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My personal involvement with the problem of hydrophobic interactions (HI) began about ten years ago. At that time I was asked to write a review article on the properties of aqueous solutions of nonpolar solutes. While surveying the literature on this subject I found numerous discussions of the concept of HI. My interest in these interactions increased especially after reading the now classical review of W. Kauzmann (1959), in which the importance of the HI to biochemical processes is stressed. Yet, in spite of having read quite extensively on the various aspects of the subject, I acquired only a very vague idea of what people actually had in mind when referring to HI. In fact, it became quite clear that the term HI was applied by different authors to describe and interpret quite different phenomena occurring in aqueous solutions. Thus, even the most fundamental question of the very definition of the concept of HI remained unanswered. But other questions followed, e. g. : Are HI really a well established experimental fact? Is there any relation between HI and the peculiar properties of water? Is the phenomenon really unique to aqueous solutions? Finally, perhaps the most crucial question I sought to answer was whether or not there exists hard evidence that HI are really important -as often claimed-in biological processes.
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Cognitive disorders are a growing concern, affecting individuals across the age spectrum and society. These disorders can profoundly disrupt daily life, and their timely diagnosis is crucial for effective intervention and care. As the prevalence of cognitive disorders continues to rise, the need for precise and early diagnosis has never been more pressing. Intelligent Solutions for Cognitive Disorders is a research-based book which delves into the intersection of medical science and technology, exploring the latest advancements in cognitive disorder diagnosis and treatment. This book assembles a multidisciplinary team of experts, including researchers, clinicians, and technologists, to address this challenge head-on. This book commences with an in-depth introduction to cognitive disorders, providing a solid foundation for readers of all backgrounds. It then navigates the role of intelligent systems in cognitive healthcare, unveiling the potential of artificial intelligence, machine learning, and deep learning techniques. The book highlights how these intelligent systems can enable the early and accurate detection of cognitive disorders, a pivotal factor in improving patients' quality of life. This book is an invaluable resource for technologists, researchers, linguists, data scientists, healthcare practitioners, medical professionals, and students seeking a comprehensive understanding of cognitive disorders and the role of intelligent technologies in their diagnosis and care.