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Oksana Ableitner offers a practical, clearly structured and easy to understand introduction to complicated definitions and structures in chemistry and molecular biology for work in the molecular biology laboratory. The author is guided by her experience in working with students and uses many illustrations to visualize abstract knowledge. An understanding of this matter is an essential basis for successful work with DNA and RNA in order to ensure high quality results. For responsible activities in application - such as genetic research or the determination of various pathogens - it is essential to be confident in dealing with the basics of these sensitive, fast and specific analytical methods. This Springer essential is a translation of the original German 2nd edition essentials, Einführung in die Molekularbiologie by Oksana Ableitner, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2018. The translation was done with the help of artificial intelligence (machine translation by the serviceDeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.
Basic concepts of molecular biology. Strings, graphs, and algorithms. Sequence comparasion and database search. Fragment assembly of DNA. Physical mapping of DNA. Phylogenetic trees. Genome rearrangements. Molecular structure prediction. epilogue: computing with DNA. Answers to selected exercises. References. index.
Introduction to Genetics: A Molecular Approach is a new textbook for first and second year undergraduates. It first presents molecular structures and mechanisms before introducing the more challenging concepts and terminology associated with transmission genetics.
"This book is an introductory course in molecular biology for mathematicians, physicists, and engineers. It covers the basic features of DNA, proteins, and cells but in the context of recent technological advances, such as next-generation sequencing and high-throughput screens, and their applications. This enables readers to move rapidly from the b
Introduction to Molecular Biology focuses on the principles of polymer physics and chemistry and their applications to fundamental phenomena in biological sciences. It examines the structure, synthesis, and function of nucleic acids and proteins, as well as the physicochemical techniques necessary in determining the macromolecular structure, the kinetics and mechanism of enzyme action, the genetics of bacteria and their viruses, and the genetic code. It also considers the importance of precise quantitative analysis in biochemistry and biophysics, the architecture and function of biological macromolecules, and the unique mechanisms that regulate the cell's biological activity. Organized into five chapters, this book begins with an overview of proteins and their functional activity, from contractility and enzymatic catalysis to immunological activity, formation of selectively permeable membranes, and reversible binding and transport. It explains how such functions are related to molecular interactions and therefore fall within the purview of molecular biology. The book then proceeds with a discussion on the chemical structure of proteins and nucleic acids, the physicochemical techniques in measuring molecular size and shape, the mechanism of enzymatic reactions, the functions of DNA and RNA, and the mechanism of phase transition in polynucleotides. This book is intended for both biologists and non-biologists who want to be acquainted with the advances made in molecular biology, molecular genetics, and molecular biophysics during the 1950s and 1960s.
Illustrates the Complex Biochemical Relations that Permit Life to ExistIt can be argued that the dawn of the 21st century has emerged as the age focused on molecular biology, which includes all the regulatory mechanisms that make cellular biochemical reaction pathways stable and life possible. For biomedical engineers, this concept is essential to
This introduction to molecular biology is designed for students from a science background, as the text assumes knowledge of general biology and chemistry. It emphasizes gene function and control, and applies these processes to the big picture of cell function.
Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.