Download Free High Dose Dosimetry Book in PDF and EPUB Free Download. You can read online High Dose Dosimetry and write the review.

Radiation Dosimetry focuses on the advancements, processes, technologies, techniques, and principles involved in radiation dosimetry, including counters and calibration and standardization techniques. The selection first offers information on radiation units and the theory of ionization dosimetry and interaction of radiation with matter. Topics include quantities derivable from roentgens, determination of dose in roentgens, ionization dosimetry of high-energy photons and corpuscular radiations, and heavy charged particles. The text then examines the biological and medical effects of radiation, as well as radiation effects in malignant tissues, levels of radiation, and mechanism of radiation effects on living cells. The publication takes a look at ionization chambers, Geiger-Mueller counters and proportional counters, scintillation detectors, and photographic film dosimetry, Discussions focus on calibration and standardization techniques, scintillating materials and their light yield, scintillation detector dosimetry of neutrons, and the physics of counters. The text also ponders on chemical and colorimetric indicators and survey instruments and pocket dosimeters. The selection is a dependable reference for readers interested in radiation dosimetry.
Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. - Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field - Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease - Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research
Optically Stimulated Luminescence (OSL) has become the technique of choice for many areas of radiation dosimetry. The technique is finding widespread application in a variety of radiation dosimetry fields, including personal monitoring, environmental monitoring, retrospective dosimetry (including geological dating and accident dosimetry), space dosimetry, and many more. In this book we have attempted to synthesize the major advances in the field, covering both fundamental understanding and the many applications. The latter serve to demonstrate the success and popularity of OSL as a dosimetry method.The book is designed for researchers and radiation dosimetry practitioners alike. It delves into the detailed theory of the process from the point of view of stimulated relaxation phenomena, describing the energy storage and release processes phenomenologically and developing detailed mathematical descriptions to enable a quantitative understanding of the observed phenomena. The various stimulation modes (continuous wave, pulsed, or linear modulation) are introduced and compared. The properties of the most important synthetic OSL materials beginning with the dominant carbon-doped Al2O3, and moving through discussions of other, less-well studied but nevertheless important, or potentially important, materials. The OSL properties of the two most important natural OSL dosimetry material types, namely quartz and feldspars are discussed in depth. The applications chapters deal with the use of OSL in personal, environmental, medical and UV dosimetry, geological dating and retrospective dosimetry (accident dosimetry and dating). Finally the developments in instrumentation that have occurred over the past decade or more are described. The book will find use in those laboratories within academia, national institutes and the private sector where research and applications in radiation dosimetry using luminescence are being conducted. Potential readers include personnel involved in radiation protection practice and research, hospitals, nuclear power stations, radiation clean-up and remediation, food irradiation and materials processing, security monitoring, geological and archaeological dating, luminescence studies of minerals, etc.
This revised and extended 6 volume handbook set is the most comprehensive and voluminous reference work of its kind in the field of nuclear chemistry. The Handbook set covers all of the chemical aspects of nuclear science starting from the physical basics and including such diverse areas as the chemistry of transactinides and exotic atoms as well as radioactive waste management and radiopharmaceutical chemistry relevant to nuclear medicine. The nuclear methods of the investigation of chemical structure also receive ample space and attention. The international team of authors consists of scores of world-renowned experts - nuclear chemists, radiopharmaceutical chemists and physicists - from Europe, USA, and Asia. The Handbook set is an invaluable reference for nuclear scientists, biologists, chemists, physicists, physicians practicing nuclear medicine, graduate students and teachers - virtually all who are involved in the chemical and radiopharmaceutical aspects of nuclear science. The Handbook set also provides further reading via the rich selection of references.
This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
This Code of Practice, which has also been endorsed by WHO, PAHO and ESTRO, fulfils the need for a systematic and internationally unified approach to the calibration of ionization chambers in terms of absorbed dose to water and to the use of these detectors in determining the absorbed dose to water for the radiation beams used in radiotherapy. It provides a methodology for the determination of absorbed dose to water in the low, medium and high energy photon beams, electron beams, proton beams and heavy ion beams used for external radiation therapy.
This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.
Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. With end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments, this book is a foundational resource that provides practical coverage of PBPK modeling for graduate students, academics, researchers, and more. - Provides end-of-chapter exercises to teach hands-on computational tools used in toxicology - Supplies computer code and explanations and includes examples of applied models used in regulatory toxicology and research - Authored by expert editors and contributors who are among the best PBPK modelers in the world
This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning. In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source. Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students.