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This is a thoroughly revised, updated and rewritten edition of the book reflecting guidelines and studies till early 2020. It contains original Jopling’s clinical text which has been updated with over 370 images and diagrams. It will serve as a textbook for postgraduate students in dermatology as well as a ready-reckoner for all health personnel dealing with leprosy at various levels.
For health workers
Leprosy (Hansen’s disease) is an infectious disease caused by Mycobacterium leprae. It is one of the most disabling disorders in developing countries, with a peak incidence in the tropics and subtropics. With globalization, leprosy is now increasingly spreading to the western world. The impact of this infectious disorder is relevant for the human community due to its transmissible nature, and also important for the individual because of its debilitating consequences. Leprosy is a multifaceted systemic disease with variable presentation and clinical picture. Its identification may therefore not be straightforward, especially outside endemic areas. During its chronic course, leprosy is characterized by acute phases during which there may be exacerbation of symptoms and rapid progression of damage. When leprosy affects the eyes, nerves, and kidneys, it can represent a true medical emergency. The aim of this book is to make the reader familiar with the characteristic signs of disease, including abnormalities of the skin, nerves, eyes, hands, feet, testes, and bone. Early identification of the disease is critical to prevent patient disability and establish appropriate therapy. Emphasis will be given to the current diagnostic tools to identify and quantify the organ damage, including electrophysiology, ultrasonography, magnetic resonance imaging, laboratory tests, and histopathology. Specific topics such as leprosy and pregnancy, leprosy and HIV infection, epidemiology, and leprosy control will also be covered.
Histopathological Diagnosis of Leprosy, is a comprehensive guide to the medical pathology of Hansen’s disease, which is a complex and clinically challenging infection caused by Mycobacterium leprae. Readers will find 8 chapters on key topics on the subject including general aspects of leprosy, different forms of leprosy (polar, borderline, etc.), reaction types and complications. The information presented in the handbook will equip the reader with the knowledge required to identify the disease in patients and perform differential diagnosis where required. Key Features: - 8 chapters dedicated to key topics about leprosy and its diagnosis - More than 2014 figures featuring over 1000 clinical and histopathological photographs - Complete information about differential diagnosis and reaction phenomena - includes a section dedicated to special and complicated cases - References for further reading - Brings the expertise of renowned physicians to the reader The detailed presentation of the book is of great value to both healthcare professionals (pathologists, dermatologists, physicians) who are involved in the care of leprosy patients, and medical residents who are seeking information about the disease as part of their medical training.
The Biology of Leprosy Bacteria and How They Are Transmitted to Humans -- How Leprosy Affects the Human Body -- Past and Present Diagnosis, Treatment, and Prognosis -- The Bioarchaeology of Leprosy -- The Bioarchaeological Evidence of Leprosy -- Reconstructing the Origin, Evolution, and History of Leprosy -- Conclusions: A Future for Leprosy; Clinical and Bioarchaeological Perspectives.
Lying in a hospital bed, José P. Ramirez, Jr. (b. 1948) almost lost everything because of a misunderstood disease. When the health department doctor gave him the Handbook for Persons with Leprosy, Ramirez learned his fate. Such a diagnosis in 1968 meant exile and hospitalization in the only leprosarium in the continental United States—Carville, Louisiana, 750 miles from his home in Laredo, Texas. In Squint: My Journey with Leprosy, Ramirez recalls being taken from his family in a hearse and thrown into a world filled with fear. He and his loved ones struggled against the stigma associated with the term “leper” and against beliefs that the disease was a punishment from God, that his illness was highly communicable, and that persons with Hansen's disease had to be banished from their communities. His disease not only meant separation from the girlfriend who would later become his wife, but also a derailment of all life's goals. In his struggle Ramirez overcame barriers both real and imagined and eventually became an international advocate on behalf of persons with disabilities. In Squint, titled for the sliver of a window through which persons with leprosy in medieval times were allowed to view Mass but not participate, Ramirez tells a story of love and perseverance over incredible odds.
The essential guide to controlling and managing today’s communicable diseases The fourth edition of Communicable Disease Control and Health Protection Handbook offers public health workers of all kinds an authoritative and up-to-date guide to current protocols surrounding the identification and control of infectious diseases. With its concise, accessible design, the book is a practical tool that can be relied upon to explain topics ranging from the basic principles of communicable disease control to recent changes and innovations in health protection practice. Major syndromes and individual infections are insightfully addressed, while the authors also outline the WHO’s international health regulations and the organizational arrangements in place in all EU nations. New to the fourth edition are chapters on Ebola, the Zika virus, and other emerging pandemics. In addition, new writing on healthcare-associated infection, migrant and refugee health, and the importance of preparedness make this an essential and relevant text for all those in the field. This vital resource: Reflects recent developments in the science and administration of health protection practice Covers topics such as major syndromes, control of individual infections, main services and activities, arrangements for all European countries, and much more Includes new chapters on the Zika virus, Schistosomiasis, Coronavirus including MERS + SARS, and Ebola Follows a format designed for ease of use and everyday consultation Created to provide public and environmental health practitioners, physicians, epidemiologists, infection control nurses, microbiologists and trainees with a straightforward – yet informative – resource, Communicable Disease Control and Health Protection Handbook is a practical companion for all those working the field today.
This popular book is written by the award-winning teacher, Dr. Leon Gordis of the Bloomberg School of Public Health at Johns Hopkins University. He introduces the basic principles and concepts of epidemiology in clear, concise writing and his inimitable style. This book provides an understanding of the key concepts in the following 3 fully updated sections: Section I: The Epidemiologic Approach to Disease and Intervention; Section II: Using Epidemiology to Identify the Causes of Disease; Section III: Applying Epidemiology to Evaluation and Policy. Clear, practical graphs and charts, cartoons, and review questions with answers reinforce the text and aid in comprehension. Utilizes new full-color format to enhance readability and clarity. Provides new and updated figures, references and concept examples to keep you absolutely current - new information has been added on Registration of Clinical Trials, Case-Cohort Design, Case-Crossover Design, and Sources and Impact of Uncertainty (disease topics include: Obesity, Asthma, Thyroid Cancer, Helicobacter Pylori and gastric/duodenal ulcer and gastric cancer, Mammography for women in their forties) - expanded topics include Person-time. Please note: electronic rights were not granted for several images in this product. Introduces both the underlying concepts as well as the practical uses of epidemiology in public health and in clinical practice. Systemizes learning and review with study questions in each section and an answer key and index. Illustrates textual information with clear and informative full-color illustrations, many created by the author and tested in the classroom.
Leprosy has afflicted humans for thousands of years. It wasn't until the twelfth century, however, that the dreaded disease entered the collective psyche of Western society, thanks to a frightening epidemic that ravaged Catholic Europe. The Church responded by constructing charitable institutions called leprosariums to treat the rapidly expanding number of victims. As important as these events were, Timothy Miller and John Nesbitt remind us that the history of leprosy in the West is incomplete without also considering the Byzantine Empire, which confronted leprosy and its effects well before the Latin West. In Walking Corpses, they offer the first account of medieval leprosy that integrates the history of East and West.In their informative and engaging account, Miller and Nesbitt challenge a number of misperceptions and myths about medieval attitudes toward leprosy (known today as Hansen’s disease). They argue that ethical writings from the Byzantine world and from Catholic Europe never branded leprosy as punishment for sin; rather, theologians and moralists saw the disease as a mark of God’s favor on those chosen for heaven. The stimulus to ban lepers from society and ultimately to persecute them came not from Christian influence but from Germanic customary law. Leprosariums were not prisons to punish lepers but were centers of care to offer them support; some even provided both male and female residents the opportunity to govern their own communities under a form of written constitution. Informed by recent bioarchaeological research that has vastly expanded knowledge of the disease and its treatment by medieval society, Walking Corpses also includes three key Greek texts regarding leprosy (one of which has never been translated into English before).