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How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges
This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.
Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases
Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews: "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer’s disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspired Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Historically, mental health clinical research has taken inadequate account of psychosocial disorders experienced by those who identify as sexual and gender minorities, however, researchers have recently begun developing and adapting evidence-based mental health treatment approaches for use with these groups. Handbook of Evidence-Based Mental Health Practice with Sexual and Gender Minorities offers a comprehensive array of evidence-based approaches for treating sexual and gender minority clients' mental health concerns. The interventions detailed here span a diverse spectrum of populations, including sexual and gender minority youth, transgender populations, same-sex couples, sexual minority parents, and bisexual individuals. Chapters also address numerous mental and behavioral health problems, including anxiety disorders, depression, substance abuse, trauma, body image disturbance, and sexual health. In addition to an overview of the research evidence supporting each clinical presentation and approach, chapters contain practical how-to guidance for therapists to use in their clinical practice. This book reflects a true integration of the best of sexual and gender minority research and the best of evidence-based practice research, presented by the leading experts in the field. As such it is essential reading for mental health professionals who work with these groups, as well as trainees in social work, counseling, and clinical psychology.
Sexuality and Gender Now uses a psychoanalytic approach to arrive at a more informed view of the experience and relationships of those whose sexuality and gender may not align with the heterosexual "norm". This book confronts the heteronormative bias dominant in psychoanalysis, using a combination of theoretical and clinical material, offering an important training tool as well as being relevant for practicing clinicians. The contributors address the shift clinicians must make not only to support their patients in a more informed and non-prejudicial way, but also to recognise their own need for support in developing their clinical thinking. They challenge assumptions, deconstruct theoretical ideas, extend psychoanalytic concepts, and, importantly, show how clinicians can attend to their pre-conscious assumptions. They also explore the issue of erotic transference and countertransference, which, if unaddressed, can limit the possibilities for supporting patients more fully to explore their sexuality and gender. Theories of psychosexuality have tended to become split off from the main field of psychoanalytic thought and practice or read from an assumed moral high ground of heteronormativity. The book specifically addresses this bias and introduces new ways of using psychoanalytic ideas. The contributors advocate a wider and more flexible attitude to sexuality in general, which can illuminate an understanding of all sexualities, including heterosexuality. Sexuality and Gender Now will be essential reading for professionals and students of psychoanalysis who want to broaden their understanding of sexuality and gender in their clinical practice beyond heteronormative assumptions.
"This timely history tells the story of how 'gender' was invented in American medicine. The concept of gender shifted from a pragmatic tool in the sex assignment of children with intersex traits in the 1950s to an essential category in clinics for transgender patients in the 1960s, to a feature of feminist debates about the sex/gender binary in the 1970s, to the word we know today. Our current idea of gender might not map exactly onto these earlier formulations, but we still live with the legacy of this genealogy. Sandra Eder reveals that there was-without a doubt- something new, transformative, and enduring about the concept of gender that developed through clinical practices at pediatric endocrinology clinics. The history of gender laid out in this book shows that these ideas held no single, unified meaning-neither within the clinic nor outside it-and that 'gender' was shaped by the behaviors and needs of those who used and adapted it. This is not a neat and tidy story about the introduction of a liberating concept. Nor does this book simply focus on the development of a medical regime that subjected intersex infants to irreversible genital surgery. Rather, How the Clinic Made Gender explores the shifting landscapes of discussion about sex, gender, and sexuality in modern US history. The process by which ideas about gender became medicalized, enforced, and popularized was messy, and how gender came to be understood and applied through the treatment of patients with intersex traits was fraught and contested. This book is about the intricate ways in which the most intimate of ideas were put into practice in medicine and how those clinical practices, in turn, have informed our ideas about gender to this day"--
Gender and Health is the first book to examine how men's and women's lives and their physiology contribute to differences in their health. In a thoughtful synthesis of diverse literatures, the authors demonstrate that modern societies' health problems ultimately involve a combination of policies, personal behavior, and choice. The book is designed for researchers, policymakers, and others who seek to understand how the choices of individuals, families, communities, and governments contribute to health. It can inform men and women at each of these levels how to better integrate health implications into their everyday decisions and actions.
The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers! 2018 PROSE Awards - Winner, Award for Clinical Medicine: Association of American Publishers Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols