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The mystery of inheritance has captivated thinkers since antiquity, and the unlocking of this mystery—the development of classical genetics—is one of humanity’s greatest achievements. This great scientific and human drama is the story told fully and for the first time in this book. Acclaimed science writer James Schwartz presents the history of genetics through the eyes of a dozen or so central players, beginning with Charles Darwin and ending with Nobel laureate Hermann J. Muller. In tracing the emerging idea of the gene, Schwartz deconstructs many often-told stories that were meant to reflect glory on the participants and finds that the “official” version of discovery often hides a far more complex and illuminating narrative. The discovery of the structure of DNA and the more recent advances in genome science represent the culmination of one hundred years of concentrated inquiry into the nature of the gene. Schwartz’s multifaceted training as a mathematician, geneticist, and writer enables him to provide a remarkably lucid account of the development of the central ideas about heredity, and at the same time bring to life the brilliant and often eccentric individuals who shaped these ideas. In the spirit of the late Stephen Jay Gould, this book offers a thoroughly engaging story about one of the oldest and most controversial fields of scientific inquiry. It offers readers the background they need to understand the latest findings in genetics and those still to come in the search for the genetic basis of complex diseases and traits.
Sgt. Juliette Worth is recuperating on the cold case squad where she discovers a disturbing connection between disappearances of pretty girls.
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
LIFE, NOT DEATH, DROVE JUBAL YOUNG . . . but memories of his ma and pa, and his beautiful, bright sister are all he has left. Memories of the peaceful days before Jubal stumbled home with his .22, his blood running cold with fear, terror, and anger. When it was over, the homestead was half burned to the ground. Someone had to bury the bodies. Someone had to set things right. Now, as Jubal rides west into New Mexico, he remembers his family’s laughter and love, his pa’s wisdom, ma’s thick books, and everything that was defiled by a band of drunken renegades towed along by one man’s murderous grudge. A reprobate lawman won’t believe his story. A soft-hearted mountain man won’t survive Jubal’s one-man war. And a judge and his beautiful daughter cannot stop Jubal from climbing a peak of blood and madness: for justice, or payback, or something he can live for—or die for—redeeming. An American film icon delivers a great American novel with Payback at Morning Peak. Gene Hackman, whose fiction is “rousing” (Publishers Weekly) and “robust” (Winston-Salem Journal), takes readers on a powerful and historically dead-on western odyssey in the tradition of Louis L’Amour.
Ageless Questis a personal, sometimes controversial, account of the pursuit of a genetic †̃cure' for aging by an expert in the field. The author is the Novartis Professor of Biology at the Massachusetts Institute of Technology. Aging has always been regarded as a highly complex process with many degenerative changes leading to the cessation of life. But recent research has identified a relatively simple mechanism that governs the pace of aging. Lenny Guarente's Ageless Questis a scientific detective story for the baby boom generation. It offers an insider's view of an area of potentially astonishing high reward—and equally high risk.
Originally published: Great Britain: Short Books, 2013.
If you have ever added a few extra pounds, spent too much time on the couch, damaged a relationship, alienated a coworker, or just simply felt burnt out, you know, first hand, the angst, guilt, and frustration of ill-health. Theres often a gap between the life we desire and the life we live. Pause Points is written to help us bridge this very real gap. In its pages, we discover Seven Essentials of Health and Well-Being: Love the Ones Youre With Fill Your Mind with the Best Bring Out the Best in Others Eat Mindfully Exercise Faithfully Find Peace and Relaxation Connect with the Creator With these Essentials in mind, Dr. Harker introduces us to Pause Pointsan experiential process designed to help us find the closeness, peace, and satisfaction we desire. Through a series of exercises, we learn to slow our pace, reflect, dream, plan, connect, and experience a new positive trajectory in life. Join the growing revolution of those who desire to flourish. Refusing to settle, they seek the very best, striving to get the most out of each day.
A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.
Happiness Genes proves that there is a definitive link between science and spirituality--that you are biologically wired for natural happiness. You have a constitutional right to "life, liberty, and the pursuit of happiness." And every day thousands of advertising images seduce you into believing that happiness can be bought. Put away your wallet. Happiness is at your fingertips--it's sitting right in your DNA. The new science of epigenetics reveals that there are reserves of natural happiness within your DNA that can be controlled by you, your emotions, beliefs, and your behavioral choices. Happiness Genes: Unlock the Positive Potential Hidden in Your DNA examines the nature and source of happiness, from ancient times to the present. It presents the epigenetic and other biological research that shows that DNA contains genes for natural happiness and your ultimate well-being. Then it details the 28-Day natural happiness program--you'll learn how to "switch on" your happiness genes, creating a biological cascade of well-being.
The Positive Mental Moxie of Myth for Personal Growth Joseph Campbell defined a myth as "a life-shaping image, a metaphor that creates a hero out of those who heed it." Author Dr. Gene Landrum takes Campbell's definition one step further by offering a variety of motivational techniques that will propel you to heroic success. Dr. Landrum describes the "superman syndrome" as a series of common behaviors that permit an otherwise average person to rise above the norm. He points out that some of the world's most renowned visionaries--Catherine the Great, Walt Disney, and Ian Fleming--did not conform to tradition because they modeled their behavior on heroic ideals and mythical mentors. Learn how to transform your life from ordinary to extraordinary by focusing on several key ideas: Chasing money is entropic and the path to the poorhouse Happiness is a side effect of being--never trying Romance only comes to those not trying to find romance Anxiety is a by-product of unrealistic expectations Breakdown leads to breakthrough Being stupid is the pathway to being smart Do you have the Superman Syndrome? Test yourself to find out!