was hoped to cover most issues of scientific concern inthefield ofmaterials ageing. One important aspect was that the conference did not concentrateon any particular group or type ofmaterial; rather the aim was to attract contributions from workers engaged in ageing studies with as wide a range of materials as possible. In this way, it was hoped that delegates could interactwith and learnfrom those whom they perhapswould not normally come across and that metallurgists could learn from polymer scientists, ceramicists could talk to modellers, and so on, in this important field. A read through the diverse papers contained within these proceedings will confirm that this aim was happily satisfied. Why hold such a meeting? In the modem world, engineered systems are expected to last longer.