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Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.
The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.
Based on the breakthrough understanding that virtually all headaches are forms of migraine--because migraine is not a specific type of headache, but the built-in mechanism that causes headaches of all kinds, along with neck stiffness, sinus congestion, dizziness, and other problems--Dr. Buchholz's Heal Your Headache puts headache sufferers back in control of their lives with a simple, transforming program: Step 1: Avoid the "Quick Fix." Too often painkillers only make matters worse because of the crippling complication known as rebound. Step 2: Reduce Your Triggers. The crux of the program: a migraine diet that eliminates the foods that push headache sufferers over the top. Step 3: Raise Your Threshold. When diet and other lifestyle changes aren't enough, preventive medication can help stay the course. That's it: in three steps turn your headache problems around.
Rather than focusing on the sadness and difficulties that followed her diagnosis, Moorhead deals with the practical problems faced by many MS patients: how to parent effectively, stand up to doctors who think she looks 'fine', and what to do with the mixed bag of cognitive difficulties. Moorhead is a real-life person with real-life reactions to MS -- she fights back when people attack her for parking in the handicapped spot even though she looks normal and she faces life with humour that will lift the spirits and encourage others fighting the disease.
Coffee represents a cultural movement that reached its peak during the first decade of the 2000s and reinvented itself in multiple opportunities to maintain its leading role in today's culture. These innovation processes have transformed coffee from a typical artisanal cup of dark, bitter, and hot liquid to a worldwide industry. Nowadays, coffee is usually mixed with spices, liquors, dairy products, and more. Coffee has taken its status as a social beverage to the next level and has made its way into international gastronomy. Although that classic cup of black coffee continues to be a sought-after item, in most establishments specializing in this beverage, a cup of coffee is a work of visual and gustatory art, made by professionals in the field, known as baristas. Coffee has become a powerful industry, and one of its most recent allies is cannabis. The Cannabis industry, on the other hand, has been present in the human culture for millennia, though it had an abrupt interruption at the beginning of the 20th century when classified as an illegal narcotic due to its psychoactive properties. With the availability of new medical research technologies and the progressive easing of use restrictions, both medicinal and recreational, the spotlight is on cannabis as a substance with multiple beneficial effects for health in general. However, this plant should be used with caution, given the absence of knowledge regarding its effects on our organism. Cannabis is on the rise due to its connection with industries such as pharmaceuticals, cosmetics, and recently coffee. Cannabis coffee is a relatively recent topic. Socially speaking, there seems to be a great interest on the part of Cannabis consumers in incorporating the plant or its derivatives in multiple elements of everyday life, as part of meals and even in their morning coffee. However, despite the social interest in quickly adopting this fusion, scientifically, this is a much delicate subject. One of the main components of coffee is caffeine, which has also been cataloged as a psychoactive substance due to the stimulating effect it exerts on the central nervous system. Similarly, cannabinoids, the main chemical components of cannabis, also act on the nervous system, but produce slightly different effects, as both stimulants and depressants, which translates into states of euphoria or relaxation. Thus, the possible effects that the interaction between these two psychoactive substances may have on the organism is the subject of interest for many scientists, due to their presumed action on brain systems as memory and learning. In this book, we explore the link between cannabis and caffeine and those areas of the nervous system impacted by these substances, and the possible effects that could arise from their interaction in the body. Likewise, we will go through the benefits and risks that this combination could bring. Finally, you will learn some anecdotes from users and the homemade ways of preparing this combination of Cannabis and coffee. Join us to explore the exciting link between the two!
A comprehensive, integrated, and accessible textbook presenting core neuroscientific topics from a computational perspective, tracing a path from cells and circuits to behavior and cognition. This textbook presents a wide range of subjects in neuroscience from a computational perspective. It offers a comprehensive, integrated introduction to core topics, using computational tools to trace a path from neurons and circuits to behavior and cognition. Moreover, the chapters show how computational neuroscience—methods for modeling the causal interactions underlying neural systems—complements empirical research in advancing the understanding of brain and behavior. The chapters—all by leaders in the field, and carefully integrated by the editors—cover such subjects as action and motor control; neuroplasticity, neuromodulation, and reinforcement learning; vision; and language—the core of human cognition. The book can be used for advanced undergraduate or graduate level courses. It presents all necessary background in neuroscience beyond basic facts about neurons and synapses and general ideas about the structure and function of the human brain. Students should be familiar with differential equations and probability theory, and be able to pick up the basics of programming in MATLAB and/or Python. Slides, exercises, and other ancillary materials are freely available online, and many of the models described in the chapters are documented in the brain operation database, BODB (which is also described in a book chapter). Contributors Michael A. Arbib, Joseph Ayers, James Bednar, Andrej Bicanski, James J. Bonaiuto, Nicolas Brunel, Jean-Marie Cabelguen, Carmen Canavier, Angelo Cangelosi, Richard P. Cooper, Carlos R. Cortes, Nathaniel Daw, Paul Dean, Peter Ford Dominey, Pierre Enel, Jean-Marc Fellous, Stefano Fusi, Wulfram Gerstner, Frank Grasso, Jacqueline A. Griego, Ziad M. Hafed, Michael E. Hasselmo, Auke Ijspeert, Stephanie Jones, Daniel Kersten, Jeremie Knuesel, Owen Lewis, William W. Lytton, Tomaso Poggio, John Porrill, Tony J. Prescott, John Rinzel, Edmund Rolls, Jonathan Rubin, Nicolas Schweighofer, Mohamed A. Sherif, Malle A. Tagamets, Paul F. M. J. Verschure, Nathan Vierling-Claasen, Xiao-Jing Wang, Christopher Williams, Ransom Winder, Alan L. Yuille
Written by residents for residents, Pocket Neurology, 2nd Edition is your go-to resource for essential neurologic information in a high-yield, easy-to-use format. Concise and well organized, it provides must-know information on hospital- and clinic-based neurologic workup, diagnosis, and management. The second edition of this pocket-sized bestseller delivers highly relevant adult neurologic coverage in an easily portable source. Find what you need quickly and easily with concise text, numerous tables, and bulleted lists throughout. Progress logically from neurologic signs and symptoms to differential diagnosis, workup and diagnosis, assessment of risks and benefits of available treatments, to treatment and prognosis. Focus on the most important, highly relevant facts thanks to a, streamlined presentation that allows for more algorithms, tables, diagrams, and images. Stay up to date in every area of neurology with significantly revised chapters on stroke, epilepsy, dementia, and MS, and more drug dosing information regarding inpatient care. Consult this high-yield handbook by clinical presentation, such as coma, stroke, headaches, and seizures, or by special topic, such as neuroimaging, behavioral neurology, and sleep medicine. Learn from neurology residents and beginning neurology fellows in collaboration with attending neurologists at the Massachusetts General Hospital, Brigham and Women’s Hospital, Children’s Hospital Boston, and Beth Israel Deaconess Medical Center.
In The Man Who Tasted Words, Guy Leschziner leads readers through the senses and how, through them, our brain understands or misunderstands the world around us. Vision, hearing, taste, smell, and touch are what we rely on to perceive the reality of our world. Our senses are the conduits that bring us the scent of a freshly brewed cup of coffee or the notes of a favorite song suddenly playing on the radio. But are they really that reliable? The Man Who Tasted Words shows that what we perceive to be absolute truths of the world around us is actually a complex internal reconstruction by our minds and nervous systems. The translation into experiences with conscious meaning—the pattern of light and dark on the retina that is transformed into the face of a loved one, for instance—is a process that is invisible, undetected by ourselves and, in most cases, completely out of our control. In The Man Who Tasted Words, neurologist Guy Leschziner explores how our nervous systems define our worlds and how we can, in fact, be victims of falsehoods perpetrated by our own brains. In his moving and lyrical chronicles of lives turned upside down by a disruption in one or more of their five senses, he introduces readers to extraordinary individuals, like one man who actually “tasted” words, and shows us how sensory disruptions like that have played havoc, not only with their view of the world, but with their relationships as well. The cases Leschziner shares in The Man Who Tasted Words are extreme, but they are also human, and teach us how our lives and what we perceive as reality are both ultimately defined by the complexities of our nervous systems.
A leading neurologist recounts some of her most astonishing and challenging cases, demonstrating how the study of epilepsy is critical to our understanding of the brain. A “brilliant . . . beautifully humane account” for readers of Oliver Sacks’ The Man Who Mistook His Wife for a Hat (Guardian, Best Books of the Year) Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to solve them: a man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work. In this riveting book, Suzanne O’Sullivan takes you with her as she tracks the clues of her patients’ symptoms. It’s a journey that will open your eyes to the unfathomable intricacies of our brains and the infinite variety of human experience.