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Paper, milk, clouds and white paint share a common property: they are opaque disordered media through which light scatters randomly rather than propagating in a straight path. For very thick and turbid media, indeed, light eventually propagates in a 'diffusive' way, i.e. similarly to how tea infuses through hot water. Frequently though, a material is neither perfectly opaque nor transparent and the simple diffusion model does not hold. In this work, we developed a novel optical-gating setup that allowed us to observe light transport in scattering media with sub-ps time resolution. An array of unexplored aspects of light propagation emerged from this spatio-temporal description, unveiling transport regimes that were previously inaccessibile due to the extreme time scales involved and the lack of analytical models.
Ground-based/terrestrial radar interferometry (GBRI) is a scientific topic of increasing interest in recent years. The GBRI is used in several field as remote sensing technique for monitoring natural environment (landslides, glacier, and mines) or infrastructures (bridges, towers). These sensors provide the displacement of targets by measuring the phase difference between sending and receiving radar signal. If the acquisition rate is enough the GBRI can provide the natural frequency, e.g. by calculating the Fourier transform of displacement. The research activity, presented in this work, concerns design and development of some advanced GBRI systems. These systems are related to the following issue: detection of displacement vector, Multiple Input Multiple Output (MIMO) and radars with 3D capability.
Malformations of cortical development (MCDs) result from a disruption in the process of the human brain cortex formation: currently, there are no pharmacological treatments for diffuse MCDs. Next-generation sequencing has accelerated the identification of MCDs causing genes: in some cases, functional studies are needed to clarify the role of genetic variants. The aim of this PhD project has been to apply a multidisciplinary approach to identify causative mutations in patients with MCDs, validate the pathogenic role of the identified mutations, and assess the effectiveness of novel in vitro treatment for mTOR pathway related MCDs.
In this work the central area of Corsica island was studied in order to reconstruct the tectono-metamorphic history of the continental and oceanic high pressure units that occupy the structurally deeper levels of the tectonic stacking of Alpine Corsica and their stratigraphic and structural relationship with the European margin (Hercynian Corsica). The study includes the geological mapping, the mesoscale and microscale structural analysis, the acquisition of chemical analyzes and micromaps with the microprobe, thermobarometric estimation through specific methodologies for metapelites, U-Th-Pb dating of zircons and allanites. The results obtained allows to reconstruct the geodynamic model of this sector of the Alpine belt from the Permian to the Burdigalian.
One of the most important tools to investigate the chemical history of our Galaxy and our own Solar System is to measure the isotopic fractionation of chemical elements. In the present study new astronomical observations devoted to the study of hydrogen and nitrogen fractionation (D/H and 14N/15N ratios) of molecules, towards massive star-forming regions in different evolutionary phases, have been presented. Moreover, a new detailed theoretical study of carbon fractionation, 12C/13C ratios, has been done. One of the main results was the confirmation that the 14N/15N ratio increases with the galactocentric distance, as predicted by stellar nucleosynthesis Galactic chemical evolution models. This work gives new important inputs on the understanding of local chemical processes that favor the production of molecules with different isotopes in star-forming regions.
Most cameras are inherently designed to mimic what is seen by the human eye: they have three channels of RGB and can achieve up to around 30 frames per second (FPS). However, some cameras are designed to capture other modalities: some may have the ability to capture spectra from near UV to near IR rather than RGB, polarimetry, different times of light travel, etc. Such modalities are as yet unknown, but they can also collect robust data of the scene they are capturing. This book will focus on the emerging computer vision techniques known as computational imaging. These include capturing, processing and analyzing such modalities for various applications of scene understanding.
A comprehensive and up-to-date textbook and reference for computational imaging, which combines vision, graphics, signal processing, and optics. Computational imaging involves the joint design of imaging hardware and computer algorithms to create novel imaging systems with unprecedented capabilities. In recent years such capabilities include cameras that operate at a trillion frames per second, microscopes that can see small viruses long thought to be optically irresolvable, and telescopes that capture images of black holes. This text offers a comprehensive and up-to-date introduction to this rapidly growing field, a convergence of vision, graphics, signal processing, and optics. It can be used as an instructional resource for computer imaging courses and as a reference for professionals. It covers the fundamentals of the field, current research and applications, and light transport techniques. The text first presents an imaging toolkit, including optics, image sensors, and illumination, and a computational toolkit, introducing modeling, mathematical tools, model-based inversion, data-driven inversion techniques, and hybrid inversion techniques. It then examines different modalities of light, focusing on the plenoptic function, which describes degrees of freedom of a light ray. Finally, the text outlines light transport techniques, describing imaging systems that obtain micron-scale 3D shape or optimize for noise-free imaging, optical computing, and non-line-of-sight imaging. Throughout, it discusses the use of computational imaging methods in a range of application areas, including smart phone photography, autonomous driving, and medical imaging. End-of-chapter exercises help put the material in context.
This book describes the application of ultrafast laser science and technology in materials and processing relevant to industry today, including ultrafast laser ablation where fundamental studies have led to the development of the world's first femtosecond photomask repair tool. Semiconductor manufacturing companies worldwide use the tool to repair photomask defects, saving hundreds of millions in production costs. The most up-to-date ultrafast laser technologies are described and methods to generate high harmonics for photoelectron spectroscopy of industrially important materials are covered, with an emphasis on practical laboratory implementation. Basic device physics merged with photoemission studies from single- and polycrystalline materials are described. Extensions to new methods for extracting key device properties of metal-oxide-semiconductor structures, including band offsets, effective work functions, semiconductor band bending and defect-related charging in a number of technologically important gate oxides are detailed. Polycrystalline photovoltaic materials and heterostructures as well as organic light emitting materials are covered. This book describes both the history, and most recent applications of ultrafast laser science to industrially relevant materials, processes and devices.
The book "Fingerprints in the optical and transport properties of quantum dots" provides novel and efficient methods for the calculation and investigating of the optical and transport properties of quantum dot systems. This book is divided into two sections. In section 1 includes ten chapters where novel optical properties are discussed. In section 2 involve eight chapters that investigate and model the most important effects of transport and electronics properties of quantum dot systems This is a collaborative book sharing and providing fundamental research such as the one conducted in Physics, Chemistry, Material Science, with a base text that could serve as a reference in research by presenting up-to-date research work on the field of quantum dot systems.
During the past two decades, there has been an increasing appreciation of the significant value that lifetime-based techniques can add to biomedical studies and applications of fluorescence. Bringing together perspectives of different research communities, Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics explores the remarkable advances in time-resolved fluorescence techniques and their role in a wide range of biological and clinical applications. Broadly accessible, the book captures the state-of-the-art of fluorescence lifetime metrology and imaging and provides current perspectives on their applications to biomedical studies of intact tissues and medical diagnosis. The text introduces these techniques within the wider context of fluorescence spectroscopy and describes basic principles underlying current instrumentation for fluorescence lifetime imaging and metrology (FLIM). It also covers the wide range of methods, including single channel (point) spectroscopy, fluorescence lifetime imaging microscopy, and single- and multi-photon excitation. Edited by pioneers in this field, with contributions from leading experts, the book includes an overview of complementary techniques that help researchers beginning FLIM research. It offers a comprehensive treatment of fundamental principles, instrumentation, analytical methods, and applications. It also provides an overview of the label-free contrast available from lifetime measurements of tissue autofluorescence and the prospects for exploiting this for clinical applications and biomedical research including drug discovery.