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In the area of bioinorganic chemistry, transition metal complexes of Schiff bases have attracted a lot of interest due to their potent biological activities such as: Anti-bacterial active. Anti-fungal active. Anti-cancer active. Antioxidant active. Antimalarial active. Antiviral active. Anti-in ammatory active. It was reported that complexation of metals to Schiff base ligands improves the antimicrobial and anticancer activities of the ligands. Some research groups found that the Schiff base metal complexes derived from salicylaldehyde can specially cleave the DNA. Also, Schiff bases used in the following: As gravimetric reagent. For removal of uranium (VI) from aqueous solutions. As urease inhibitor. As corrosion inhibitor. Iron Schiff base complexes provide useful structural and electronic models for the similarly coordinated sites found in the heme iron enzymes and their structure and catalytic activity are analogous with those of iron porphyrins. Studying the interaction between transition metal complexes and DNA has attracted many interests due to their importance in cancer therapy, design of new types of pharmaceutical molecules and molecular biology.
RNA-Ligand Interactions, Part B focuses on molecular biology methods. Major topics covered include: solution probe methods, tethered-probe methodologies, in vitro affinity selection methodologies, genetic methodologies for detecting RNA-protein interactions, protein engineering methodologies useful for RNA-protein interaction studies, and cell biology methods.RNA-Ligand Interactions, Part A, its companion, VOLUME 317 focuses on structural biology methods.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
The Proceedings of the National Academy of Sciences (PNAS) publishes research reports, commentaries, reviews, colloquium papers, and actions of the Academy. PNAS is a multidisciplinary journal that covers the biological, physical, and social sciences.
A classified world list of new papers in pure chemistry.