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This book describes the vast variety of xenobiotics, such as pesticides, antibiotics, antibiotic resistance genes, agrochemicals and other pollutants, their interactions with the soil environment, and the currently available strategies and techniques for soil decontamination and bioremediation. Topics covered include: transport mechanisms of pollutants along the Himalayas; use of earthworms in biomonitoring; metagenomic strategies for assessing contaminated sites; xenobiotics in the food chain; phyto-chemical remediation; biodegradation by fungi; and the use of enzymes and potential microbes in biotransformation. Accordingly, the book offers a valuable guide for scientists in the fields of environmental ecology, soil and food sciences, agriculture, and applied microbiology.
Our interest in the microbial biodegradation of xenobiotics has increased many folds in recent years to find out sustainable ways for environmental cleanup. Bioremediation and biotransformation processes harness the naturally occurring ability of microbes to degrade, transform or accumulate a wide range of organic pollutants. Major methodological breakthroughs in recent years through detailed genomic, metagenomic, proteomic, bioinformatic and other high-throughput analyses of environmentally relevant microorganisms have provided us unprecedented insights into key biodegradative pathways and the ability of organisms to adapt to changing environmental conditions. The degradation of a wide spectrum of organic pollutants and wastes discharged into the environment by anthropogenic activities is an emerging need today to promote sustainable development of our society with low environmental impact. Microbial processes play a major role in the removal of recalcitrant compounds taking advantage of the astonishing catabolic versatility of microorganisms to degrade or transform such compounds. New breakthroughs in sequencing, genomics, proteomics, bioinformatics and imaging are generating vital information which opens a new era providing new insights of metabolic and regulatory networks, as well as clues to the evolution of degradation pathways and to the molecular adaptation strategies to changing environmental conditions. Functional genomic and metagenomic approaches are increasing our understanding of the relative importance of different pathways and regulatory networks to carbon flux in particular environments and for particular compounds. New approaches will certainly accelerate the development of bioremediation technologies and biotransformation processes in coming years for natural attenuation of contaminated environments
This book is compilation of studies related with the xenobiotics i.e. chemical or other substance that is not normally found in the ecosystems and get accumulated at higher concentration in the biological system due to rampant industrialisation and urbanisation activities. This book has tried to give information on various issues to give comprehensive and concise knowledge of the recent advancement in the field of environmental xenobiotics and how it disturbs the plants metabolism. Other key features of the book are related to xenobiotic toxicity and detoxification mechanism, biochemical tools toward its remediation processes, molecular mechanism for xenobiotics detoxification and effect on metallomics. It also focuses on recent development in the field of waste water remediation concerned with the xenobiotics involvement. This book is different in such a way that it includes all the initial information along with the new researches. It includes the description of problem along with its solution. This volume describe the effects of xenobiotics at different levels i.e. biochemical, physiological and molecular, giving the details on signaling pathways to modify the responses of xenobiotics in plant system. Thus, it gives confirming crosstalk between xenobiotic effects and signalling pathways. This book includes description about both the organic contaminants such as pesticides, solvents and petroleum products as well as inorganic xenobiotics that include heavy metals, non-metals, metalloids, and simple soluble salts. Here the plant is main objective and that have to deal with these kinds of compounds either by avoiding accumulation of these compounds or by exhibiting several enzymatic reactions for detoxification including oxidation, reduction, and conjugation reactions. Affected plants exhibit several enzymatic and non-enzymatic antioxidant and other reactions for detoxification of ROS including oxidation, reduction, hydrolysis and conjugation reactions. The book focuses on different forms and sources of xenobiotics including organic and inorganic xenobiotics. The matter of this book will definitely increase the knowledge about the impacts of xenobiotics on plants system. There must be potentially broad readership who could find this fruitful for their study as well as for their research. As this book has balance between basic plant physiology and toxicity caused by the xenobiotics so it can be widely used in several disciplines. Overall, the book will bring deep knowledge in the field of xenobiotics toxicity in plants during recent years and it is definitely a compilation of interesting information which isn't fully covered elsewhere in the current market.
Microbial Biodegradation and Bioremediation brings together experts in relevant fields to describe the successful application of microbes and their derivatives for bioremediation of potentially toxic and relatively novel compounds. This single-source reference encompasses all categories of pollutants and their applications in a convenient, comprehensive package. Our natural biodiversity and environment is in danger due to the release of continuously emerging potential pollutants by anthropogenic activities. Though many attempts have been made to eradicate and remediate these noxious elements, every day thousands of xenobiotics of relatively new entities emerge, thus worsening the situation. Primitive microorganisms are highly adaptable to toxic environments, and can reduce the load of toxic elements by their successful transformation and remediation. - Describes many novel approaches of microbial bioremediation including genetic engineering, metagenomics, microbial fuel cell technology, biosurfactants and biofilm-based bioremediation - Introduces relatively new hazardous elements and their bioremediation practices including oil spills, military waste water, greenhouse gases, polythene wastes, and more - Provides the most advanced techniques in the field of bioremediation, including insilico approach, microbes as pollution indicators, use of bioreactors, techniques of pollution monitoring, and more
Ecological Impacts of Toxic Chemicals presents a comprehensive, yet readable account of the known disturbances caused by all kinds of toxic chemicals on both aquatic and terrestrial ecosystems. Topics cover the sources of toxicants, their fate and distribution through the planet, their impacts on specific ecosystems, and their remediation by natural systems. Each chapter is written by well-known specialists in those areas, for the general public, students, and even scientists from outside this field. The book intends to raise awareness of the dangers of chemical pollution in a world dominated by industry and globalization of resources. Because the problems are widespread and far reaching, it is hoped that confronting the facts may prompt better management practices at industrial, agricultural and all levels of management, from local to governmental, so as to reduce the negative impacts of chemical contaminants on our planet.
Smart Bioremediation Technologies: Microbial Enzymes provides insights into the complex behavior of enzymes and identifies metabolites and their degradation pathways. It will help readers work towards solutions for sustainable medicine and environmental pollution. The book highlights the microbial enzymes that have replaced many plant and animal enzymes, also presenting their applications in varying industries, including pharmaceuticals, genetic engineering, biofuels, diagnostics and therapy. In addition, new methods, including genomics and?metagenomics, are being employed for the discovery of new enzymes from microbes. This book brings all of these topics together, representing the first resource on how to solve problems in bioremediation. Provides the most novel approaches in enzyme studies Gives insights in real-time enzymology that are correlated with bioremediation Serves as a valuable resource on the use of genomes, transcriptomes and proteomes with bioremediation Refers to enzymes as diagnostic tools
This new edition is revised throughout and includes new and expanded information on natural resource damage assessment, the latest emerging contaminants and issues, and adds new international coverage, including case studies and rules and regulations. The text details key environmental contaminants, explores their fates in the biosphere, and discusses bioaccumulation and the effects of contaminants at increasing levels of ecological organization. Vignettes written by experts illustrate key themes or highlight especially pertinent examples. This edition offers an instructors' solution manual, PowerPoint slides, and supplemental images. Features: Adds all new discussions of natural resource damage assessment concepts and approaches Includes new vignettes written by leading guest authors Draws on materials from 2,500 cited sources, including 400+ new to this edition Adds numerous new entries to a useful glossary of 800+ terms Includes a new appendix discussing Brazilian environmental laws and regulations added to existing appendices outlining U.S., E.U., Chinese, Australian, and Indian environmental laws Fundamentals of Ecotoxicology: The Science of Pollution, Fifth Edition contains a broad overview of ecotoxicology and provides a basic understanding of the field. Designed as a textbook for use in introductory graduate or upper-level undergraduate courses in ecotoxicology, applied ecology, environmental pollution, and environmental science, it can also be used as a general reference for practicing environmental toxicologists.
A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.
Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists. - 25% brand new information, fully revised throughout - New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology - New color photomicrographs detailing specific toxicant-induced diseases in animals - Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels