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This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery. - Brings together cutting-edge research on neuromodulation - Reviews current knowledge and understanding - Provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery
This edited volume presents fundamentals as well as applications of oculomotor methods in industrial and clinical settings. The topical spectrum covers 1.) basics and background material, 2.) methods such as recording techniques, markov models, Lévy flights, pupillometry and many more, as well as 3.) a broad range of applications in clinical and industrial settings. The target audience primarily comprises research experts and practitioners, but the book may also be beneficial for graduate students.
Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Parkinson's Disease and Beyond - A Neurocognitive Approach aims to bring together in a single publication the knowledge of diagnosis and characterization of the clinical and neuropsychological profile in Parkinson's disease. The strong impulse to research this topic has produced in recent years a large literature that documents the high level of complexity of the issue. Due to this complexity, a reasoned multidimensional analysis able to integrate expertise of different disciplines (neurology, neuropsychology, neuroradiology, and neuroscience) is necessary. This book offers an excellent synopsis of perspectives, methods, empirical evidences, and international references. It represents an extraordinary opportunity to target challenging unmet needs and to outline new horizons in Parkinson's disease research.
Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
International Review of Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the International Review of Neurobiology series
A neuroscientist and Zen practitioner interweaves the latest research on the brain with his personal narrative of Zen. Aldous Huxley called humankind's basic trend toward spiritual growth the "perennial philosophy." In the view of James Austin, the trend implies a "perennial psychophysiology"—because awakening, or enlightenment, occurs only when the human brain undergoes substantial changes. What are the peak experiences of enlightenment? How could these states profoundly enhance, and yet simplify, the workings of the brain? Zen and the Brain presents the latest evidence. In this book Zen Buddhism becomes the opening wedge for an extraordinarily wide-ranging exploration of consciousness. In order to understand which brain mechanisms produce Zen states, one needs some understanding of the anatomy, physiology, and chemistry of the brain. Austin, both a neurologist and a Zen practitioner, interweaves the most recent brain research with the personal narrative of his Zen experiences. The science is both inclusive and rigorous; the Zen sections are clear and evocative. Along the way, Austin examines such topics as similar states in other disciplines and religions, sleep and dreams, mental illness, consciousness-altering drugs, and the social consequences of the advanced stage of ongoing enlightenment.
Physiotherapy and rehabilitation applications in neurological diseases are important for the treatment of the disease. The basic principle of physiotherapy and rehabilitation is to determine the needs of the patient. As such, the authors discuss the evaluation of the motor functions of neurological diseases for upper and lower extremities separately, as well as sensorial functions and cognitive functions. Next, a literature review draws attention to studies in which sex was a controlled variable, and presents data regarding sexual dimorphism in a range of aspects developed after brain injury. It is possible to document the accomplishments of different cell death mechanisms and varying degrees of inflammatory response depending on the sex, as well as the distinct susceptibilities of the sexes in terms of mechanisms of cell damage. Additionally, summary of techniques and indications related to cerebrovascular bypass surgery for aneurysmal subarachnoid hemorrhage cases is provided, maintaining that cerebral revascularization procedures should be further developed by neurosurgeons as they remain the only option of treatment for a significant number of patients. The authors review their extensive experience with indocyanine green video-angiography and FLOW 800 analysis software during the surgical removal of central nervous system tumors; in particular, they identified 5 possible applications of indocyanine green video-angiography and FLOW 800 in this field. Data is presented showing the reciprocity between the brain angiotensin II system and amphetamine exposure in the development and expression of behavioral, neurochemical and glial alterations. Particularly, this collection explores how the neuroadaptative responses and neuroinflammation evoked by the psychostimulant and depending on AT1 receptors that might resemble some features linked to different brain disorders. Lastly, a brief overview of the investigational history in research work on receptor/G-protein coupling is presented. Subsequently, the most recent experimental results in the re-establishment of [35S]GTPyS binding/immunoprecipitation assay are described.
This third edition systematically reviews recent developments in the diagnosis and evidence-based treatment of cerebral palsy, a consequence of foetal and early infant brain damage resulting in lifelong disabilities with a range of clinical characteristics. The first part discusses the definition, aetiology, classification, imaging and neuropathology, while the second focuses on the management of the individual challenges that children with cerebral palsy face, such as spasticity, dyskinesia, feeding problems and scoliosis. Based on the diverse characteristics of cerebral palsy, children require care from various specialists, including neuro-paediatricians, orthopaedists, psychologists, epidemiologists, physiotherapists and occupational therapists. This work was written by an international team of such specialists, providing a comprehensive mix of perspectives and expertise.