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This book was written for the complex scenario of fertility-sparing management in gynaecological cancer. In reproductive age women, appropriate counselling is mandatory in any cancer diagnosis, including discussing the long-term consequences of the different treatment options on fertility and the possibility of fertility preservation. However, women affected by gynaecological cancer must consider that treatment options including hysterectomy and bilateral oophorectomy in most cases. Therefore, in gynaecological cancer, the standard treatment often consists of an inevitable loss of fertility. The direct consequence is that fertility preservation management does not always result in the optimal treatment of the disease, which increases the risk of worsening oncologic outcomes. This book discusses all the elements involved in managing these patients to provide a complete and detailed overview of fertility preservation management options in young women affected by gynaecological cancers. Specifically, this book discusses the role of genetic assessment and counselling, the effect of anticancer treatments for gynaecological cancer on fertility, classic fertility preservation techniques adapted to gynaecological cancer, detailed and specific fertility preservation management for cervical, ovarian, and endometrial cancer, and the role of a multidisciplinary approach in these patients.
The focus of Berek and Hacker's for four editions has been on the application of basic and clinical science to the clinical practice of gynecologic oncology. That approach has been successful and the book has been well received. The Fifth Edition follows the format of the previous editions, with the addition of color. We will also include a fully searchable companion Website that includes an image bank.
This practical handbook provides a comprehensive yet concise guide for fellows, residents, and specialist trainees in the diagnosis and management of gynecologic cancers. The book is easy to read and designed for quick reference, with streamlined data to support treatment recommendations. The chapters have been condensed from the key chapters in Barakat, Markman and Randall's Principles and Practice of Gynecologic Oncology, Fifth Edition and are consistently organized to move from incidence to etiology to diagnosis and treatment. Helpful algorithms and reference tables are included where appropriate. Key points appear in shaded boxes within each chapter.
This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.
This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.
Based on: DeVita, Hellman, and Rosenberg's cancer / editors, Vincent T. DeVita Jr., Theodore S. Lawrence, Steven A. Rosenberg. 9th ed. c2011.
Portable and easy to consult, The Johns Hopkins Manual of Gynecology and Obstetrics is a trusted on-the-spot reference for virtually any issue you’ll encounter in obstetrics, high-risk obstetrics, gynecology, reproductive endocrinology, infertility, and gynecologic oncology. The updated 6th Edition has been reorganized for quick reference, and contains thoroughly revised information culled from the collective expertise of residents and attending physicians at The Johns Hopkins University.