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Introductory Mathematics for the Life Sciences offers a straightforward introduction to the mathematical principles needed for studies in the life sciences. Starting with the basics of numbers, fractions, ratios, and percentages, the author explains progressively more sophisticated concepts, from algebra, measurement, and scientific notation through the linear, power, exponential, and logarithmic functions to introductory statistics. Worked examples illustrate concepts, applications, and interpretations, and exercises at the end of each chapter help readers apply and practice the skills they develop. Answers to the exercises are posted at the end of the text.
A few decades ago mathematics played a modest role in life sciences. Today, however, a great variety of mathematical methods is applied in biology and medicine. Practically every mathematical procedure that is useful in physics, chemistry, engineering, and economics has also found an important application in the life sciences. The past and present training of life scientists does by no means reflect this development. However, the impact ofthe fast growing number of applications of mathematical methods makes it indispensable that students in the life sciences are offered a basic training in mathematics, both on the undergraduate and the graduate level. This book is primarily designed as a textbook for an introductory course. Life scientists may also use it as a reference to find mathematical methods suitable to their research problems. Moreover, the book should be appropriate for self-teaching. It will also be a guide for teachers. Numerous references are included to assist the reader in his search for the pertinent literature.
An accessible undergraduate textbook on the essential math concepts used in the life sciences The life sciences deal with a vast array of problems at different spatial, temporal, and organizational scales. The mathematics necessary to describe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that are rarely taught in standard undergraduate courses. This textbook provides an accessible introduction to these critical mathematical concepts, linking them to biological observation and theory while also presenting the computational tools needed to address problems not readily investigated using mathematics alone. Proven in the classroom and requiring only a background in high school math, Mathematics for the Life Sciences doesn't just focus on calculus as do most other textbooks on the subject. It covers deterministic methods and those that incorporate uncertainty, problems in discrete and continuous time, probability, graphing and data analysis, matrix modeling, difference equations, differential equations, and much more. The book uses MATLAB throughout, explaining how to use it, write code, and connect models to data in examples chosen from across the life sciences. Provides undergraduate life science students with a succinct overview of major mathematical concepts that are essential for modern biology Covers all the major quantitative concepts that national reports have identified as the ideal components of an entry-level course for life science students Provides good background for the MCAT, which now includes data-based and statistical reasoning Explicitly links data and math modeling Includes end-of-chapter homework problems, end-of-unit student projects, and select answers to homework problems Uses MATLAB throughout, and MATLAB m-files with an R supplement are available online Prepares students to read with comprehension the growing quantitative literature across the life sciences A solutions manual for professors and an illustration package is available
This book is intended to be an introduction to Delay Differential Equations for upper level undergraduates or beginning graduate mathematics students who have a reasonable background in ordinary differential equations and who would like to get to the applications quickly. The author has used preliminary notes in teaching such a course at Arizona State University over the past two years. This book focuses on the key tools necessary to understand the applications literature involving delay equations and to construct and analyze mathematical models involving delay differential equations. The book begins with a survey of mathematical models involving delay equations.
Provides a wide range of mathematical models currently used in the life sciences Each model is thoroughly explained and illustrated by example Includes three appendices to allow for independent reading
The aim of this book is to introduce the subject of mathematical modeling in the life sciences. It is intended for students of mathematics, the physical sciences, and engineering who are curious about biology. Additionally, it will be useful to students of the life sciences and medicine who are unsatisfied with mere description and who seek an understanding of biological mechanism and dynamics through the use of mathematics. The book will be particularly useful to premedical students, because it will introduce them not only to a collection of mathematical methods but also to an assortment of phenomena involving genetics, epidemics, and the physiology of the heart, lung, and kidney. Because of its introductory character, mathematical prerequisites are kept to a minimum; they involve only what is usually covered in the first semester of a calculus sequence. The authors have drawn on their extensive experience as modelers to select examples which are simple enough to be understood at this elementary level and yet realistic enough to capture the essence of significant biological phenomena drawn from the areas of population dynamics and physiology. Because the models presented are realistic, the book can serve not only as an introduction to mathematical methods but also as a mathematical introduction to the biological material itself. For the student, who enjoys mathematics, such an introduction will be far more stimulating and satisfying than the purely descriptive approach that is traditional in the biological sciences.
Biology is a source of fascination for most scientists, whether their training is in the life sciences or not. In particular, there is a special satisfaction in discovering an understanding of biology in the context of another science like mathematics. Fortunately there are plenty of interesting (and fun) problems in biology, and virtually all scientific disciplines have become the richer for it. For example, two major journals, Mathematical Biosciences and Journal of Mathematical Biology, have tripled in size since their inceptions 20-25 years ago. The various sciences have a great deal to give to one another, but there are still too many fences separating them. In writing this book we have adopted the philosophy that mathematical biology is not merely the intrusion of one science into another, but has a unity of its own, in which both the biology and the math ematics should be equal and complete, and should flow smoothly into and out of one another. We have taught mathematical biology with this philosophy in mind and have seen profound changes in the outlooks of our science and engineering students: The attitude of "Oh no, another pendulum on a spring problem!," or "Yet one more LCD circuit!" completely disappeared in the face of applications of mathematics in biology. There is a timeliness in calculating a protocol for ad ministering a drug.
The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. It provides a fascinating survey of the theory of dynamical systems in biology and medicine. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.
The result of lectures given by the authors at New York University, the University of Utah, and Michigan State University, the material is written for students who have had only one term of calculus, but it contains material that can be used in modeling courses in applied mathematics at all levels through early graduate courses. Numerous exercises are given as well as solutions to selected exercises, so as to lead readers to discover interesting extensions of that material. Throughout, illustrations depict physiological processes, population biology phenomena, corresponding models, and the results of computer simulations. Topics covered range from population phenomena to demographics, genetics, epidemics and dispersal; in physiological processes, including the circulation, gas exchange in the lungs, control of cell volume, the renal counter-current multiplier mechanism, and muscle mechanics; to mechanisms of neural control. Each chapter is graded in difficulty, so a reading of the first parts of each provides an elementary introduction to the processes and their models.
​ ​​ Mathematics for the Life Sciences provides present and future biologists with the mathematical concepts and tools needed to understand and use mathematical models and read advanced mathematical biology books. It presents mathematics in biological contexts, focusing on the central mathematical ideas, and providing detailed explanations. The author assumes no mathematics background beyond algebra and precalculus. Calculus is presented as a one-chapter primer that is suitable for readers who have not studied the subject before, as well as readers who have taken a calculus course and need a review. This primer is followed by a novel chapter on mathematical modeling that begins with discussions of biological data and the basic principles of modeling. The remainder of the chapter introduces the reader to topics in mechanistic modeling (deriving models from biological assumptions) and empirical modeling (using data to parameterize and select models). The modeling chapter contains a thorough treatment of key ideas and techniques that are often neglected in mathematics books. It also provides the reader with a sophisticated viewpoint and the essential background needed to make full use of the remainder of the book, which includes two chapters on probability and its applications to inferential statistics and three chapters on discrete and continuous dynamical systems. The biological content of the book is self-contained and includes many basic biology topics such as the genetic code, Mendelian genetics, population dynamics, predator-prey relationships, epidemiology, and immunology. The large number of problem sets include some drill problems along with a large number of case studies. The latter are divided into step-by-step problems and sorted into the appropriate section, allowing readers to gradually develop complete investigations from understanding the biological assumptions to a complete analysis.