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The topics covered by this volume include: protein destabilization at low temperatures; engineering the stability and function of Gene V Protein; free energy balance in protein folding; modelling protein stability as a heteropolymer collapse; stability of alpha helices; protein stability with T4 Lysozyme.
This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics.
Kinetic Control in Synthesis and Self-Assembly provides a unique overview of the fundamental principles, novel methods and practical applications for researchers across organic synthesis, supramolecular chemistry and materials sciences. The book examines naturally occurring molecular systems in which kinetic processes are more ubiquitous than thermodynamic processes, also exploring the control of reactions and molecular self-assemblies, through kinetic processes, in artificial systems. These methods currently play a crucial role for tuning materials functions. From organic synthesis, to supramolecular assemblies, and from restricted spaces, to material synthesis for hierarchical structures, the book offers valuable coverage for researchers across disciplines. Interesting topics include how to regulate kinetic pathways more precisely, essential molecular design for kinetic traps, and how molecular environments surrounding molecules (i.e., solvent, temperature, and pressure effects) influence kinetic control in reactions and self-assemblies.
Understanding time-dependent behaviors of nuclear reactors and the methods of their control is essential to the operation and safety of nuclear power plants. This book provides graduate students, researchers, and engineers in nuclear engineering comprehensive information on both the fundamental theory of nuclear reactor kinetics and control and the state-of-the-art practice in actual plants, as well as the idea of how to bridge the two. The first part focuses on understanding fundamental nuclear kinetics. It introduces delayed neutrons, fission chain reactions, point kinetics theory, reactivity feedbacks, and related measurement techniques. The second part helps readers to grasp the theories and practice of nuclear power plant control. It introduces control theory, nuclear reactor stability, and the operation and control of existing nuclear power plants such as a typical pressurized water reactor, a typical boiling water reactor, the prototype fast breeder reactor Monju, and the high-temperature gas-cooled test reactor (HTTR). Wherever possible, the design and operation data for these plants are provided.
This edition of this this flight stability and controls guide features an unintimidating math level, full coverage of terminology, and expanded discussions of classical to modern control theory and autopilot designs. Extensive examples, problems, and historical notes, make this concise book a vital addition to the engineer's library.
The expertise of a professional mathmatician and a theoretical engineer provides a fresh perspective of stability and stable oscillations. The current state of affairs in stability theory, absolute stability of control systems, and stable oscillations of both periodic and almost periodic discrete systems is presented, including many applications in engineering such as stability of digital filters, digitally controlled thermal processes, neurodynamics, and chemical kinetics. This book will be an invaluable reference source for those whose work is in the area of discrete dynamical systems, difference equations, and control theory or applied areas that use discrete time models.
This text is designed as a clinical reference to develop knowledge of the examination, diagnosis and classification of uncontrolled movement (motor control dysfunction) and the management of movement dysfunction. It will help the therapist: Develop clinical skills in the assessment and retraining of movement control To use movement control tests to identify uncontrolled movement To classify uncontrolled movement into diagnostic subgroups Access a large range of motor control and movement retraining strategies Develop an assessment framework that will provide a diagnosis of dysfunction, pain sensitive tissues and pain mechanisms Use a clinical reasoning framework to prioritise clinical decision making