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The “essential” companion to the landmark Users' Guides to the Medical Literature - completely revised and updated! 5 STAR DOODY'S REVIEW! "This second edition is even better than the original. Information is easier to find and the additional resources that will be available at www.JAMAevidence.com will provide readers with a one-stop source for evidence-based medicine."--Doody's Review Service Evidence-based medicine involves the careful interpretation of medical studies and its clinical application. And no resource helps you do it better-and faster-than Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice. This streamlined reference distills the most clinically-relevant coverage from the parent Users' Guide Manual into one highly-focused, portable resource. Praised for its clear explanations of detailed statistical and mathematical principles, The Essentials concisely covers all the basic concepts of evidence-based medicine--everything you need to deliver optimal patient care. It's a perfect at-a-glance source for busy clinicians and students, helping you distinguish between solid medical evidence and poor medical evidence, tailor evidence-based medicine for each patient, and much more. Now in its second edition, this carry-along quick reference is more clinically relevant--and more essential--than ever! FEATURES Completely revised and updated with all new coverage of the basic issues in evidence-based medicine in patient care Abundant real-world examples drawn from the medical literature are woven throughout, and include important related principles and pitfalls in using clinical research in patient care decisions Edited by over 60 internationally recognized editors and contributors from around the globe Also look for JAMAevidence.com, a new interactive database for the best practice of evidence based medicine.
Suelette Dreyfus and her co-author, WikiLeaks founder Julian Assange, tell the extraordinary true story of the computer underground, and the bizarre lives and crimes of an elite ring of international hackers who took on the establishment. Spanning three continents and a decade of high level infiltration, they created chaos amongst some of the world's biggest and most powerful organisations, including NASA and the US military. Brilliant and obsessed, many of them found themselves addicted to hacking and phreaking. Some descended into drugs and madness, others ended up in jail. As riveting as the finest detective novel and meticulously researched, Underground follows the hackers through their crimes, their betrayals, the hunt, raids and investigations. It is a gripping tale of the digital underground.
When plucky Kit Feeny moves to a new town, he immediately makes an enemy of the sadistic school bully and must struggle to find friends who share his interests.
It: Chapter Two—now a major motion picture! Stephen King’s terrifying, classic #1 New York Times bestseller, “a landmark in American literature” (Chicago Sun-Times)—about seven adults who return to their hometown to confront a nightmare they had first stumbled on as teenagers…an evil without a name: It. Welcome to Derry, Maine. It’s a small city, a place as hauntingly familiar as your own hometown. Only in Derry the haunting is real. They were seven teenagers when they first stumbled upon the horror. Now they are grown-up men and women who have gone out into the big world to gain success and happiness. But the promise they made twenty-eight years ago calls them reunite in the same place where, as teenagers, they battled an evil creature that preyed on the city’s children. Now, children are being murdered again and their repressed memories of that terrifying summer return as they prepare to once again battle the monster lurking in Derry’s sewers. Readers of Stephen King know that Derry, Maine, is a place with a deep, dark hold on the author. It reappears in many of his books, including Bag of Bones, Hearts in Atlantis, and 11/22/63. But it all starts with It. “Stephen King’s most mature work” (St. Petersburg Times), “It will overwhelm you…to be read in a well-lit room only” (Los Angeles Times).
Modern perfumery is a blend of art, science and technology, with chemistry being the central science involved. The Chemistry of Fragrances aims to educate and entertain, and inform the audience of the very latest chemistry, techniques and tools applied to fragrance creativity. Beginning with the history of perfumes, which goes back over fifty thousand years, the book goes on to discuss the structure of the Perfume Industry today. The focus then turns to an imaginary brief to create a perfume, and the response to it, including that of the chemist and the creative perfumer. Consumer research, toxicological concerns, and the use of the electronic nose are some of the topics discussed on this journey of discovery. Written by respected experts in their fields, this unique book gives an insider view of ""mixing molecules"" from behind the portals of modern-day alchemy. It will be enjoyed by chemists and marketeers at all levels.
Preface. 1. Introduction. 2. Production of terpenes and terpenoids. 3. The origin and evolution of terpenoid messengers. 4. Specific properties of terpenoids. 5. Functions of natural terpenoids in the interrelationships between organisms. 6. Terpenoids in practice. 7. Natural terpenoids to the benefit of human health. 8. Prospectus and suggestions for further research. Epilogue. References. General reading. Glossary. Index.
This manual will enable the user to identify the changes that need to be made in order to leverage the company's intellectual capital and to bring about the processes, infractructure and organizational procedures that will enable you to build and use your corporate knowledge base.