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This book reviews how we can record the human brain's response to sounds, and how we can use these recordings to assess hearing. These recordings are used in many different clinical situations--the identification of hearing impairment in newborn infants, the detection of tumors on the auditory nerve, the diagnosis of multiple sclerosis. As well they are used to investigate how the brain is able to hear--how we can attend to particular conversations at a cocktail party and ignore others, how we learn to understand the language we are exposed to, why we have difficulty hearing when we grow old. This book is written by a single author with wide experience in all aspects of these recordings. The content is complete in terms of the essentials. The style is clear; equations are absent and figures are multiple. The intent of the book is to make learning enjoyable and meaningful. Allusions are made to fields beyond the ear, and the clinical importance of the phenomena is always considered.
From August 25 - 28, 1978 a conference on averaged evoked po tentials was held at Konstanz, West Germany. Research on human evoked potentials has progressed rapidly in the past decade, and a series of international conferences have served to maintain com munication between active workers in the field. Among the organiza tions that have a tradition of supporting such mUlti-national com munication are the North Atlantic Treaty Organization Scientific Affairs Division, the u.s. Office of Naval Research and the German Research Society (Deutsche Forschungsgemeinschaft). We have been fortunate to have the support of all three. In the early stages of planning, a committee was formed composed of Professors Rudolph Cohen (Konstanz), Otto Creutzfeldt (Goettingen), John Desmedt (Brussels), A.M. Halliday (London), Anthony Remond (Paris) and Herbert Vaughan (New York). A call for papers was circulated as widely as possible, and this committee carried out the difficult task of selecting a limited number of participants from a large number of excellent abstracts. At the same time Professor Cohen of the University of Konstanz was generous enough to shoulder the task of playing host to the conference. His thoughtful arrangements contributed enormously to the comfort of the participants. He and his colleagues also engi neered an ideal ambience for sharing of ideas and observations, while the University of Konstanz generously provided audio-visual support.
Written by experts with extensive clinical and scientific experience, this comprehensive textbook presents the state of the art in auditory evoked potentials. Opening chapters explain the nature of electrical fields that generate surface recorded potentials, summarize the imaging modalities that complement evoked potential studies, and review acoustics and instrumentation. Major sections examine the anatomy and physiology of the auditory periphery, brainstem, and cortex and the principles and clinical applications of auditory, myogenic, visual, somatosensory, and vestibular evoked potentials. Chapters present hands-on laboratory exercises and clinical case studies. A full-color insert includes 3D images from multi-channel evoked potentials and functional imaging.
This volume is the second in "The Downstate Series of Research in Psychiatry." It is aseries devoted to the presentation of sig nificant research with relevance for both clinicians and researchers in the multiple subfields of psychiatry. This book focuses on the interactions between psychic phenomena and physical processes as studied by evoked brain potentials. It presents material concerned with physiological and psychological unifying processes, as weIl as research concerning technology and methods of obtaining meaningful measurements. As such it is representative of biological psychiatry at its best. Thus, it represents another step in new directions in psychiatric research but not an unanticipated direction. Scientific investigation into the human psyche took an unex pected turn when Sigmund Freud in the last part of the 19th Century turned his attention from neurological concerns to those of psychol ogy. His first attempts at explanations as noted in the "project," included a heavy emphasis on the biological substrate of behavior.
Transcranial stimulation comprises an important set of techniques for investigating brain function, some of which promise to treat diseases. This book provides a review of the scientific and technical background required to understand transcranial stimulation, for neuroscientists, neurologists, and psychiatrists.
An essential guide to designing, conducting, and analyzing event-related potential (ERP) experiments, completely updated for this edition. The event-related potential (ERP) technique, in which neural responses to specific events are extracted from the EEG, provides a powerful noninvasive tool for exploring the human brain. This volume describes practical methods for ERP research along with the underlying theoretical rationale. It offers researchers and students an essential guide to designing, conducting, and analyzing ERP experiments. This second edition has been completely updated, with additional material, new chapters, and more accessible explanations. Freely available supplementary material, including several online-only chapters, offer expanded or advanced treatment of selected topics. The first half of the book presents essential background information, describing the origins of ERPs, the nature of ERP components, and the design of ERP experiments. The second half of the book offers a detailed treatment of the main steps involved in conducting ERP experiments, covering such topics as recording the EEG, filtering the EEG and ERP waveforms, and quantifying amplitudes and latencies. Throughout, the emphasis is on rigorous experimental design and relatively simple analyses. New material in the second edition includes entire chapters devoted to components, artifacts, measuring amplitudes and latencies, and statistical analysis; updated coverage of recording technologies; concrete examples of experimental design; and many more figures. Online chapters cover such topics as overlap, localization, writing and reviewing ERP papers, and setting up and running an ERP lab.
Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.