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The overall purpose of this study is to investigate the role that environmental-level magnetic fields may play as an exogenous factor in the etiology of human breast cancer. There are several important observations that have been made during the research conducted in this reporting period. We have further characterized the EMF blocking effect on the oncostatic action of melatonin and tamoxifen on human breast cancer cell growth in vitro. Field dose studies suggest that this blocking effect is observed at field strengths of up to 1Gauss (1000mG, 100uTesla) with a lower threshold between 6 - 12mG. Studies investigating the critical duration of exposure suggest that at least two days of continuous field exposure is required; this corresponds to one cell-cycle period. In biologically-based studies it was shown that melatonin concentration in the media itself is not influenced by a 2 vs 12mG magnetic field. The original melatonin findings presented in our proposal recently have been independently replicated at the EPA.
The link between the pineal gland and cancer is a rapidly emerging research field due to promising experimental and clinical trials with melatonin. The pineal gland acts as a transducer of environmental light to regulate rhythmic processes, including reproductive function in seasonally breeding animals and the entrainment of circadian rhythms, such as the sleep-wake cycle, in man. This book elucidates the physiological significance of the pineal gland and surveys phenomena and mechanisms of pineal - tumor interaction at the neuroendocrine, neuroimmune, neural, and molecular levels. Yet unidentified low-molecular-weight pineal substances with tumor-inhibiting capacity, a possible involvement of melatonin in electromagnetic field effects on cancer, and the oncotherapeutic potential of melatonin are also addressed. The encouraging results should incite further research to elucidate the exact nature of the link between the pineal gland and cancer for the benefit of patients.
Can the electric and magnetic fields (EMF) to which people are routinely exposed cause health effects? This volume assesses the data and draws conclusions about the consequences of human exposure to EMF. The committee examines what is known about three kinds of health effects associated with EMF: cancer, primarily childhood leukemia; reproduction and development; and neurobiological effects. This book provides a detailed discussion of hazard identification, dose-response assessment, exposure assessment, and risk characterization for each. Possible Health Effects of Exposure to Residential Electric and Magnetic Fields also discusses the tools available to measure exposure, common types of exposures, and what is known about the effects of exposure. The committee looks at correlations between EMF exposure and carcinogenesis, mutagenesis, neurobehavioral effects, reproductive and developmental effects, effects on melatonin and other neurochemicals, and effects on bone healing and stimulated cell growth.
Earth’s endemic life exists on an active planet, and its physical characteristics shape its development by affecting it in many ways. The planet’s magnetic field plays its part in that scenario. In this new book, the author concentrates on this little-understood aspect of terrestrial life’s existence. In an all-pervasive way, Earth’s natural magnetism imparts a pulse to the life forms that exist on the planet. From the very simplest to the most complex, organisms cannot ignore their natural magnetic environment. A lot of recent research into this phenomenon has been collated and reviewed by the author. In this book, he appraises the evidence from that research in a scientific yet interesting manner.
People are immersed in electromagnetic fields from such sources as power lines, domestic appliances, mobile phones, and even electrical storms. All living beings sense electric fields, but the physical origins of the phenomenon are still unclear. Magnetobiology considers the effects of electromagnetic fields on living organisms. It provides a comprehensive review of relevant experimental data and theoretical concepts, and discusses all major modern hypotheses on the physical nature of magnetobiological effects. It also highlights some problems that have yet to be solved and points out new avenues for research. Why do some people feel unwell during a lightning storm? Why is there a correlation between the level of electromagnetic background and the incidence of cancer? Why do so many medical centers use electromagnetic exposures to treat a wide variety of disorders in humans? The international scientific community is extremely interested in a theory of magnetobiology and the answers to these and other questions, as evidenced by the growing number of research associations in the United States, Europe, and other parts of the world. The World Health Organization (WHO) has named electromagnetic contamination in occupational and residential areas as a stress factor for human beings. This book stands out among recent texts on magnetobiology because it draws on a strong foundation of empirical and theoretical evidence to explain the various effects of magnetic fields on the human body. It contains the first comprehensive collection of experimental data bearing physical information, frequency and amplitude/power spectra, and original research data on how electromagnetic fields interfere with ions and molecules inside the proteins of living organisms. - Introduction is written so that it will be understandable to a wide scientific community regardless of their specialisation - First comprehensive collection of experimental data bearing physical information, frequency and amplitude/power spectra - Original theoretical research data on the interference of ions and molecules inside proteins - Appendix covers physical questions most relevant for magnetobiology. In particular there is an original exposition of the magnetic resonance basic principles
This book, a selection of the papers presented at the 2nd World Congress for Electricity and Magnetism, provides state-of-the-art information on applications of electricity and electromagnetic fields on living organisms, especially man.