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Immunobiology of Transfer Factor compiles research papers presented at the Fourth International Transfer Factor Workshop, held at the Given Institute of Pathobiology in Aspen, Colorado, on October 3-6, 1982. This book focuses on the immunologic effects of transfer factor, which are supported by in vitro and in vivo experiments that indicate immunologically specific interactions between transfer factor and antigens. The topics include the selective removal of transfer factor activity with antigen, antigen-specific suppressor factor in human leukocyte dialysates, and specific suppressor dialysates from mice. The kinetics of immune response and production of transfer factor in bovine, dialyzable leukocyte extracts in pulmonary diseases, and mechanisms of action of human transfer factor are also elaborated. This compilation is suitable for microbiologists, immunologists, and specialists researching on transfer factor.
Immune Regulators in Transfer Factor is a collection of papers presented at the Third International Symposium on Transfer Factor held on October 12-14, 1978 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors focus on immune regulators occurring in transfer factor, a dialyzable component of leukocyte lysates. The isolation and characterization of the immunologically active molecules, as well as tests for in vitro and in vivo, are described. This volume is organized into five sections encompassing 73 chapters and begins with an overview of animal models used in research on dialyzable leukocyte extracts, their modulation of suppressor activity, effects in mice, and activity and specificity of human and bovine transfer factor. The next section considers in vitro testing, touching on topics such as the quantification and biological assays of transfer factor; the specificity of transfer factor action on macrophage migration; and the effect of transfer factor therapy on antibody-dependent cytotoxic activity in humans. The reader is then introduced to the preparation, purification, and characterization of transfer factor, as well as clinical investigations ranging from phase I studies to randomized controlled trials. This book will be of interest to scientists and researchers in fields such as molecular medicine, biomedicine, microbiology, immunology, oncology, pathology, and immunotherapy.
In the second edition of this popular book, Dr. White takes readers on a tour of the human immune system, explores the nature of immune disorders from cancer to HIV and presents evidence that immune messengers called transfer factors can help the body beat a wide variety of diseases for which effective treatments are lacking. In language that is easy to follow, Dr. White explains how transfer factors help the body fight viruses (herpes, hepatitis C, HPV, HIV), mycobacteria (tuberculosis), cell-wall deficient bacteria (Lyme), cancers, autoimmune diseases and other conditions. Like vaccines but safer, transfer factors can be used to immunize the public against diseases before they spread. This book is an enjoyable read about a fascinating topic. As in the first edition, Dr. White blends science, history, medicine and politics with compelling story telling and wit. Whether you are a patient, doctor, health enthusiast or just a fan of good science writing, this is one to keep on your book shelf. Bound to be classic in the alternative medicine literature.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
To date, transfer factors hold promise as one of the most exciting discovery in immunology and disease prevention. As the 21st century unfolds, these small molecules represent an important key to human health and well-being. Transfer factors are material present in dialysable leukocyte extracts capable of transferring cell-mediated immunity to pathogens. Transfer factors from one immune donor can be introduced into a non-immune recipient, potentially delivering an improved ability to fight threats to the recipient’s health. Similar to vaccines, transfer factors are prophylactic when administered prior to exposure to a pathogen. This book is an overview of basic immunology and the concept of transfer factors derived from past and current scientific publications. In this book, the properties, mechanism of action, and clinical applications of transfer factors are described. Since their discovery, evidence suggests transfer factors play an important role as immune modulators in treating diseases associated with the defective function of cell-mediated immunity such as cancer, infectious diseases, etc. The MF Plus Super Transfer Factor is then introduced including its function, characteristics, course, mode of administration, and advantages. The conclusion compiles research papers of transfer factor from years 2009 to 2020. This book will interest researchers and scientists in fields such as immunology, molecular medicine, biomedicine, immunotherapy, pathology, microbiology, and oncology.
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research
Clinical Immunobiology, Volume 2 covers the advances in the field being made to apply bone marrow transplantation to the treatment of several diseases. This volume is divided into 11 chapters and begins with surveys of the clinical considerations of bone marrow transplantation. Considerable chapters are devoted to the application of this transplantation to the treatment of various diseases, including aplastic anemia, aregenerative pancytopenia, leukemia, uniformly fatal severe combined immunodeficiency diseases, and Wiskott-Aldrich syndrome. Other chapters examine the cellular engineering in the form of bone marrow and thymus transplantation. The remaining chapters consider the effects of exposure to excessive amounts of radiation or cytotoxic chemicals, as well as the hematopoietic failure based on malfunction of the complex process of normal hematological development and maintenance. This book will be of great value to clinical immunobiologists, practicing physicians, researchers, and medical and biology students.