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Since its introduction 52 years ago, Leksell radiosurgery has become a widely applied technique for the management of a diverse group of vascular, neoplastic, and functional disorders. This publication presents an update on state-of-the-art radiosurgery technology, including outcomes, by the pioneers in the field. Experts have contributed chapters on various topics. They provide a history of the development of Leksell Gamma Knife and its evolution from frame-based to the inclusion of mask-based radiosurgery in the latest Gamma Knife model. For beginners, there is valuable information related to imaging, quality assurance, patient care, anesthesia, and regulatory requirements. Advance users will appreciate the summary of the long-term outcome of important indications. Additional chapters on cavernous malformation, orbital, uveal, and ocular disorders clarify the role of radiosurgery. This book is a concise overview for physicians interested in radiosurgery. It will be of great value to neurosurgeons, radiation oncologists, and medical physicists concerned with learning about the indications of radiosurgery.
This publication aims to give comprehensive information on the methods of gamma knife radiosurgery and the results of treatment of the most frequent diagnoses using radiosurgery. A summarisation of existing knowledge and results obtained in gamma knife radiosurgery world-wide is based on experience with treatment of more than 13,500 patients over 20 years at Na Homolce Hospital, Prague. Besides detailing the basic data of Leksell gamma knife radiosurgery, this book also provides thorough technical description of former and existing gamma knife models, basic physics principles of gamma knife radiosurgery, calibration and quality assurance as well as standardised treatment procedures. The book is primarily intended for physicians, who, together with the patient decide on the most appropriate methods of treatment for each diagnosis. The publication can be also helpful to medical physicists who are involved in gamma knife radiosurgery and responsible for its calibration and quality assurance. Finally, it is also intended for patients who are looking for, if necessary, more comprehensive information on the radiosurgical treatment method for tumours and other brain disorders.
In this third edition of Intracranial Stereotactic Radiosurgery, Drs. Sheehan and Lunsford provide an updated assessment of the practice of stereotactic radiosurgery. Topics include benign and malignant tumors, cerebrovascular abnormalities, and functional disorders. Several new topics are now included and focus on immunotherapy, hypofractionation, and repeat radiosurgery. Each chapter contains key figures and tables to illustrate the critical concepts of the work. Contributors to the book represent many of the most prestigious stereotactic radiosurgery centers across the world. This book is comprised of 36 chapters and represents a comprehensive update to prior editions. It is intended to be a readable, credible, and accessible reference on stereotactic radiosurgery. Editors Jason Sheehan, MD, PhD, FACS, FAANS, is the Vice Chair and Harrison Distinguished Professor of Neurological Surgery at the University of Virginia (UVA). He also serves as the Neurosciences Service Line Director at UVA. Dr. Sheehan is the current chair of the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors. He serves as the Editor-In-Chief of the Journal of Neuro-Oncology. L. Dade Lunsford, MD, serves as the Lars Leksell Professor and Distinguished Professor at the Department of Neurological Surgery at the University of Pittsburgh. He is also director of the Center for Image-Guided Neurosurgery at the University of Pittsburgh Medical Center and an internationally recognized authority on stereotactic surgery, radiosurgery, and minimally invasive surgery. He has authored or coauthored more than 1,000 scientific reports and 16 books.
The History of the Gamma Knife presents the evolution of concepts and technology which ended in the production of the modern Gamma Knife. The story starts before the Second World War and links pioneers in Berkeley and Sweden. To the best of the author's belief it is the first detailed, factually accurate account of the development of this important therapeutic method. - The author has been involved in Gamma Knife surgery since the early days and has written 3 books and many papers on the topic - The author is fluent in Scandinavian languages and knows the original pioneers in the field and has consulted with them to ensure the story is accurate - The book is written in an informal easy to read style - The book fills a vacuum in the literature. There are many short accounts of a few pages but no hopefully definitive account of the story of the Gamma Knife. Also these short accounts all too often contain errors which hopefully are absent from the current text
LINAC and Gamma Knife Radiosurgery is the first book on radiosurgery which presents together both Gamma Knife and linear accelerator (LINAC) radiosurgical techniques for various pathologies. Divided into three sections, LINAC and Gamma Knife Radiosurgery addresses: The fundamentals of stereotactic radiosurgery, including historical perspectives, basic principles of radiation physics and biology, principles and techniques of Gamma Knife and LINAC radiosurgery,software and dose planning, fractionation, proton-beam radiation therapy, clinical and histological aspects of radionecrosis and informed consent issues The clinical applications and results of both Gamma Knife and LINAC radiosurgery for vascular malformations, brain metastases, primary brain tumors, meningiomas, schwannomas and pituitary tumors Work in progress: clinical applications for pain, epilepsy and movement disorders, and future directions and new frontiers in radiosurgery LINAC and Gamma Knife Radiosurgery provides the reader with the hands-on experience of neurosurgeons and a comprehensive description of radiosurgery. (Distributed by Thieme for the American Association of Neurological Surgeons)
This publication provides an excellent overview of Japan's 20-year experience with stereotactic radiosurgery using the Leksell Gamma Knife. Leading experts discuss their long-term results with gamma knife radiosurgery. Studies focusing on dose selection for optimal treatment results and avoidance of complications are also presented. In addition, gamma knife treatments of extracranial pathologies are reviewed.
Principles and Practice of Stereotactic Radiosurgery, Second Edition serves as the definitive reference textbook for SRS practitioners. It provides a theoretical basis for the use of therapeutic radiation including imaging techniques and radiobiology. The bulk of the textbook contains chapters that are comprehensive in scope on all diseases that are treated by SRS. Lastly, it addresses administrative and technical aspects of running an SRS unit. Each chapter provides an expansive treatment of the subject, with emphasis placed on the technical aspects of SRS so that practitioners in this field can use it as a daily reference. Written by noted experts in the field, Principles and Practice of Stereotactic Radiosurgery, Second Edition is the only reference needed for neurosurgeons, radiation oncologists and medical physicists at all levels of training and practice who are interested in SRS.
An excellent summary of more than 30 years of accumulated experience Clinical outcomes of brain vascular malformation have been greatly improved by advances in microsurgery, endovascular techniques and stereotactic radiosurgery. Radiosurgery has proven to be the least invasive technique and is associated with documented long-term success. The papers in this volume present the experience of leading brain vascular malformation specialists who describe the outcome of radiosurgery for arteriovenous malformations, cavernous malformations and dural arteriovenous fistulas. These reviews expand the knowledge of the role of stereotactic radiosurgery alone or in combination with other treatment modalities. Evidence-based guidelines are included in each section to provide a summary of the current management strategies. This unique publication includes additional data that will further define the long-term benefit and risks of radiosurgery for these often complex vascular disorders and makes valuable reading for neurosurgeons, neurologists and endovascular specialists interested in an excellent summary of more than 30 years of accumulated experience in the management of brain vascular malformations.
This open access book presents the diagnosis, investigation and treatment of neurovascular diseases, and offers expert opinions and advice on avoiding complications in neurovascular surgery. It also covers complication management and post-operative follow-up care. The book is divided in to three parts; the first part discusses common approaches in neurovascular surgery, describing the steps, indications for and limitations of the approach, as well as the associated complications and how to avoid them. The second part addresses surgical treatment based on pathology, taking the different locations of lesions into consideration. The third part focuses on the technological developments that support neurovascular surgery, which may not be available everywhere, but have been included to help vascular surgeon understand the principles. This book is a guide for young neurosurgeons, neurosurgery residents and neurosurgery fellows, as well as for medical students and nurses who are interested in neurosurgery or are associated with this field in any way. It is also a useful teaching aid for senior neurosurgeons.