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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
From the acclaimed author of "The Dark Bride" comes a new novella published in a bilingual English/Spanish edition.
ñI tell you, God could care less about the poor. Tell me, why must we live here like this? What have we done to deserve this? YouÍre so good and yet you suffer so much,î a young boy tells his mother in Tomàs RiveraÍs classic novel about the migrant worker experience. Outside the chicken coop that is their home, his father wails in pain from the unbearable cramps brought on by sunstroke after working in the hot fields. The young boy canÍt understand his parentsÍ faith in a god that would impose such horrible suffering, poverty and injustice on innocent people. Adapted into the award-winning film ƒand the earth did not swallow him and recipient of the first award for Chicano literature, the Premio Quinto Sol, in 1970, RiveraÍs masterpiece recounts the experiences of a Mexican-American community through the eyes of a young boy. Forced to leave their home in search of work, the migrants are exploited by farmers, shopkeepers, even other Mexican Americans, and the boy must forge his identity in the face of exploitation, death and disease, constant moving and conflicts with school officials. In this new edition of a powerful novel comprised of short vignettes, Rivera writes hauntingly about alienation, love and betrayal, man and nature, death and resurrection and the search for community.
An edited group of 21 papers on urban change; in addition, the author contributed the four initial chapters on theoretical methods. The remaining papers consider factors of urban change, mostly for the latter part of the 20th century, for countries in Europe, the Americas, South Africa, and Asia. Themes include migration, population change, and the impact of political change. The international group of contributors is made up of academics in geography, urban and regional planning, and demography.
Millions of children are on the move, both within and between countries, with or without their parents. The conditions under which movement takes place are often treacherous, putting migrant children, especially unaccompanied and separated children, at an increased risk of economic or sexual exploitation, abuse, neglect and violence. Policy responses to protect and support these migrant children are often fragmented and inconsistent and while children on the move have become a recognised part of today's global and mixed migration flows they are still largely invisible in debates on both child protection and migration.
The second volume in IOM's series on migrant deaths, Fatal Journeys has two main objectives. First, it provides an update of global trends in migrant fatalities since 2014. Data on the number and profile of dead and missing migrants are presented for different regions of the world, drawing upon the data collected through IOM's Missing Migrants Project. Second, the report examines the challenges facing families and authorities seeking to identify and trace missing migrants. The study compares practices in different parts of the world, and identifies a number of innovative measures that could potentially be replicated elsewhere.
Presents a people-centred approach to development.