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The chemical properties of superoxide ion, its biological role, and the role of other oxygen radicals which arise as a result of its transformations are contained in this text. In Volume I the principal reactions of superoxide ion, including protonation reactions with proton donors, nucleophilic reactions with esters, alkyl halides and other compounds, electron transfer reactions with quinones and metal complexes, are described. Basic quantitative data including rate constants and yields for the reactions of superoxide ion of all types are given in tables. This volumecontains the mechanisms of the generation of oxygen radicals in cells and the interaction of superoxide ion with cell components. The role of superoxide ion in lipid peroxidation and destruction of proteins and nucleic acids is explained, as well as oxygen radicals in the mechanisms of toxic and therapeutic action of drugs, especially anticancer antibiotics. In addition, the action of superoxide ion and other oxygen radicals on plants, micro-, and macroorganisms is discussed, along with the role of oxygen radicals in normal metabolic and pathological processes.
Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.
This bibliography on the geographical, water and geological information ofSomalia was begun to fill a request for current information on that war tornstate. This bibliography brings together selected citations from a variety ofdifferent cartographic, geographical, geological and hydrological resourcesand a number of specialized library collections. Most of the citations havelocation information on where these items can be located and either used onsite, or borrowed through inter-library loan, or where copies of the itemscan be purchased from the originating source, or through commercial documentdelivery services.
Honorable Mention, 2010 Best First Book, Association for Spanish and Portuguese Historical Studies In 1492, Granada, the last independent Muslim city on the Iberian Peninsula, fell to the Catholic forces of Ferdinand and Isabella. A century later, in 1595, treasure hunters unearthed some curious lead tablets inscribed in Arabic. The tablets documented the evangelization of Granada in the first century A.D. by St. Cecilio, the city’s first bishop. Granadinos greeted these curious documents, known as the plomos, and the human remains accompanying them as proof that their city—best known as the last outpost of Spanish Islam—was in truth Iberia’s most ancient Christian settlement. Critics, however, pointed to the documents’ questionable doctrinal content and historical anachronisms. In 1682, the pope condemned the plomos as forgeries. From Muslim to Christian Granada explores how the people of Granada created a new civic identity around these famous forgeries. Through an analysis of the sermons, ceremonies, histories, maps, and devotions that developed around the plomos, it examines the symbolic and mythological aspects of a new historical terrain upon which Granadinos located themselves and their city. Discussing the ways in which one local community’s collective identity was constructed and maintained, this work complements ongoing scholarship concerning the development of communal identities in modern Europe. Through its focus on the intersections of local religion and local identity, it offers new perspectives on the impact and implementation of Counter-Reformation Catholicism.
Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an
With contributions by numerous experts
Tomorrow's best physicians will be those who continually learn, adjust, and innovate as new information and best practices evolve, reflecting adaptive expertise in response to practice challenges. As the first volume in the American Medical Association's MedEd Innovation Series, The Master Adaptive Learner is an instructor-focused guide covering models for how to train and teach future clinicians who need to develop these adaptive skills and utilize them throughout their careers. - Explains and clarifies the concept of a Master Adaptive Learner: a metacognitive approach to learning based on self-regulation that fosters the success and use of adaptive expertise in practice. - Contains both theoretical and practical material for instructors and administrators, including guidance on how to implement a Master Adaptive Learner approach in today's institutions. - Gives instructors the tools needed to empower students to become efficient and successful adaptive learners. - Helps medical faculty and instructors address gaps in physician training and prepare new doctors to practice effectively in 21st century healthcare systems. - One of the American Medical Association Change MedEd initiatives and innovations, written and edited by members of the ACE (Accelerating Change in Medical Education) Consortium – a unique, innovative collaborative that allows for the sharing and dissemination of groundbreaking ideas and projects.
Provides guidelines for managing this grossly underdiagnosed and undertreated condition, focusing on early detection and timely, effective interventions.