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Neurocognitive and neuropsychiatric disorders contribute to a substantial amount of global morbidity and, as such, the identification of their causes is paramount to understanding their underlying pathophysiology as well as treatment and prevention strategies. Infectious Diseases in Neurocognitive and Neuropsychiatric Medicine considers the many infectious diseases that have been associated with cognitive and neuropsychiatric function. In Parts I-III, each chapter focuses on a different disease to cover a range of viral, bacterial, and parasitic diseases in neurocognitive and neuropsychiatric medicine. Part IV considers infectious diseases and clinical conditions and syndromes, while Part V examines the relationship between neurocognitive and neuropsychiatric function and the microbiome and Part VI the relationship with childhood development. In addition to molecular and clinical descriptions of the infectious diseases themselves, many chapters also explore the diseases' basic epidemiological features to consider where they may be exerting the greatest impact on cognitive and neuropsychiatric function. Where they exist, the possible mitigating factors and treatments for the neuropsychiatric and cognitive dysfunction that can be associated with these infectious diseases are also explored. In doing so, this volume examines the neurocognitive and neuropsychiatric disorders associated with infectious disease to better understand the role infections play.
The guideline offers clear, concise, and actionable recommendation statements to help clinicians to incorporate recommendations into clinical practice, with the goal of improving quality of care. Each recommendation is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms.
Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer’s and Parkinson’s diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality–behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the latest findings in the field and includes chapters on delusional symptoms, mood disorders and neurotic symptoms, cognitive impairment, behavioral and personality changes, and recently, cerebral alterations revealed in PTSD patients and in endogenous psychoses through neuroimaging and neuropathology. These findings will certainly widen the realm of neuropsychiatry going forward and will prove of great value to specialists as well as to academics and trainees in neurology, psychiatry, neuropsychology, neuroradiology, neuropathology, neurophysiology, neurochemistry, and clinical genetics. Ultimately, neuropsychiatry aims to prevent and reduce the suffering of individuals with the psychiatric symptoms of cerebral disorders.
A 1996 survey of the members of the American Board of Professional Psychology Diplomates, published by The Clinical Neuropsychologist journal, selected the first edition of this book as one of the "Essential Books and Journals in North American Clinical Neuropsychology"--a list which included only 10 other titles! The Second Edition has improved further on this high standard. While the authors have retained the same general structure--with the addition of a set of three chapters on psychosocial outcomes--virtually the entire book has been rewritten and thoroughly updated to reflect recent developments in this area of knowledge. Part I features new chapters on the Iowa-Benton approach, on cognitive screening methods, and on computers and memory. Part II has been expanded with new chapters on Tourette's syndrome, acute and chronic hypoxemia, HIV infection, schizophrenia, Huntington's disease, and an expanded chapter on Parkinson's disease. Part III is entirely new, and it focuses on life quality outcome in head injury and pulmonary disease. Considerably enlarged in size, this book will remain the basic reference on the neuropsychological aspects of diseases affecting brain and behavior.
Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online. In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade’s advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.
This issue of Critical Care Clinics focuses on Psychiatric Aspects of Critical Care Medicine. Editor Jose Maldonado has assembled an expert team of authors on topics such as: Psychiatric Aspects of Organ Transplantation in Critical Care; Medical Complications of Psychiatric Treatment; Psychiatric and Palliative Care in the ICU; Psychiatric Aspects of Heart and Lung Disease in Critical Care; Alcohol Withdrawal Syndromes: Assessment and Management; Substance Abuse and Withdrawal in the Critical Care Setting; Mood Disorders and The Outcome of Suicidal Thoughts and Attempts; Anxiety Disorders and the Outcomes of Trauma; Assessment and Management of Toxidromes in the Critical Care Unit; Neuropsychiatric Consequences of Trauma and Head Injury; Detection and Management of Pre-Existing Cognitive Impairment in the Critical Care Unit; Delirium: Pathophysiology, Diagnosis and Treatment; Neuropsychiatric Aspects of Infectious Processes.
Disturbances of various domains of cognitive function have been shown to provide a major determinant of outcome for patients with psychiatric conditions. Cognitive impairment is present in an array of diseases, including schizophrenia (with its prodromal stage), mood disorder, autism spectrum disorder, obsessive-compulsive disorder, anxiety disorder, post-traumatic disorder, and eating disorder. In an effort to develop effective therapeutics for cognitive impairment, bridging of preclinical and clinical evidence has been attempted. This edited Book will provide a forum for researchers and clinicians interested in the phenomenology, underlying mechanisms, and treatment of cognitive impairment associated with psychiatric illnesses. Twenty-eight contributions from 8 countries in Europe, Middle East, Asia, North America, and South America represent studies dealing with genetic, molecular, imaging, physiological, psychological, and behavioral issues. Information in this Book will facilitate the development of therapeutics of greater clinical value.
This state-of-the-science reference and text has given thousands of practitioners and students a strong foundation in understanding and treating addictive disorders. Leading experts address the neurobiology of addictions and review best practices in assessment and diagnosis. Specific substances of abuse are examined in detail, with attention to real-world clinical considerations. Issues in working with particular populations--including polysubstance abusers, culturally diverse patients, older adults, chronic pain sufferers, and others--are explored. Chapters summarize the theoretical and empirical underpinnings of widely used psychosocial and pharmacological treatments and clearly describe clinical techniques. New to This Edition *Incorporates a decade's worth of major advances in research and clinical practice. *Updated for DSM-5. *Many new authors; extensively revised with the latest information on specific biological mechanisms, substances, populations, and treatments. *Chapter on motivational interviewing.
Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances. - Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions - Fills an existing gap in the literature by serving as a "one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse - Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references - Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body
The third edition of Psychiatric Care of the Medical Patient brings a classic reference text into the twenty-first century. It combines critical scholarship with the voice of expert clinicians who work at the interface of psychiatry with medical specialties. It is meant to be read for pleasure as well as consulted as a reference. The editors have worked with the authors to bring a consistent perspective to the book - one that sees the medical psychiatrist as an agent for bringing a more comprehensive perspective to medical care. Even seasoned and knowledgeable practitioners will find much that is new to them in this book. The volume covers topics in depth that other books in the field may not cover at all, such as the use of herbal and nutritional therapies for medical-psychiatric symptoms and syndromes, and the choice of questionnaires to supplement history-taking. It looks at old topics in a new way: The chapter on the physical examination applies psychometric considerations to the Babinski sign, describes the method and application of quantitative bedside olfactory testing, and discusses smartphone apps to improve the sensitivity of the examination. Psychiatric Care of the Medical Patient, 3rd Edition provides concepts and information to facilitate the dialogue between psychiatrists and general medical specialists - minimizing psychiatric jargon and speaking in the common language of caring and curious physicians.