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This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.
The goal of a high quality, cost-effective and accessible health care for patients is achieved through constructing a team-based and patient-centered health care delivery system. The expanded role of pharmacists uplifts them to patient care from dispensing and manufacturing or marketing of drugs. Along with doctors and allied health professionals, pharmacists are increasingly recognized as an integral part of the patient care team. Furthermore, colleges of pharmacy need to revise and up-date their curricula to accommodate the progressively increasing development in the pharmaceutical education and the evolving new roles of practicing pharmacists in patient care settings. This book focuses on the expanded role of the pharmacists in total patient care including prescribing, dispensing, compounding, administering and monitoring of drugs at home, hospital, community, hospice, critical care, changeover and other care settings. The sector is emerging in both developed and under-developed countries. Overburdened by patient loads and the explosion of new drugs physicians turned to pharmacists more and more for drug information especially within institutional settings. And today’s patient care pharmacists are taking more interests in medication review and reconciliation, patient education and counseling, creating drug therapy regimen and monitoring compliance. The purpose of this book is to guide the pharmacists in their daily interactions with patients and to ensure collaboration with other health professionals. The contents are mostly based on recently published articles related to patient care, with most recent ideas and activities followed by the patient care pharmacists around the globe. However, a pharmacist implements the care plan in collaboration with other health care professionals and the patient or caregiver. Along with professional guidelines, the book discusses the concepts and best practices of patient interaction, patient rights, and ethical decision-making for the professional pharmacist, apprentice and student. In every chapter, the role of pharmacists in that chapter specific issues are detailed explicitly so that a professional pharmacist or a student can figure out his or her do’s and don’ts in that specific situation. Moreover, further reading references are listed as future recommendations. So, the book is an archive of potential references too. Among so many books about patient care, either doctors’ or nurses’ roles are highlighted. The proposed book highlights the pharmacists’ roles and responsibilities to the most, separated from those of doctors and nurses, with the most recent information obtained from most publications in several journals, books, bulletins, newsletter, magazines etc.
Be ready to prescribe and administer drugs safely and effectively, with the fully updated Pharmacotherapeutics for Advanced Practice, 5th Edition. Anchored in pharmacology and the principles of therapeutics, and written by experts in the field, this is your road map to effective drug therapies. Learn to correctly identify a disorder, review the drugs used to treat it, and select the optimal therapy. With expert direction on more than 50 common disorders, this is the ideal resource for advanced practice clinicians and students learning pharmacotherapeutics, and a go-to reference for experienced clinicians.
To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.
Providing a selection of critical pieces on the key challenges and debates in student engagement in higher education, this edited collection of sector-leading, scholarly-informed critical reflections is designed to consider and build upon what can be done to advance student engagement. By problematising student engagement practice, this book explores how to strengthen policies, recognise the issues and create solutions to overcome barriers and tensions. It considers topics such as diversity, accessibility, representativeness, evidencing impact, data analytics, the campus estate and the impact of COVID-19. The contributors provide lessons learned and knowledge from the field to make practice with students more considered and robust for the challenges ahead in the post-pandemic university. Moving beyond endorsing student engagement and offering best practice to critically reflect on and challenge our engagements with students in contemporary higher education, this book is ideal reading for all those developing education, course leaders and heads of academic departments, as well as anyone interested in advancing student engagement in their higher education setting.
This definitive guide provides readers with an overview of multifunctional nanoparticles, delving into their novel synthesis methods, unique properties, and diverse applications in therapy, biology, and pharmacy. It also explores techniques for synthesizing magnetic nanoparticles and explains how to tailor nanoparticles with desired traits. Multifunctional Magnetic Nanoparticles in Therapy, Biology, and Pharmacy: Synthesis, Fundamentals and Applications, explores established and emerging techniques for synthesizing magnetic nanoparticles, enabling readers to understand how to tailor-make nanoparticles with desired traits. Beginning with fundamentals, leading experts delve into topics like recent trends in nanoparticle fabrication, magnetic properties, drug delivery systems, imaging, sensing, separation techniques, toxicity mitigation, and commercial applications. The book showcases the transformative impact and future possibilities of multifunctional magnetic nanoparticles in therapy, biology, and pharmacy. It elucidates the fundamentals behind their magnetic properties and interactions, empowering the development of innovative applications. Detailed chapters highlight their utilization in hyperthermia, cancer therapies, separation and detection of biological molecules and cells, as biocatalysts and in bionanotechnology, antimicrobial agents, sensors, and more. This book is written primarily for scientists, researchers, and engineers working in the fields of nanotechnology, materials science, biomedical engineering, and pharmaceutical sciences. The book covers core principles as well as practical applications, which makes it a valuable textbook or training resource across academic and professional settings in this field.
3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.
The financial sector is witnessing rapid technological innovations, leading to the emergence of Fintech (financial technologies), revolutionizing national and international financial landscapes. Fintech is expanding and enhancing financial products and services, making them more accessible and affordable while transforming customer relationships, payment methods, financing, and transfers. Advances in Emerging Financial Technology and Digital Money provides a platform for collective reflection, bringing together institutions, policymakers, digital and financial service providers, professionals, and academics from various disciplines. The aim is to clarify the challenges, opportunities, and socio-economic impacts of innovations in finance and technology on citizens and businesses in Morocco, Africa, and worldwide. This comprehensive collection offers valuable insights into the current state and prospects of financial technology and digital money. This book covers all the essential topics, including: AI and Machine Learning in Fintech and Beyond Financial Inclusion, Literacy, and Behavior Fintech Ecosystems, Collaboration, and Analysis Blockchain, Security, and Sustainability Fintech Innovations and Applications In this new book, the authors share their experiences to provide a comprehensive and well‐researched overview of the technologies and concepts that will transform the banking industry as we know it. It aspires to be a useful reference for executive managers, CIOs, Fintech professionals, and researchers interested in exploring and implementing an efficient Fintech strategy. The book also presents selected papers from International Fintech Congress (IFC 2022).
This report reviews the important role of medicines in health sytems, describes recent trends in pharmaceutical expenditure and financing, and summarises the approaches used by OECD countries to determine coverage and pricing.