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This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
This book introduces readers to cybersecurity and its impact on the realization of the Industry 4.0 vision. It covers the technological foundations of cybersecurity within the scope of the Industry 4.0 landscape and details the existing cybersecurity threats faced by Industry 4.0, as well as state-of-the-art solutions with regard to both academic research and practical implementations. Industry 4.0 and its associated technologies, such as the Industrial Internet of Things and cloud-based design and manufacturing systems are examined, along with their disruptive innovations. Further, the book analyzes how these phenomena capitalize on the economies of scale provided by the Internet. The book offers a valuable resource for practicing engineers and decision makers in industry, as well as researchers in the design and manufacturing communities and all those interested in Industry 4.0 and cybersecurity.
Atrial Fibrillation from an Engineering Perspective provides an up-to-date overview of techniques developed for acquisition, modeling, and analysis of noninvasive, bioelectrical signals reflecting this common arrhythmia. Special emphasis is put on emerging technologies for monitoring of atrial fibrillation in connection with ischemic stroke, interventional ablation procedures, and pharmacological treatment, applications which all depend on the availability of techniques for detecting and characterizing episodes of paroxysmal atrial fibrillation. Detectors exploring both rhythm and morphology are described, as well as detectors confined to rhythm and better suited for low power implementation. A wide variety of approaches to modeling and characterization of atrial activity are described, emanating from a statistical and deterministic starting points. This book is suitable for graduate students, researchers, and engineers who want a comprehensive treatise of atrial fibrillation from an engineering perspective. It may be used for self-study, as a supplement to courses in signal processing, or as a modern monograph by researchers in the field of atrial fibrillation.
The Director of this study, Abraham Kagan, has comprehensively summarized the design and main finndings of the study in this book. The Honolulu Heart Program compared and contrasted ethnic Japanese men living in different cultural environments--Honolulu and mainland Japan--assessed their relative risk factors. The study supported many of the existing views on risk factors but also showed suprising trends. One of the trends shows moderate alcohol consumption is a preventative factor. In recent years the risk factors for cardiovascular diseases have become common knowledge. The recently completed Honolulu Heart Program is the largest targeted study to evaluate scientifically such risk factors.
The definitive text for students of digital forensics, as well as professionals looking to deepen their understanding of an increasingly critical field Written by faculty members and associates of the world-renowned Norwegian Information Security Laboratory (NisLab) at the Norwegian University of Science and Technology (NTNU), this textbook takes a scientific approach to digital forensics ideally suited for university courses in digital forensics and information security. Each chapter was written by an accomplished expert in his or her field, many of them with extensive experience in law enforcement and industry. The author team comprises experts in digital forensics, cybercrime law, information security and related areas. Digital forensics is a key competency in meeting the growing risks of cybercrime, as well as for criminal investigation generally. Considering the astonishing pace at which new information technology – and new ways of exploiting information technology – is brought on line, researchers and practitioners regularly face new technical challenges, forcing them to continuously upgrade their investigatory skills. Designed to prepare the next generation to rise to those challenges, the material contained in Digital Forensics has been tested and refined by use in both graduate and undergraduate programs and subjected to formal evaluations for more than ten years. Encompasses all aspects of the field, including methodological, scientific, technical and legal matters Based on the latest research, it provides novel insights for students, including an informed look at the future of digital forensics Includes test questions from actual exam sets, multiple choice questions suitable for online use and numerous visuals, illustrations and case example images Features real-word examples and scenarios, including court cases and technical problems, as well as a rich library of academic references and references to online media Digital Forensics is an excellent introductory text for programs in computer science and computer engineering and for master degree programs in military and police education. It is also a valuable reference for legal practitioners, police officers, investigators, and forensic practitioners seeking to gain a deeper understanding of digital forensics and cybercrime.
In recent years, social innovation has experienced a steep career. Numerous national governments and large organisations like the OECD, the European Commission and UNESCO have adopted the term. Social innovation basically means that people adopt new social practices in order to meet social needs in a different or more effective way. Prominent examples of the past are the Red Cross and the social welfare state or, at present, the internet 2.0 transforming our communication and cooperation schemes, requiring new management concepts, even empowering social revolutions. The traditional concept of innovation as successful new technological products needs fundamental rethinking in a society marked by knowledge and services, leading to a new and enriched paradigm of innovation. There is multiple evidence that social innovation will become of growing importance not only concerning social integration, equal opportunities and dealing with the greenhouse effects but also with regard to preserving and expanding the innovative capacity of companies and societies. While political authorities stress the social facets of social innovation, this book also encompasses its societal and systemic dimensions, collecting the scientific expertise of renowned experts and scholars from all over the world. Based on the contributions of the first world-wide science convention on social innovation from September 2011 in Vienna, the book provides an overview of scientific approaches to this still relatively new field. Forewords by Agnès HUBERT (Member of the Bureau of European Policy Advisers (BEPA) of the European Commission) and Antonella Noya (Senior Policy Analyst at OECD, manager of the OECD LEED Forum on Social Innovations)
This book introduces the latest optical coherence tomography (OCT) imaging and computerized automatic image analysis techniques, and their applications in the diagnosis and treatment of retinal diseases. Discussing the basic principles and the clinical applications of OCT imaging, OCT image preprocessing, as well as the automatic detection and quantitative analysis of retinal anatomy and pathology, it includes a wealth of clinical OCT images, and state-of-the-art research that applies novel image processing, pattern recognition and machine learning methods to real clinical data. It is a valuable resource for researchers in both medical image processing and ophthalmic imaging.
Project Society After Money is an interdisciplinary project between commons theory, evolutionary political economy, media studies and sociology, that enter into a dialogue with one another in order to look at their specific theories and criticisms of money. Conceived as the beginning of a necessary interdisciplinary dialogue, the possibilities of post-monetary forms of organization and production are taken into account and examined. On one hand there is a lot of talk about 'digital revolution', 'mediatized society', 'networks', 'Industry 4.0'. On the other hand the present is described in terms of crisis: 'financial crisis', 'economic crisis', 'planetary boundaries'. At once there is the description of a media-technological change along with massive social and ecological disruptions. Society After Money is based on the premise that there might be a conflict between digital media/digital technology and the medium of money – and perhaps new digital possibilities that allow alternative forms of economy. It criticizes what is normally seen as self-evident and natural, namely that social coordination has to be done by the medium of money. We're left with a highly innovative collection of contributions that initiates a broader social discourse on the role of money in the global society of the 21st century.
What factors determine healthy behavior? Health Psychology: Well-Being in a Diverse World answers this question by introducing and regularly applying research to stress, coping, interventions and health behaviors in today’s world. Speaking directly to students, Regan A. R. Gurung’s conversational voice guides learners through the key determinants of behavior, such as family, environment, ethnicity, and religion. Each chapter delves into the biological foundations of health, presents interdisciplinary case studies, and integrates personality and social psychological theories, fostering a comprehensive grasp of the subject. Continually asking readers to think further, to synthesize, to analyze, and to apply to improve their own health outcomes as they learn, Gurung empowers students through connections to personal experience. The Fifth Edition offers contemporary reference updates, an expanded focus on intersectional topics across cultures, test yourself practice, and much more. This title is accompanied by a complete teaching and learning package. Contact your Sage representative to request a demo. Learning Platform / Courseware Sage Vantage is an intuitive learning platform that integrates quality Sage textbook content with assignable multimedia activities and auto-graded assessments to drive student engagement and ensure accountability. Unparalleled in its ease of use and built for dynamic teaching and learning, Vantage offers customizable LMS integration and best-in-class support. It′s a learning platform you, and your students, will actually love. Learn more. LMS Cartridge: Import this title’s instructor resources into your school’s learning management system (LMS) and save time. Don’t use an LMS? You can still access all of the same online resources for this title via the password-protected Instructor Resource Site. Learn more.