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In collaboration with Consulting Editor, Dr. Norman Gitlin, Guest Editor Dr. Catherine Frenette has assembled expert authors to provide current updates on Hepatocellular Carcinoma (HCC). This issue asks important questions and provides answers and current thoughts on the staging and treatment of HCC. Clinical review articles are specifically dedicated to the following topics: The Changing Global Epidemiology of Hepatocellular Carcinoma; Prevention Strategies for HCC; Biomarkers or Biopsy for Diagnosis of HCC; Screening and Surveillance Strategies to Improve the Chance of Success; Imaging Diagnosis of HCC; Surgical Resection: Old dog--Any new tricks; Hepatocellular Carcinoma and Liver Transplant: How Will Organ Allocation Changes Affect the HCC Patient Within Transplant Criteria; Downstaging to Liver Transplant: Success Involves Choosing the Right Patient; Locoregional Therapies for Hepatocellular Carcinoma: What has Changed in the Past Ten Years; External Beam Radiotherapy: Is There a Place for This in HCC Treatment; Tyrosine Kinase Inhibitors and Hepatocellular Carcinoma; Immuno-oncology for Hepatocellular Carcinoma: The Present and the Future; Management of Side Effects of Systemic Therapies for HCC: Guide for the Hepatologist; and Why a Multi-disciplinary Tumor Board is Critical for Success with Hepatocellular Carcinoma. Readers will come away with the information they need to improve patient outcomes in the patient with HCC.
In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Pierre Gholam has put together topics that provide a current clinical update on the treatment and management of patients with drug-induced liver injury (DILI). Expert authors have contributed clinical review articles on the following topics: Epidemiology, Predisposing Factors and Outcomes; Genetic Predisposition to DILI; Causality Assessment Frequent Offenders and Patterns of Injury; Quantitative Systems Toxicology Approaches to Understand and Predict DILI; Liver Histology: Diagnostic and Prognostic Features; Acute Liver Failure Secondary to DILI; DILI in Persons with Pre-existing Chronic Liver Disease; DILI in the Setting of Statin Use; DILI in the Setting of Analgesic Use; DILI Secondary to Herbals and Dietary Supplements; and DILI Reporting and Resources for the Clinician. Readers will come away with the information they need to improve outcomes in patients with DILI.
With collaboration from Consulting Editor, Dr. Norman Gitlin Dr. Goldberg has assembled a state-of-the-art issue devoted to management of liver transplant patients. Expert authors have contributed current clinical reviews that covers the breadth of the pre- and post-surgical journey. Articles are specifically devoted to the following topics: Obesity management of liver transplant waitlist candidates and recipients; Expanding the limits of liver transplantation for hepatocellular carcinoma: Is there a limit; Frailty and sarcopenia in patients pre- and post-liver transplant; Achieving tolerance in liver transplantation: Where are we now and what does the future hold; Expanding role of donation after cardiac death donors; Optimizing selection of patients for simultaneous liver-kidney transplant; Keeping the patient with end-stage liver disease alive while awaiting transplant: Management of complications of portal hypertension; Expanding donor selection and recipient indications for living donor liver transplantation; The changing liver transplant recipient: From hepatitis C to NASH and alcohol; Cardiovascular risk stratification in liver transplant candidates; The role of machine perfusion in liver transplantation: Warm, Cold, or does it not matter; Paradigm shift in utilization of livers from hepatitis C-viremic donors into HCV-negative patients; Transplantation of elderly patients: Is there an upper age cutoff; Transplantation for acute alcoholic hepatitis: Controversies and early successes. Hepatologists will come away with the information they need to improve outcomes in liver transplant patients.
In this issue of Clinics in Liver Disease, Guest Editor Paul Kwo brings his considerable expertise to the topic of Alcoholic Hepatitis. Top experts in the field cover key topics such as the Epidemiology of Alcoholic Hepatitis, Nutrition in Those with Alcoholic Hepatitis, Current therapies for alcoholic hepatitis, Selection Criteria for Liver Transplantation for Acute Alcoholic Hepatitis, and more. - Provides in-depth, clinical reviews on Alcoholic Hepatitis, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 11 relevant, practice-oriented topics including Emerging Therapies for alcoholic hepatitis; Diagnosis of Alcoholic Hepatitis; Moderate Alcoholic Hepatitis; Current and Future Biomarkers in Alcoholic Hepatitis, and more.
In collaboration with Consulting Editor, Dr. Norman Gitlin, Guest Editors Drs. Andres Cardenas and Thomas Reiberger have created an up-to-date monograph on the complications of cirrhosis. They have secured top experts to contribute clinical review articles on the following topics: Non-invasive Detection of CSPH in cACLD; Prevention of First Decompensation in ACLD; Treatment of Acute Variceal Bleeding in 2020: When to Use TIPS; Prevention of Variceal Bleeding and Rebleeding by NSBB: A Tailored Approach; The Role of Hepatic Venous Pressure Gradient (HVPG); Measurement in the Management of Cirrhosis; Bacterial Infections in Cirrhosis as a Cause or Consequence of Decompensation; Nutrition in Chronic Liver Disease; Diagnosis and Management of Hepatic Encephalopathy; Discriminating Acute Decompensation from Acute-on-Chronic Liver; Management of Severe and Refractory Ascites; Monitoring Renal Function and Therapy of HRS patients with Cirrhosis; Coagulopathy in Cirrhosis; and Current Concepts of Cirrhotic Cardiomyopathy. Hepatologists will come away with the information they need to manage these patients.
In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Steven Flamm has put together another great update for the hepatology consult. Articles are submitted by expert author and in the format of the clinical review article, provide timely data for diagnosis and treatment. Specific areas addressed include the following: Management of esophageal and gastric varices; Severe thrombocytopenia in chronic liver disease and new management approaches; Pathology in chronic liver disease; Alpha 1 antitrypsin disease and chronic liver disease in adults; Evaluation of management of Budd-Chiari; HBV reactivation with immunosuppressive therapy; Homeopathic products and hepatotoxicity; New uses of TIPS; Dermatologic manifestations of chronic liver disease; Acute on chronic liver failure; Cholangiocarcinoma; Diagnosis and management of hepatic adenoma and focal nodular hyperplasia; Emerging data about the microbiome in chronic liver disease; and Acute viral hepatitis aside from HAV, HBV, and HCV. Readers will come away with the information they need to improve patient outcomes.
In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Sherouk Fouda and Joseph M. Pappachan bring their considerable expertise to the topic of Metabolic Associated Fatty Liver Disease. Top experts address the various ways metabolic associated fatty liver disease is related to other conditions such as diabetes, sarcopenia, PCOS, and more, as well as the management of MAFLD and cardiovascular implications. - Contains 12 practice-oriented topics including obstructive sleep apnea and MAFLD; the interlink between MAFLD and polycystic ovary syndrome; pregnancy and MAFLD; MAFLD and gut microbiota; and more. - Provides in-depth clinical reviews of metabolic associated fatty liver disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
In this issue of Surgical Clinics, guest editor Dr. Shimul Shah brings his considerable expertise to the topic of Liver Transplantation and Transplantation Oncology. Top experts in the field review the current status of liver transplantation in North America, outcomes involving living versus deceased donors, transplants for different liver diseases, machine perfusion, and immunotherapy. - Contains 16 relevant, practice-oriented topics including outcomes of living donor liver transplantation compared to deceased donor liver transplantation; living donor liver transplantation: left lobe or right lobe; current status of liver transplantation in North America; current use of immunosuppression in liver transplantation; expanding the boundaries for liver transplantation for hepatocellular carcinoma; and more. - Provides in-depth clinical reviews on liver transplantation and transplantation oncology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Adoption of video capsule endoscopy has been slow, but there are now four FDA-approved devices and others available in China. It is now generally realized that there is an expanding role for these devices, not only in the small intestine but in the GI tract in general. In collaboration with Consulting Editor, Dr. Charles Lightdale, guest editor Dr. David Cave has assembled expert authors to provide clinical reviews that address where we are now, areas of controversy that still need resolution, and where the field is likely to develop over the next 5 to 10 years. Articles are specifically devoted to the following topics: Training, Reading and Reporting for Video Capsule Endoscopy; Indications and Contraindications: Complications of Capsule Endoscopy; Preparation, Prokinetics, and Surface Active Agents; Role of Capsule in Small Intestinal Bleeding; Role of Capsule Endoscopy in IBD; Role of Video Capsule Endoscopy in Liver Disease; Role of Video Capsule Endoscopy in Alternative Settings; Timing and Use of the Capsule Endoscopy in the Acute Care Setting; Role of Video Capsule Endoscopy as a Prelude to Deep Enteroscopy; Location of Capsule and Provocation Testing; Cost Effectiveness of Video Capsule Endoscopy; Artificial Intelligence in Capsule Endoscopy; and Novel Clinical Applications and Technical Developments in Video Capsule Endoscopy.