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Complete reference on hypoxic pulmonary vasoconstriction and hypoxia-mediated pulmonary hypertension. Can be utilized by the physician-scientist and researcher in the laboratory as both a technical manual and reference. Designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure.
Nunn's Applied Respiratory Physiology.
This book exemplifies the new problem-orientated approach to teaching anaesthesia. It comprises four sections that correspond closely with the four-year training programme set out by the American Board of Anesthesiology for candidates studying for the Diploma in Anesthesiology and with the new FRCA primary examination. The first three sections provide an integrated core text covering material that every trainee needs to know and understand, while the fourth section is a multi-author review of more specialized topics. Contributions are drawn from experts in the UK, Europe, the USA and Australasia, so presenting the best of current opinion and practice worldwide. Its highly illustrated presentation provides readers with a source of information on key topics that is concise and can readily be assimilated.
Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.
Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are a hotly debated topic in physiology. This book highlights the latest discoveries on the role of K+ channels in the heart and blood vessels in normal physiology and a variety of disease states.
Covers all of the equations that candidates need to understand and be able to apply when sitting postgraduate anaesthetic examinations.
The heart and lung are intricately linked. When the heart is affected by disease, the lungs will often show some related pathological or clinical conditions and vice versa. Pulmonary heart disease is by definition a condition when the lungs cause the heart to fail. The left ventricle in combination with the other structures in the “left heart” pumps blood throughout the body. The right ventricle (and structures of the “right heart”) pumps blood to the lungs where it is oxygenated and returned to the left heart for distribution. In normal circumstances, the right heart pumps blood into the lungs without any resistance. The lungs usually have minimal pressure and the right heart easily pumps blood through. However when there is lung disease present, like emphysema, chronic obstructive lung disease (COPD) or pulmonary hypertension- the small blood vessels become very stiff and rigid. The right ventricle is no longer able to push blood into the lungs and eventually fails. This is known as pulmonary heart disease. Pulmonary heart disease is also known as right heart failure or cor pulmonale. The chief cause of right heart failure is the increase in blood pressure in the lungs (pulmonary artery).
The critical care unit manages patients with a vast range of disease and injuries affecting every organ system. The unit can initially be a daunting environment, with complex monitoring equipment producing large volumes of clinical data. Core Topics in Critical Care Medicine is a practical, comprehensive, introductory-level text for any clinician in their first few months in the critical care unit. It guides clinicians in both the initial assessment and the clinical management of all CCU patients, demystifying the critical care unit and providing key knowledge in a concise and accessible manner. The full spectrum of disorders likely to be encountered in critical care are discussed, with additional chapters on transfer and admission, imaging in the CCU, structure and organisation of the unit, and ethical and legal issues. Written by Critical Care experts, Core Topics in Critical Care Medicine provides comprehensive, concise and easily accessible information for all trainees.
We have all been hypoxic. Fetal tolerance for intrauterine hypoxia arises from evolutionarily conserved physiological mechanisms, the antecedents of which can be learned from diving mammals or species at high altitudes. Understanding fetal hypoxia leads to understanding the huge physiological shifts of neonatal transition and the dangers of perinatal hypoxia. This comprehensive volume of topical review articles by expert authors addresses the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit, as well as the classification, diagnosis, and clinical management of hypoxic respiratory failure and persistent pulmonary hypertension in the term neonate. The goal of Hypoxic Respiratory Failure in the Newborn is to connect our understanding of hypoxia from animals in extreme environments, with how the human fetus handles its hypoxic environment; and why the human newborn suddenly cannot. The book will educate health care professionals on how to care for newborns with hypoxic respiratory failure, including the use of up-to-date diagnostic tools and therapies. It also highlights areas of controversy and ongoing research in hypoxic respiratory failure and pulmonary hypertension of the newborn, including challenging case studies. Key Features Explores evolutionary context and comparative physiology of hypoxia tolerance in the fetus and neonate, from basic research to clinical scenarios Provides guidance to trainees, physicians, and allied health professionals engaged in NICU care; pediatricians, cardiologists, pulmonologists, anesthesiologists, neonatologists, and physiologists to effectively manage infants in hypoxic respiratory failure Includes case scenarios emphasizing current diagnostic and therapeutic controversies and algorithmic approaches to decipher difficult clinical cases
Ideal for clinicians at all levels of experience—from the resident to the subspecialist—Cohen's Comprehensive Thoracic Anesthesia compiles the many recent advances in thoracic anesthesiology into one convenient, easy-to-use reference. Concise, clinically focused chapters written by international authorities in the field cover all facets of anesthesia practice for thoracic procedures, logically organized by preoperative, intraoperative, and postoperative considerations. - Discusses new devices for lung isolation, new lung protection protocols, new information on post-operative complications, and new drugs for modulating pulmonary circulation. - Covers 20 key procedures including tracheal resection, esophagectomy, mediastinoscopy, mediastinal mass, SVC syndrome, and more. - Describes complex surgeries related to the lungs, pleura, diaphragm, and esophagus. - Provides case studies and clinical vignettes to illustrate and support case management decisions. - Offers highly practical guidance for quick reference from editor Dr. Edmond Cohen and a team of expert contributing authors from around the world. - Features extensive illustrations throughout, including clinical photos and drawings, radiographic images, device images, charts, and graphs.