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Leading international experts summarize up-to-date findings on the presentation, diagnosis, pathogenesis and therapy of cerebral artery dissection. Several topics, such as the first animal model of cervical artery dissection, the epidemiology and its association with connective tissue abnormalities in skin and arteries, genetic approaches in the study of risk factors as well as the main etiologies of spontaneous and traumatic cervical artery dissection are discussed. The book also gives an insight into the clinical manifestations of carotid and vertebral artery dissection and to the possibilities and limitations of the main diagnostic tools, ultrasound, CT and MR imaging, and angiography. The last part of the publication presents the prognosis, thrombolysis and antithrombotic therapy of cervical artery dissection and concludes with an overview of intracranical dissection. Specialists in neurology, neuroradiology, neurosurgery, internal medicine as well as general practitioners will find this publication a useful and unique review of the present knowledge and future research directions of this still poorly understood disease.
Carotid and vertebral artery dissections are responsible for one-quarter of strokes in young adults. Despite this fact, there is very little awareness and understanding of these vascular injuries by the public, and even by healthcare providers. This book answers the common questions that patients with carotid and vertebral artery dissections have with easy-to-understand explanations. Also included are stories from patients who have persevered after their dissections. Their tales personalize dissection and stroke in young adults in an undeniable way, and illustrate the existence of the lingering effects dissections can have on patients for years. Jodi A. Dodds, MD, a vascular neurologist at Duke University, and Amanda P. Anderson, MS, CCC-SLP, a speech-language pathologist and a survivor of a severe carotid artery dissection, have created an important and needed resource for patients and their families as they navigate through the aftermath of this life-changing event.
Neurosonology is non-invasive, portable, and has excellent temporal resolution, making it a valuable and increasingly popular tool for the diagnosis and monitoring of neurological conditions when compared to other imaging techniques. This guide looks beyond the use of neurovascular ultrasound in stroke to encompass a wide range of other neurological diseases and emergencies. It offers a practical approach to the examination of patients, interpretation of ultrasound studies, and the application of neurosonology to the development of management and treatment strategies. Each chapter incorporates a thorough and clear procedural methodology alongside scanning tips for trainees; this step-by-step approach is further enhanced by example images and focused diagnostic questions. Authored and edited by international experts, this practical manual of neurosonology is an invaluable resource for neurologists, neurosurgeons, intensivists, radiologists, and ultrasonographers.
The Human Brain in Dissection will significantly update the previous edition published in 1988. The last 20 years have sen a significant shift in the way that neuroanatomy is taught in both undergraduate and graduate neuroscience courses, as well as doctorate courses: not only has the time allocated for these courses been reduced, but the methodologies for teaching have become more focused and specific due to these time constraints. The Human Brain in Dissection, Third Edition will provide detailed features of the human brain with the above limitations in mind. 50 new plates will be added to the existing 123 in order to permit the student to see all salient structures and to visualize microscopic structures of the brain stem and spinal cord. Each chapter will cover a specific are of the human brain in such a way that each chapter can be taught in one two-hour neuroanatomy course. New to this edition is the inclusion of a section in each chapter on clinically relevant examples. Each chapter will also include a specific laboratory exercise. And finally, the author has included a question and answer section that is relevant to the USMLE, as as recommended readings, neither of which were included in the previous editions. This new edition of The Human Brain in Dissection will allow the student to: understand basic principles of cellular neuroscience; learn gross and microscopic anatomy of the central nervous system (Brain, brainstem, and spinal cord); relate the anatomy of central neural pathways to specific functional systems; be able to localize and name a CNS legion when presented with neurological symptoms, and appreciate higher cortical functions and how they relate to the practice of neurology. neuroscience
Fully revised and updated, the Handbook serves as a practical guide to endovascular methods and as a concise reference for neurovascular anatomy and published data about cerebrovascular disease from a neurointerventionalist’s perspective. Divided into three parts, the book covers: Fundamentals of neurovascular anatomy and basic angiographic techniques; Interventional Techniques and endovascular methods, along with useful device information and tips and tricks for daily practice; Specific Disease States, with essential clinical information about commonly encountered conditions. New features in the 2nd Edition include: Global Gems that illuminate aspects of the field outside the United States; Angio-anatomic and angio-pathologic image correlates; Newly released clinical study results influencing neurointerventional practice; Information on emerging technologies in this rapidly advancing field. The Handbook is a vital resource for all clinicians involved in neurointerventional practice, including radiologists, neurosurgeons, neurologists, cardiologists, and vascular surgeons.
Neurovascular ultrasound increases the reliability of assessing occlusive cerebrovascular disease, including the detection of instable carotid plaques, the delineation of cerebral perfusion and therapeutic options such as ultrasound-enhanced sonothrombolysis. Written by international experts, this publication provides the reader with the present knowledge and future research directions of diagnostic and therapeutic neurovascular ultrasound. The first chapters deal with physical and technical principles of ultrasound, arterial wall imaging, endothelial function testing and modern assessment of atherosclerotic obstruction of the carotid and vertebro-basilar systems. Subsequently, typical ultrasound findings in cervical artery dissection, dural fistula, glomus tumor and vasculitis are reported. The book concludes with the description of diagnostic and therapeutic transcranial ultrasound and clinical applications of transcranial Doppler monitoring as well as the presentation of future developments. Neurologists, angiologists and radiologists will find a valuable source of up-to-date information on this fascinating, essentially non-invasive technique, which allows real-time assessment of the human cerebral vessels.
Cerebral Angiography is a comprehensive and well-illustrated guide to the diagnostic use of cerebral angiography. The first part of the book depicts in detail the normal appearance of the cerebral vessels on angiographic studies. Sound knowledge of this normal vascular anatomy and clinical function is vital for correct interpretation of the clinical significance of the pathological processes addressed in the second part of the book. The latter include vascular abnormalities, including angiomas, fistulas, and aneurysms; atherosclerotic and non-atherosclerotic stenosis and occlusion of the cerebral vessels; and venous thrombosis. In each case, both typical and atypical appearances are presented. While the emphasis throughout is on the diagnostic value of cerebral angiography, a number of examples of endovascular treatment are also included to highlight the evolving possibilities of therapy and the role of cerebral angiography in treatment selection.
Neurointerventional radiology is evolving into a rarified and complex field, with more people today training to become neurointerventionalists than ever before. With these developments comes a need for a unified handbook of techniques and essential literature. In Handbook of Cerebrovascular Disease and Neurointerventional Technique, Mark Harrigan and John Deveikis present the first practical guide to endovascular methods and provide a viable reference work for neurovascular anatomy and cerebrovascular disease from a neurointerventionalist’s perspective. This new gold-standard reference covers the fundamental techniques and core philosophies of Neurointerventional radiology, while creating a manual that offers structure and standardization to the field. Authoritative and concise, Handbook of Cerebrovascular Disease and Neurointerventional Technique is the must-have work for today’s neurosurgeons, neuroradiologists, and interventional radiologists.
Intracranial atherosclerosis is a leading cause of stroke in Asians and Africans. As these ethnic groups account for more than 70% of the world’s population, it is in fact the major cause of ischemic stroke worldwide. This timely book provides readers with up-to-date knowledge of intracranial atherosclerosis, covering vascular anatomy, pathology, epidemiology, stroke mechanisms and syndromes, diagnostic methods as well as treatment strategies such as antithrombotics, angioplasty/stenting and surgery. Furthermore, nonatherosclerotic intracranial arterial diseases like Moyamoya disease, dissection, vasculitis and other miscellaneous disorders are extensively discussed. Experts from both East and West present the latest findings from cutting-edge research and discuss controversial topics from different yet balanced points of view, allowing readers to form their own unbiased opinion on these issues. With this approach, the book serves as a useful and stimulating guide on the diagnosis and management of intracranial atherosclerosis for neurologists, neurosurgeons, neuroradiologists and vascular interventionists.
Isolated dissection of the posterior cerebral artery (pCA) is a rare but important cause of stroke in younger patients, particularly women. We present three cases of dissection of the P2 segment of the PCA. In two patients, an association with minor axial head trauma was documented, suggesting shearing injury of the PCA as it crosses over the free edge of the tentorium. The clinical and imaging findings are discussed, and the therapeutic management is reviewed. Extracranial and intracranial arterial dissection is an important cause of stroke in younger patients. Intracranial arterial dissections most often involve the vertebrobasilar system and, less commonly, the middle and anterior cerebral arteries. Isolated dissection of the PCA is rare, but accurate diagnosis is important for appropriate clinical management. We present three cases of dissection of the P2 segment of the PCA, two of which occurred in association with minor head trauma.