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The Integrated Risk Information System (IRIS) is the EPA's most comprehensive database for hazardous environmental chemicals. Updated quarterly, it covers five major subject categories: Chronic health hazard assessment for noncarcinogenic effects Carcinogenicity assessment for lifetime exposure Health hazard assessments for varied exposure durations U.S. EPA regulatory actions Supplementary data, references, and synonyms IRIS (Integrated Risk Information System) Features: Our version of the IRIS database is available at a significant savings over the government's version and features powerful searching capabilities, printing and exporting features, and automatic installation... Data for this package is compiled into a series of alphabetized searchable files that comes complete with a menu-driven search program to make finding information quick and painless. The database also features an automatic installation program and can generate reports as printed copies or electronic files ready for import into a word processor. Load as much or as little of the information you need from the database for fast results on your personal computer. When your IRIS quarterly updates arrive, simply load the new disks on your computer and the latest version of the complete IRIS database is at your fingertips. Even better, our version of the IRIS database is available at a significant savings over the government's version, and features powerful searching capabilities, printing and exporting features, and automatic installation. The most comprehensive data available for hazardous substances... IRIS (Integrated Risk Information System) features comprehensive information for about 500 hazardous regulated and unregulated substances. This number increases every three months with the addition of new files and revisions to existing information. Unlike other databases that provide summaries or abbreviated data, IRIS gives you extensive textual and numeric information complete with EPA contacts and full references. IRIS is the database to use to obtain the critical toxicity, regulatory, risk assessment, medical, chemical and physical property data you'll need for risk evaluations, regulatory decisions, and other uses. And with its quarterly updates, your information never grows old. Chronic health hazard assessments include reference doses for chronic oral exposure and inhalation exposure. Carcinogenicity assessment data includes evidence for classification as to human carcinogenicity; quantitative estimates of carcinogenic risk from oral exposure and inhalation exposure; and EPA documentation, review, and contacts. Health hazards assessments provide information from EPA's Drinking Water Health Advisories (including health advisories for children and adults, organoleptic properties, taste and odor, analytical methods for detection in drinking water, water treatment, documentation and EPA contacts). What Does IRIS Provide? Complete U.S. EPA regulatory action data is presented for: Clean Air Act (including NAAQS, NESHAP, and NSPS) Safe Drinking Water Act (including MCLGs, MCLs, and SMCLs) Clean Water Act Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) Toxic Substances Control Act (TSCA) Resource Conservation and Recovery Act (RCRA) (including Appendix 9) Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) (including Superfund data) Reportable quantity data for the release of substances into the environment IRIS's supplementary data includes important information such as: Acute health hazard information (e.g., toxicity, medical conditions) Physical and chemical properties (e.g., formula, vapor pressure, flash point) References and synonyms IRIS Chemical Information Database is one of the most important reference sources available for toxicologists, chemists, chemical engineers, ecologists, environmental scientists, regulators, industrial hygienists, occupational physicians, government administrators, emergency response personnel, hazardous material response teams, lawyers, union representatives, insurance companies, commercial realtors and lending institutions, property pre-acquisition auditors, analytical laboratories, and libraries. System Requirements: To use the IRIS Chemical Information Database, you need IBM® or IBM-compatible equipment with 640K RAM and a hard drive with 2 to 15MB of available disk space (depending on the number of disks you load). DOS 2.0 or higher is also required. Diskettes can be ordered in either 5.25" or 3.5" formats. The IRIS Chemical Information Database is an annual subscription product updated on a quarterly basis. A user's manual is included in the subscription price. Each update will be automatically sent to you unless you cancel your subscription. Because each update replaces the previous version of the IRIS database, you can be sure that you will receive the most current version, including searching, printing, and installation capabilities, regardless of what time of year you initially subscribe. Subscription renewal information for 1993 will automatically be sent to current subscribers.
The US Environmental Protection Agency (EPA) Integrated Risk Information System (IRIS) program develops toxicologic assessments of environmental contaminants. IRIS assessments provide hazard identification and dose-response assessment information. The information is then used in conjunction with exposure information to characterize risks to public health and may be used in risk-based decisionmaking, in regulatory actions, and for other risk-management purposes. Since the middle 1990s, EPA has been in the process of updating the IRIS assessment of inorganic arsenic. In response to a congressional mandate for an independent review of the IRIS assessment of inorganic arsenic, EPA requested that the National Research Council convene a committee to conduct a two-phase study. Critical Aspects of EPA's IRIS Assessment of Inorganic Arsenic is the report of the first phase of that study. This report evaluates critical scientific issues in assessing cancer and noncancer effects of oral exposure to inorganic arsenic and offers recommendations on how the issues could be addressed in EPA's IRIS assessment.
Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.
This volume describes the methods used in the surveillance of drinking water quality in the light of the special problems of small-community supplies, particularly in developing countries, and outlines the strategies necessary to ensure that surveillance is effective.
On cover: IPCS International Programme on Chemical Safety. Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization and the World Health Organization, and produced within the framework of the Inter-organization Programme for the Sound Management of Chemicals (IOMC)
The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. - The only book available dealing with the practical aspects of medicinal chemistry - Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production - Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry