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Intravitreal injections have become a common treatment method for the management of retinal diseases. The procedure is simple, performed with local anaesthetic. This book is a comprehensive guide to intravitreal injections for practising ophthalmologists. Divided into twelve chapters, it examines methods of injection and appropriate drugs for different ocular disorders. Each technique is described in detail, with discussion on complications and recommendations included. This practical guide features more than 90 images and also includes a chapter on counselling and consent forms. Key points Practical guide to intravitreal injections for ophthalmologists Covers variety of different techniques and drugs Features more than 90 images Includes chapter on counselling and consent forms
Intravitreal Injections are now standard treatment for various ocular conditions such as age-related macular degeneration, diabetic retinopathy and retinal vein occlusions. Ophthalmic nurse practitioners and allied health professionals are increasingly becoming invaluable team members for delivering these injections, particularly as the clinical demand increases.This full-colour handbook details all that a practitioner needs to know about safely performing the procedure. It will also be a useful reference for junior ophthalmic trainees.Benefits:
This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases.
Now available in a fully updated third edition, Equine Ophthalmology is the most comprehensive and current clinical resource for the diagnosis and treatment of ophthalmic disease in horses. Provides complete, authoritative information on the diagnosis and treatment of ophthalmic disease in horses Fully updated with improved figures, the latest research, and new chapters on advanced diagnostics, foal ophthalmology, neuro-ophthalmology, national and international regulations, and an expanded chapter on inherited ocular disease Features contributions from an international group of equine experts, under the editorship of a leading equine veterinary specialist Offers comprehensive coverage of clinical and reference information ideal for specialists, general equine practitioners, and veterinary students alike Includes access to a companion website with expanded content and figures
Intravitreal injections (injections into the eye) are a new form of treatment for various conditions such as age-related macular degeneration, diabetic eye disease and vascular eye problems. The use of these injections has become so widespread that most departments around the world (and particularly in the U.K) do not have enough doctors to meet the service provision demands of an ever increasing number of patients. Many departments have trialed training ophthalmic nurse practitioners as a solution and the number of such specifically trained nurses is set to rise exponentially in the future. This book is meant to be an easy to carry A5 handbook detailing all that an ophthalmic nurse practitioner needs to know about performing the procedure. It is hoped that the book will also be of benefit to trainee ophthalmologists learning the procedure.As this is an emerging area of expertise in ophthalmology, currently there exists no other books on the topic. The readers will benefit from having a single resource detailing all that they need to know about the procedure. This means that nurses will not have to cross reference multiple complicated ophthalmic textbooks. As an A5 handbook, it will be easy to carry and reference in clinics. It is deliberately meant to be concise (around 100 pages), thus concentrating only on the core knowledge required.
The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how the vitreous is composed and what role it plays in normal physiology. Over the years, however, many studies have produced independent findings concerning vitreous biochemistry, structure, and physiology. The Vitreous organizes these findings into a well-constructed compendium that not only addresses the most current scientific knowledge, but also reviews historical perspec tives in a manner that lends richness to the scope of the book. The first few chapters present an exhaustive, yet readable, review of the body of scientific data that have come from laboratories and researchers throughout the world. Extensive bibliographies direct interested readers further into specific aspects of the basic science of the vitreous. Chapter II: "Embryology" and Chapter IV: "Structure" present a novel organizational approach to assembling and presenting data in an integrated manner. Chapter V: "Functions" and Chapter VI: "Development and Aging" introduce fresh perspectives on the importance of the vitreous as some thing more than a vestigial space filler within the eye.
This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.
Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. - Shows how the use of nanomaterials can help target a drug to specific tissues and cells - Explores the development of stimuli-responsive drug delivery systems - Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy
Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. - Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems - Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation - Contains extensive references and further reading for course and self-study
A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more - Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology