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Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide delivers a concise review of our current understanding of disease pathogenesis and provides current evidence in the medical literature regarding its diagnosis and management. Each chapter includes key points and a summary aiming to update clinicians about various issues concerning the diagnosis and management of IPF. In addition to outlining the current state of knowledge, each chapter also provides a summary of ongoing research and identifies the needs for future research in the field. Idiopathic Pulmonary Fibrosis: A Comprehensive Clinical Guide is an important new text that provides its readers with a better understanding of the pathobiology and natural history of IPF as it continues to evolve.
Idiopathic pulmonary fibrosis (IPF) is a steadily progressive and ultimately fatal disease of unknown origin. Recent years have seen advances in our understanding of IPF and a number of guidelines have been published. But many questions remain unanswered, particularly surrounding probable versus definite IPF. This Monograph aims to discuss the latest achievements in IPF, and covers key diagnostic issues, staging of the disease, complications and comorbidities, treatment, unmet patient needs and perspectives for the future. This book will be of interest to all clinicians and researchers in this area.
Designed with the practicing clinician in mind, Idiopathic Pulmonary Fibrosis provides a succinct, easy-to-digest overview of this challenging condition in which the cause of thickening lung tissue is unknown. This concise resource by Drs. Kevin K. Brown and Jeff Swigris provides essential information for the physician who sees pulmonary fibrosis patients, including epidemiology, genetics and biomarkers, pathology, diagnosis, disease monitoring, and therapeutics intended to improve the patient's lifespan and quality of life. - Covers the process of making the diagnosis of idiopathic pulmonary fibrosis, as well as IPF look-alikes: uncharacterized PF, CTD-ILD, and cHP. - Details today's available therapeutics, including Rx, rehabilitation, O2, Tx, and treating comorbidities: OSA, GERD, and PH. - Consolidates today's available information on this timely topic into one convenient resource.
This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.
This book is a comprehensive and easy-to-read guide to pulmonary imaging. Medical Imaging is one of the cornerstones of modern medicine, and nowhere is this more apparent than pulmonary disease. We have come a long way from the days of chest radiography, though the chest radiograph still remains the single most common imaging test ordered worldwide. Pulmonary disease is now routinely evaluated with ultra-modern computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) scanners, while ultrasonography plays a limited role in critical care and pleural/chest wall diseases. Rapid advancements in the sub-specialty of chest imaging and an exponential increase in the knowledge of pulmonary disease have led to an increasing demand for a comprehensive yet easily digestible handbook of pulmonary imaging, which prepackages knowledge in a form that can be easily understood and readily visualized with high-quality representative images. This book answers that need by providing the most important, relevant medical knowledge needed to handle pulmonary cases. It is divided into two sections, neoplastic disease and non-neoplastic disease. Chapters detail essential information about each disease, including presentation and the different modalities used to accurately diagnose and/or plan treatment. Major topics that are covered include bronchogenic carcinoma and other lung tumors, COPD, ILD, developmental lung disorders, pulmonary hypertension, and pulmonary infections. Each chapter includes extensive radiographic images to give a complete perspective on how these diseases present. Readers can easily see what the radiology of a particular disease entity looks like, what would be the differential diagnoses for a particular imaging abnormality, and compare the bullet review points associated with an image to their particular case. This is an ideal guide for general and thoracic radiologists, pulmonary, sleep medicine, and critical care specialists, thoracic surgeons, as well as residents and all clinicians who treat patients with pulmonary disease.
People age 65 and older are the fastest growing segment of the U.S. population. In the 2010 census 16% of the population, 50 million people, were age 65 and older. That number is projected to increase to 66 million by the year 2050. Life expectancy has also increased, with recent CDC reports indicating life expectancy at 77.9 years. Age-adjusted death rates have decreased significantly with the largest changes occurring in older patients. Despite these trends, the 10 leading causes of death include several pulmonary etiologies including lung cancer, chronic respiratory diseases, influenza and pneumonia. Aging and Lung Disease: A Clinical Guide is devoted to understanding the impact of respiratory diseases in older patients. It includes reviews of physiology of the aging lung, allergy and immunology of the aging, as well as sleep changes over the life cycle. There are also comprehensive reviews on specific disease topics including chronic obstructive lung disease, lung cancer, atypical mycobacteria, interstitial lung disease, pulmonary hypertension, pulmonary embolism, obstructive sleep apnea, sleep disorders in older patients. Two chapters focus on unique issues in older patients; HIV and lung transplant. Included also are important chapters on assessing functional and cognitive status and end-of-life issues in older patients with lung disease. In addition to outlining the current state of knowledge, each chapter focuses on special considerations when caring for older patients. Of particular interest to pulmonologists, internists, and gerontologists, other readers, such as pulmonary and geriatric nurse practitioners, as well as clinical researchers interested in both pulmonary and aging issues, will find Aging and Lung Disease: A Clinical Guide to be a vital resource for improving their care of older patients with lung disorders.
This Monograph provides expert clinical guidance on these difficult diseases, which will be helpful to both respiratory and nonrespiratory physicians alike. The initial chapters consider diagnostic issues, pulmonary function tests and techniques that are currently in development. The book then goes on to cover a variety of pulmonary manifestations of very different disease entities, such as connective tissue diseases, systemic vasculitis and much more.
With contributions by numerous experts
The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.