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Biotechnology has the potential to improve people’s quality of life and holds the key to many unmet clinical needs. In the UK alone the biotechnology market is worth £4.5 billion and estimates of future growth range from 10 to 15%. This growth can only be driven by the increased use of inexpensive and easy to manufacture polymeric biomaterials. Although polymer science is a rapidly developing area of research, it remains that one of the most intractable problems encountered in biotechnology is that the performance of polymeric biomaterials depend upon both the bulk and surface properties. In this book the authors describe their work using lasers to modify the wettability characteristics of nylon 6,6 (as wetting is often the primary factor dictating the adhesion and bonding potential of materials) as a route to enhancing the surface in terms of in vitro osteoblast cell response. What is more, modifying wettability characteristics in this way is shown to be a highly attractive means of estimating the biofunctionality of a polymer. The book demonstrates and explains how the generation of a biomimetic surface on polymers using laser beams provides an in vitro platform on which to deposit and grow cells for either the development of implants or to reconstitute functional tissue. The correlative trends and generic characteristics which are identified in the book between the laser surface treatment, wettability characteristics and osteoblast cell response of the nylon 6,6 provide a means to estimate the osteoblast cell response in vivo. The book shows clearly that laser surface modification of polymeric materials has tremendous potential for application within the field of regenerative medicine.
Laser Surface Modification of Biomaterials: Techniques and Applications covers this expanding field, which has many potential applications, including biomaterials. Laser surface modification of biomaterials enables the production of hybrid materials with different functionality in the bulk as well as the thin, sub-micrometer surface layer. This book will provide readers with a comprehensive review of the technology and its applications. Chapters in Part 1 look at the techniques and considerations of laser surface modification, while Part 2 reviews laser surface modification techniques of the most important classes of biomaterials, with a final set of chapters discussing application specific laser surface modification. - Offers a comprehensive review of laser surface modification techniques - Presents recent developments, fundamentals, and progress in laser surface modification - Reviews laser surface modification applications across a range of materials - Emphasizes applications in biomaterials
Corrosion and erosion processes often occur synergistically to cause serious damage to metal alloys. Laser surface modification techniques such as laser surface melting or alloying are being increasingly used to treat surfaces to prevent corrosion or repair corroded or damaged components. Laser surface modification of alloys for corrosion and erosion resistance reviews the wealth of recent research on these important techniques and their applications.After an introductory overview, part one reviews the use of laser surface melting and other techniques to improve the corrosion resistance of stainless and other steels as well as nickel-titanium and a range of other alloys. Part two covers the use of laser surface modification to prevent different types of erosion, including liquid impingement, slurry (solid particle) and electrical erosion as well as laser remanufacturing of damaged components.With its distinguished editor and international team of contributors, Laser surface modification of alloys for corrosion and erosion resistance is a standard reference for all those concerned with preventing corrosion and erosion damage in metallic components in sectors as diverse as energy production and electrical engineering. - Reviews recent research on the use of laser surface modification techniques, including the prevention of corrosion and repair of corroded or damaged components - Discusses the techniques for improving the corrosion resistance of steels, nickel-titanium and a range of alloys - Analyses the use of laser surface modification to prevent different types of erosion, including liquid impingement and laser remanufacturing of damaged components
The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials' community. - The most comprehensive coverage of principles and applications of all classes of biomaterials - Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. - Online chapter exercises available for most chapters
Biomaterials work in contact with living matter and this gives a number of specific requirements for their surface properties, such as bioinertness or bioactivity, antibiofouling, and so on. Surface engineering based on physical, chemical, physical-chemical, biochemical or biological principles is important for the preparation of biomaterials with the desired biocontact properties. This book helps the reader gain the knowledge to enable them to work in such a rapidly developing area, with a comprehensive list of references given for each chapter. Strategies for tailoring the biological response through the creation of biomaterial surfaces resistant to fouling are discussed. Methods of eliciting specific biomolecular interactions that can be further combined with patterning techniques to engineer adhesive areas in a noninteractive background are also covered. The theoretical basis of surface engineering for improvement of biocontact properties of polymeric biomaterials as well as the current state-of-the-art of the surface engineering of polymeric biomaterials are presented. The book also includes information on the most used conventional and advanced surface engineering methods. The book is targeted at researchers, post-doctorates, graduate students, and those already working in the field of biomaterials with a special interest in the creation of polymeric materials with improved biocontact properties via surface engineering.
This second edition of Biomaterials Science leads the field by providing a balanced, insightful view of biomaterials. Contributions from pre-eminent researchers and practitioners from diverse academic and professional backgrounds have been integrated into a cohesive curriculum which includes pertinent principles of cell biology, immunology and pathology focusing on the clinical uses of biomaterials as components of implants, devices, and artificial organs, and their uses in biotechnology. The materials science and engineering of synthetic and natural biomaterials and the characterization of their physical, chemical, biochemical and surface properties, and mechanisms and evaluation of interactions with tissue, are also addressed in detail. Book jacket.
The book provides a unique overview on laser techniques and applications for the purpose of improving adhesion by altering surface chemistry and topography/morphology of the substrate. It details laser surface modification techniques for a wide range of industrially relevant materials (plastics, metals, ceramics, composites) with the aim to improve and enhance their adhesion to other materials. The joining of different materials is of critical importance in the fabrication of many and varied products.
POLYMER SURFACE MODIFICATION TO ENHANCE ADHESION This unique, comprehensive and groundbreaking book is the first on this important subject. Polymer Surface Modification to Enhance Adhesion comprises 13 chapters and is divided into two parts: Part 1: Energetic Treatments; and Part 2: Chemical Treatments. Topics covered include atmospheric pressure plasma treatment of polymers to enhance adhesion; corona treatment of polymer surfaces to enhance adhesion; flame surface treatment of polymers to enhance adhesion; vacuum UV photo-oxidation of polymer surfaces to enhance adhesion; optimization of adhesion of polymers using photochemical surface modification UV/Ozone surface treatment of polymers to enhance adhesion; adhesion enhancement of polymer surfaces by ion beam treatment; polymer surface modification by charged particles; laser surface modification of polymeric materials; competition in adhesion between polysort and monosort functionalized polyolefinic surfaces; amine-terminated dendritic materials for polymer surface modification; arginine-glycine-aspartic acid (RGD) modification of polymer surfaces; and adhesion promoters for polymer surfaces. Audience The book will be of great interest to polymer scientists, surface scientists, adhesionists, materials scientists, plastics engineers, and to those involved in adhesive bonding, packaging, printing, painting, metallization, biological adhesion, biomedical devices, and polymer composites.
With the ever-increasing amount of research being published it is a Herculean task to be fully conversant with the latest research developments in any field, and the arena of adhesion and adhesives is no exception. Thus, topical review articles provide an alternate and very efficient way to stay abreast of the state-of-the-art in may subjects representing the field of adhesion science and adheisves. Based on the success and the warm reception accorded to the premier volume in this series “Progress in Adhesion and Adhesives” (containing the review articles published in Volume 2 (2014) of the journal Reviews of Adhesion and Adhesives (RAA)), volume 2 comprises 14 review articles published in Volume 4 (2016) of RAA. The subjects of these 14 reviews fall into the following general areas: 1. Surface modification of polymers for a variety of purposes. 2. Adhesion aspects in reinforced composites 3. Thin films/coatings and their adhesion measurement 4. Bioadhesion and bio-implants 5. Adhesives and adhesive joints 6. General adhesion aspects The topics covered include: surface modification of natural fibers for reinforced polymer composites; adhesion of submicrometer thin metals films; surface treatments to modulate bioadhesion; hot-melt adhesives from renewable resources; particulate-polymer composites; functionally graded adhesively bonded joints; fabrication of nano-biodevices; effects of particulates on contact angles , thermal stresses in adhesively bonded joints and ways to mitigate these; laser-assisted electroless metallization of polymer materials; adhesion measurement of coatings on biodevices/implants; cyanoacrylate adhesives; and adhesion of green flame retardant coatings onto polyolefins.
Development of the thin film and coating technologies (TFCT) made possible the technological revolution in electronics and through it the revolution in IT and communications in the end of the twentieth century. Now, TFCT penetrated in many sectors of human life and industry: biology and medicine; nuclear, fusion, and hydrogen energy; protection against corrosion and hydrogen embrittlement; jet engine; space materials science; and many others. Currently, TFCT along with nanotechnologies is the most promising for the development of almost all industries. The 20 chapters of this book present the achievements of thin-film technology in many areas mentioned above but more than any other in medicine and biology and energy saving and energy efficiency.