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This book is projected as a preliminary manuscript in Infectious Disease. It is undertaken to cover the foremost basic features of the articles. Infectious Disease and analogous phenomenon have been one of the main imperative postwar accomplishments in the world. The book expects to provide its reader, who does not make believe to be a proficient mathematician, an extensive preamble to the field of infectious disease. It may immeasurably assist the Scientists and Research Scholars for continuing their investigate workings on this discipline. Numerous productive and precise illustrated descriptions with a number of analyses have been included. The book offers a smooth and continuing evolution from the principally disease oriented lessons to a logical advance, providing the researchers with a compact groundwork for upcoming studies in this subject.
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
This book gives a comprehensive overview of recent trends in infectious diseases, as well as general concepts of infections, immunopathology, diagnosis, treatment, epidemiology and etiology to current clinical recommendations in management of infectious diseases, highlighting the ongoing issues, recent advances, with future directions in diagnostic approaches and therapeutic strategies. The book focuses on various aspects and properties of infectious diseases whose deep understanding is very important for safeguarding human race from more loss of resources and economies due to pathogens.
The book discusses different therapeutic approaches based on different mathematical models to control the HIV/AIDS disease transmission. It uses clinical data, collected from different cited sources, to formulate the deterministic as well as stochastic mathematical models of HIV/AIDS. It provides complementary approaches, from deterministic and stochastic points of view, to optimal control strategy with perfect drug adherence and also tries to seek viewpoints of the same issue from different angles with various mathematical models to computer simulations. The book presents essential methods and techniques for students who are interested in designing epidemiological models on HIV/AIDS. It also guides research scientists, working in the periphery of mathematical modeling, and helps them to explore a hypothetical method by examining its consequences in the form of a mathematical modelling and making some scientific predictions. The model equations, mathematical analysis and several numerical simulations that are presented in the book would serve to reveal the consequences of the logical structure of the disease transmission, quantitatively as well as qualitatively. One of the chapters introduces the optimal control approach towards the mathematical models, describing the optimal drug dosage process that is discussed with the basic deterministic models dealing with stability analysis. Another one chapter deals with the mathematical analysis for the perfect drug adherence for different drug dynamics during the treatment management. The last chapter of the book consists the stochastic approach to the disease dynamics on HIV/AIDS. This method helps to move the disease HIV/AIDS to extinction as the time to increase. This book will appeal to undergraduate and postgraduate students, as well as researchers, who are studying and working in the field of bio-mathematical modelling on infectious diseases, applied mathematics, health informatics, applied statistics and qualitative public health, etc. Social workers, who are working in the field of HIV, will also find the book useful for complements.
Since most research activities involve laboratory work, there is need for efficient management of laboratory or test facilities to ensure quality-controlled research and cost-effective use of resources. It is obvious that good laboratory and research management skills are necessary for scientists and scholars involved directly or indirectly in industrial, clinical, or bioscience research and/or charged with management of laboratory facilities. The essence of this write-up is therefore to enhance good laboratory management practices that ensure stressless compliance with legal and regulatory frameworks for health and safety. The aim is to promote scientific excellence by highlighting the conditions and skills necessary for efficient and innovative management of laboratory facilities while enhancing consciousness and efficacy in cost-effective research management. The issues addressed in the book include a proposal of the administrative setup of a laboratory or test facility, laboratory design considerations, which obviously have a significant impact on the quality of results generated. The principles of good laboratory practices and the importance of biosafety and biosecurity are specially addressed. The author also reiterates the importance of a procurement strategy for each laboratory or test facility, whose aim should be to set out a planned approach for cost-effective purchasing of required goods and services, taking into account several factors such as the timeline for procurement, the funding and budget and the projected risks and opportunities. Here, the need for a defined and documented policy and procedures for selection and use of purchased external goods and services in addition to an inventory control system for laboratory supplies is highlighted. Laboratory operators need to have an overview of different categories and types of laboratory equipment at their disposal with good knowledge of their safe handling, operation, and maintenance following well-set schedules. Besides this concern, the book also dwells on laboratory information management system (LIMS), which is an important and integral part of laboratory operations relevant for efficient laboratory management. A whole chapter is consecrated to quality control (QC), quality assurance (QA) and total quality management (TQM) as the three major elements of quality, which effectively sets the stage for laboratory accreditation, which demonstrates legitimacy and credibility of research results. In fact, laboratory accreditation is the process by which an independent and authorized agency certifies the quality system and competence of a laboratory on the basis of certain predefined standards. It is the formal recognition, authorization, and registration of a laboratory that has demonstrated its capability, competence and credibility to carry out the tasks it is claiming to be able to do. In this book, the reader will discover the whole process of laboratory accreditation with the various agencies involved as well as the benefits of laboratory accreditation. The book closes up with ethical issues in research management. It is obvious that the consideration of ethics in research should enhance mature decision-making in harmony with changing technology. The chapter on this issue points out the fact that efficient research and laboratory management must be based on ethical principles that guarantee all stakeholders access to the benefits of new technologies with increased understanding of biological systems and responsible use of technology. Some basic guidelines are given at the end on how to implement knowledge gained from the book to efficiently run a modern laboratory or research facility.
This book collects select papers presented at the “International Conference on Mathematical Analysis and Application in Modeling,” held at Jadavpur University, Kolkata, India, on 9–12 January 2018. It discusses new results in cutting-edge areas of several branches of mathematics and applications, including analysis, topology, dynamical systems (nonlinear, topological), mathematical modeling, optimization and mathematical biology. The conference has emerged as a powerful forum, bringing together leading academics, industry experts and researchers, and offering them a venue to discuss, interact and collaborate in order to stimulate the advancement of mathematics and its industrial applications.
This book focuses on the effects of rural livelihood and the impact of infectious diseases on health and poverty. It explores cultures and traditions in developing countries and their role in infectious-disease management and prevention. It highlights the associated healthcare systems and how these have contributed to some of the challenges faced, and goes on to elaborate on the significance of community involvement in infectious-disease prevention, management and control. It also emphasizes the importance of surveillance and setting up strategies on infectious-disease management that are favourable for poor communities and developing countries. Infectious Diseases and Rural Livelihood in Developing Countries allows students, researchers, healthcare workers, stakeholders and governments to better understand the vicious cycle of health, poverty and livelihoods in developing countries and to develop strategies that can work better in these regions.
Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field
This book introduces a novel approach to comprehending and assessing oxidative stress and antioxidant activity as fundamental components in both health and disease. It explores the advantages and peculiarities of innovative electrochemical methods for estimating and monitoring these processes. Recognizing the electrochemical nature of oxidative stress, the book advocates for electrochemical methods as the preferred means of determination. A central focus of the book is the presentation of a new electrochemical method for evaluating oxidative stress and antioxidant activity: potentiometric determination. The book presents results of antioxidant activity analyses for both healthy individuals and patients with diverse pathologies. Additionally, the book discusses the prospective advantages of employing potentiometry as a monitoring tool in areas such as diet, sports, and wellness. Further considerations extend to the future applications of oxidative stress monitoring, encompassing wearable devices, sensors, non-invasive assessments, and telemedicine. In short, this book establishes the method's credibility as a diagnostic criterion for studying oxidative stress across laboratory settings, bedside applications, and everyday life.
This book discusses several mathematical models highlighting the disease dynamics of psoriasis and its control. It explains the control of keratinocyte concentration through a negative feedback mechanism and the effect of including a realistic time delay in that system. The effect of cytokine release is described in a mathematical model of psoriasis and further elucidated in two different mathematical pathways: the ordinary differential equation model system, and the fractional-order differential equation model system. The book also identifies the role of CD8+ T-cells in psoriasis by investigating the interaction between dendritic cells and CD8+ T-cells. Presenting an approach to control the fractional-order system to prevent excess production of keratinocyte cell population, the book is intended for researchers and scientists in the field of applied mathematics, health informatics, applied statistics and qualitative public health, as well as bio-mathematicians interested in the mathematical modeling of autoimmune diseases like psoriasis.