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Nuclear Oncology a contemporary narrative of the role of nuclear medicine in oncology with an emphasis on SPECT/CT and PET/CT with additional comments when appropriate on the potential application of PET/MR and to a lesser degree, targeted radionuclide therapy. This book focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases. It describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology. The basic science and current research topics of nuclear oncology are addressed in separate chapters. Nuclear medicine has become an essential component to all phases of the management of the patient with a malignant tumor and in some cases, even benign neoplasms. The standard of practice for many tumors requires PET/CT imaging at various stages of diagnosis and management. In addition to clinical applications, ongoing investigational efforts, which more and more involve multi-institutional protocols, are also presented. Features: • Focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases • Emphasizes SPECT/CT and PET/CT with additional emphasis on the potential application of PET/MR • Describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology
This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.
This concise Question & Answer book contains three types of questions: multiple choice, fill-in answers, & true & false. The quick test format is a concise, yet comprehensive rapid review primarily designed for those preparing for certification or re-certification exams administered by the American Board of Radiology & the American Board of Nuclear Medicine. It is organized into 12 major categories, containing more than 1,000 questions & answers.
Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
"Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.
There is general recognition that nuclear cardiology, and particularly myocardial perfusion scintigraphy (MPS), is under-utilized in the UK when compared with practice in mainland Europe and the USA. The National Institute for Clinical Excellence (NICE) is about to issue a report that will recognize the shortfall in provision, and this should lead
The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.