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"What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are."--Provided by the publisher.
Innate Terrain surveys landscape architecture from across Canada, documenting the inspiring breadth of contemporary projects.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation. Provides insights into the fundamental homeostatic processes vis-à-vis stressors to help in investigation Illustrates the depicted tenets and how to offset them against established models of response to physical and psychotic stressors in both animals and humans Covers the crucial issue of the immune response to endocrine disruptors Includes immunological parameters as reporter system of environmental adaptation Provides many illustrative examples to foster reader understanding
This book summarizes the latest research findings in the neurocircuitry of innate behaviors, covering major topics such as innate fear, aggression, feeding, reward, social interaction, parental care, spatial navigation, and sleep-wake regulation. For decades, humans have been fascinated by wild animals’ instincts, like the annual two-thousand-mile migration of the monarch butterfly in North American, and the “imprint” behavior of newborn birds. Since these instincts are always displayed in stereotypical patterns in most individuals of a given species, the neural circuits processing such behaviors must be genetically hard-wired in the brain. Recently, with the development of modern techniques, including optogenetics, retrograde and anterograde virus tracing, and in vivo calcium imaging, researchers have been able to determine and dissect the specific neural circuits for many innate behaviors by selectively manipulating well-defined cell types in the brain. This book discusses recent advances in the investigation of the neural-circuit mechanisms underlying innate behaviors.
The first volume in an historic and noteworthy 6-volume series containing many of the first English translations of the classic mahamudra literature compiled by the Seventh Karmapa. Sounds of Innate Freedom: The Indian Texts of Mahamudra is an historic six-volume series containing many of the first English translations of classic Mahamudra literature. The texts and songs in these volumes constitute the large compendium called The Indian Texts of the Mahamudra of Definitive Meaning, compiled by the Seventh Karmapa, Chötra Gyatso (1456–1539). Mahamudra refers to perfect buddhahood in a single instant, the omnipresent essence of mind, nondual and free of obscuration. This collection offers a brilliant window into the richness of the vast ocean of Indian Mahamudra texts, many cherished in all Tibetan lineages, particularly in the Kagyü tradition, giving us a clear view of the sources of one of the world’s great contemplative traditions. This first volume in publication contains the majority of songs of realization, consisting of dohas (couplets), vajragitis (vajra songs), and caryagitis (conduct songs), all lucidly expressing the inexpressible. These songs offer readers a feast of profound and powerful pith instructions uttered by numerous male and female mahasiddhas, yogis, and dakinis, often in the context of ritual ganacakras and initially kept in their secret treasury. Displaying a vast range of themes, styles, and metaphors , they all point to the single true nature of the mind—mahamudra—in inspiring ways and from different angles, using a dazzling array of skillful means to penetrate the sole vital point of buddhahood being found nowhere but within our own mind. The beautifully translated texts brilliantly capture the wordplay, mystical wonder, bliss, and ecstatic sense of freedom expressed by awakened Mahamudra masters of India. It includes works by Saraha, Mitrayogi, Virupa, Tilopa, Naropa, Maitripa, Nagarjuna, the female mahasiddhas princess Laksmimkara and Dombiyogini, and otherwise unknown awakened figures of this rich tradition. Reading and singing these songs that convey the inconceivable and contemplating their meaning in meditation will open doors to spiritual experience for us today just as it has for countless practitioners in the past.
Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.
For hundreds of years, different leadership theories have been explored to try to explain exactly how and why certain people become great leaders. Research spans a discussion of personality traits, the characteristics of the situation at hand, and qualifications of the leader to try to determine what causes people to become more likely than others to take charge. This can be in various settings: CEOs, presidents and prime ministers, managing directors, governors, senators, head coaches, and more. Through the examination of first-time leadership, new theories and ideas on leadership are explored. The Handbook of Research on Innate Leadership Characteristics and Examinations of Successful First-Time Leaders is a comprehensive reference source that focuses on what qualities distinguish first-time leadership from traditional leaders, while furthering leadership theories that look at other variables such as situational factors, knowledge base, skill levels, etc. It reviews the various approaches used by first-time leadership and how each of them uniquely approaches effective leadership, key outcomes, and the strengths and weaknesses of each approach. Furthermore, it distinguishes between the traditional route for leadership, the gradual moving up of an individual over time to higher positions, and a first-time leadership in which an individual begins right away in a position without climbing the professional ladder. This book will attempt to draw lessons from existing first-time leadership experience and provide evidence for the appropriateness of such a route to leadership. Topics highlighted include transformational leadership, political leaders, ethical and unethical leadership, and leadership development. This book is ideal for young professionals, leaders, executives, managers, graduate students, practitioners, government officials, researchers, academicians, and students.